scholarly journals Using Genetic Proxies for Lifecourse Sun Exposure to Assess the Causal Relationship of Sun Exposure with Circulating Vitamin D and Prostate Cancer Risk

2013 ◽  
Vol 22 (4) ◽  
pp. 597-606 ◽  
Author(s):  
Carolina Bonilla ◽  
Rebecca Gilbert ◽  
John P. Kemp ◽  
Nicholas J. Timpson ◽  
David M. Evans ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Vitamin D ◽  
Cancer Risk ◽  
Causal Relationship ◽  
Prostate Cancer Risk ◽  
Sun Exposure ◽  
Relationship Of

scholarly journals Vitamin D, Sunlight and Prostate Cancer Risk

2011 ◽  
Vol 2011 ◽  
pp. 1-13 ◽  
Author(s):  
Krishna Vanaja Donkena ◽  
Charles Y. F. Young
Keyword(s):  
Prostate Cancer ◽  
Vitamin D ◽  
Cancer Risk ◽  
Prostate Cancer Risk ◽  
Vitamin D Metabolites ◽  
Metabolizing Enzymes ◽  
Prostate Cancer Prevention ◽  
Epidemiology Studies ◽  
Relationship Of ◽  
The Relationship

Prostate cancer is the second common cancer in men worldwide. The prevention of prostate cancer remains a challenge to researchers and clinicians. Here, we review the relationship of vitamin D and sunlight to prostate cancer risk. Ultraviolet radiation of the sunlight is the main stimulator for vitamin D production in humans. Vitamin D's antiprostate cancer activities may be involved in the actions through the pathways mediated by vitamin D metabolites, vitamin D metabolizing enzymes, vitamin D receptor (VDR), and VDR-regulated genes. Although laboratory studies including the use of animal models have shown that vitamin D has antiprostate cancer properties, whether it can effectively prevent the development and/or progression of prostate cancer in humans remains to be inconclusive and an intensively studied subject. This review will provide up-to-date information regarding the recent outcomes of laboratory and epidemiology studies on the effects of vitamin D on prostate cancer prevention.

scholarly journals Vitamin D and prostate cancer risk: a review of the epidemiological literature

2009 ◽  
Vol 12 (3) ◽  
pp. 215-226 ◽  
Author(s):  
D Gupta ◽  
C A Lammersfeld ◽  
K Trukova ◽  
C G Lis
Keyword(s):  
Prostate Cancer ◽  
Vitamin D ◽  
Cancer Risk ◽  
Prostate Cancer Risk

Abstract B18: Interactions between finasteride and vitamin D-related polymorphisms is associated with prostate cancer risk in African American men

2015 ◽  
Author(s):  
Kathleen C. Torkko ◽  
Cathee Till ◽  
Phyllis J. Goodman ◽  
Catherine M. Tangen ◽  
Adrie van Bokhoven ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Vitamin D ◽  
African American ◽  
Cancer Risk ◽  
African American Men ◽  
Prostate Cancer Risk

scholarly journals Association between dietary inflammatory index and prostate cancer among Italian men

2014 ◽  
Vol 113 (2) ◽  
pp. 278-283 ◽  
Author(s):  
Nitin Shivappa ◽  
Cristina Bosetti ◽  
Antonella Zucchetto ◽  
Maurizio Montella ◽  
Diego Serraino ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Smoking Status ◽  
Wide Spectrum ◽  
Prostate Cancer Risk ◽  
Dietary Inflammatory Index ◽  
Logistic Regression Models ◽  
Inflammatory Index ◽  
History Of ◽  
Relationship Of

Previous studies have shown that various dietary components may be implicated in the aetiology of prostate cancer, although the results remain equivocal. The possible relationship of inflammation derived from dietary exposures with prostate cancer risk has not been investigated. We examined the ability of a newly developed dietary inflammatory index (DII) to predict prostate cancer risk in a case–control study conducted in Italy between 1991 and 2002. A total of 1294 patients aged < 75 years with incident, histologically confirmed carcinoma of the prostate served as cases. A total of 1451 subjects aged < 75 years who were admitted to the same hospitals as cases for a wide spectrum of acute, non-neoplastic conditions served as controls. The DII was computed based on dietary intake assessed using a previously validated seventy-eight-item FFQ. Logistic regression models were used to estimate multivariable OR adjusted for age, study centre, years of education, social class, BMI, smoking status, family history of prostate cancer and total energy intake. Men with higher DII scores had a higher risk of prostate cancer when analysed using the DII as both continuous (OR 1·06, 95 % CI 1·00, 1·13) and categorical, i.e. compared with men in the lowest quartile of the DII, men in the third and fourth quartiles were at elevated risk (ORQuartile 3 v. 1 1·32, 95 % CI 1·03, 1·69 and ORQuartile 4 v. 1 1·33, 95 % CI 1·01, 1·76; Ptrend= 0·04). These data suggest that a pro-inflammatory diet, as indicated by the increasing DII score, is a risk factor of prostate cancer in Italian men.

scholarly journals MP04-04 RELATIONSHIP OF TESTOSTERONE TREATMENT AND INCIDENT PROSTATE CANCER RISK AMONG U.S. VETERANS WITH LOW SERUM TESTOSTERONE

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Thomas Walsh ◽  
Molly Shores ◽  
Nicholas Smith ◽  
Mary Lou Thompson ◽  
Alexandra Fox ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Prostate Cancer Risk ◽  
Serum Testosterone ◽  
Testosterone Treatment ◽  
Relationship Of ◽  
Low Serum

VITAMIN D RECEPTOR POLYMORPHISMS AND PROSTATE CANCER RISK IN AN EUROPEAN POPULATION

1999 ◽  
pp. 56
Author(s):  
Thomas Paiss ◽  
Jurgen E. Gschwend ◽  
Michael Autenrieth ◽  
Lina Correa-Cerro ◽  
Jurgen Haussler ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Vitamin D ◽  
Cancer Risk ◽  
Vitamin D Receptor ◽  
Prostate Cancer Risk ◽  
European Population
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