Abstract PR14: Phase I trial of first-in-class ataxia telangiectasia-mutated and Rad3-related (ATR) inhibitor VX-970 as monotherapy (mono) or in combination with carboplatin (CP) in advanced cancer patients (pts) with preliminary evidence of target modulation and antitumor activity

2015 ◽  
Author(s):  
Timothy A. Yap ◽  
Maria J. de Miguel Luken ◽  
Brent O'Carrigan ◽  
Desam Roda ◽  
Dionysis Papadatos-Pastos ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Phase I ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Ataxia Telangiectasia ◽  
Phase I Trial ◽  
Preliminary Evidence ◽  
Ataxia Telangiectasia Mutated ◽  
Advanced Cancer Patients

Final results of a first-in-human phase I trial of PBI-05204, an inhibitor of AKT, FGF-2, NF-Kb, and p70S6K in advanced cancer patients.

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 3023-3023 ◽  
Author(s):  
H. A. Henary ◽  
R. Kurzrock ◽  
G. S. Falchook ◽  
A. Naing ◽  
S. L. Moulder ◽  
...  
Keyword(s):  
Phase I ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Phase I Trial ◽  
Advanced Cancer Patients

A phase I trial with recombinant interferon γ (Roussel UCLAF) in advanced cancer patients

1990 ◽  
Vol 32 (1) ◽  
pp. 67-70 ◽  
Author(s):  
François Boue ◽  
Zulay Pastran ◽  
Marc Spielmann ◽  
Thierry Le Chevalier ◽  
Rosana Subirana ◽  
...  
Keyword(s):  
Phase I ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Phase I Trial ◽  
Interferon Γ ◽  
Advanced Cancer Patients ◽  
Recombinant Interferon

Phase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients

2015 ◽  
Vol 64 (9) ◽  
pp. 1159-1173 ◽  
Author(s):  
Maria Grazia Cusi ◽  
Cirino Botta ◽  
Pierpaolo Pastina ◽  
Maria Grazia Rossetti ◽  
Elena Dreassi ◽  
...  
Keyword(s):  
Phase I ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Thymidylate Synthase ◽  
Phase I Trial ◽  
Advanced Cancer Patients ◽  
Epitope Peptide
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