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Abstract 1690: Definition of dose-limiting toxicity in phase I cancer clinical trials of molecularly targeted agents
Mapping Intimacies
◽
10.1158/1538-7445.am2011-1690
◽
2011
◽
Author(s):
Christophe Le Tourneau
◽
Albiruni R.A. Razak
◽
Hui K. Gan
◽
Simona Pop
◽
Xavier Paoletti
Keyword(s):
Clinical Trials
◽
Phase I
◽
Cancer Clinical Trials
◽
Targeted Agents
◽
Molecularly Targeted Agents
◽
Definition Of
◽
Dose Limiting Toxicity
Download Full-text
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References
Heterogeneity in the definition of dose-limiting toxicity in phase I cancer clinical trials of molecularly targeted agents: A review of the literature
European Journal of Cancer
◽
10.1016/j.ejca.2011.03.016
◽
2011
◽
Vol 47
(10)
◽
pp. 1468-1475
◽
Cited By ~ 39
Author(s):
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Keyword(s):
Clinical Trials
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Cancer Clinical Trials
◽
Targeted Agents
◽
Review Of The Literature
◽
Molecularly Targeted Agents
◽
Definition Of
◽
Dose Limiting Toxicity
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1260 POSTER Preliminary Signs of Efficacy Reported in Monotherapy Phase I Cancer Clinical Trials of Molecularly Targeted Agents and Correlation With Further Clinical Development
European Journal of Cancer
◽
10.1016/s0959-8049(11)70872-3
◽
2011
◽
Vol 47
◽
pp. S162-S163
Author(s):
J. Arrondeau
◽
X. Paoletti
◽
S. Pop
◽
P. Tresca
◽
V. Dieras
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...
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Clinical Trials
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Phase I
◽
Clinical Development
◽
Cancer Clinical Trials
◽
Targeted Agents
◽
Molecularly Targeted Agents
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Choice of starting dose for molecular targeted agents (MTA) evaluated in phase I cancer clinical trials (P1T)
Journal of Clinical Oncology
◽
10.1200/jco.2008.26.15_suppl.3586
◽
2008
◽
Vol 26
(15_suppl)
◽
pp. 3586-3586
Author(s):
L. Vidal-Boixader
◽
C. Le Tourneau
◽
L. L. Siu
Keyword(s):
Clinical Trials
◽
Phase I
◽
Cancer Clinical Trials
◽
Targeted Agents
◽
Starting Dose
◽
Molecular Targeted Agents
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Outcomes of Patients with Metastatic Melanoma Treated with Molecularly Targeted Agents in Phase I Clinical Trials
Oncology
◽
10.1159/000330206
◽
2011
◽
Vol 81
(2)
◽
pp. 135-140
◽
Cited By ~ 3
Author(s):
Montserrat Blanco Codesido
◽
Andre Tesainer Brunetto
◽
Sophia Frentzas
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Victor Moreno Garcia
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Dionysis Papadatos-Pastos
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Keyword(s):
Clinical Trials
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Phase I
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Metastatic Melanoma
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A Bayesian phase I/II design for cancer clinical trials combining an immunotherapeutic agent with a chemotherapeutic agent
Journal of the Royal Statistical Society Series C (Applied Statistics)
◽
10.1111/rssc.12508
◽
2021
◽
Author(s):
Beibei Guo
◽
Elizabeth Garrett‐Mayer
◽
Suyu Liu
Keyword(s):
Clinical Trials
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Phase I
◽
Chemotherapeutic Agent
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Cancer Clinical Trials
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Immunotherapeutic Agent
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Efficiency of New Dose Escalation Designs in Dose-Finding Phase I Trials of Molecularly Targeted Agents
PLoS ONE
◽
10.1371/journal.pone.0051039
◽
2012
◽
Vol 7
(12)
◽
pp. e51039
◽
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Author(s):
Christophe Le Tourneau
◽
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◽
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◽
Dose Escalation
◽
Dose Finding
◽
Phase I Trials
◽
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◽
Molecularly Targeted Agents
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384 POSTER Effect of selection of QTc formula on eligibility of patients for phase I cancer clinical trials
European Journal of Cancer Supplements
◽
10.1016/s1359-6349(08)72318-8
◽
2008
◽
Vol 6
(12)
◽
pp. 120
Author(s):
M. Benjamin
◽
D. Casa
◽
W. Tembe
◽
B. Piper
◽
S. Anthony
◽
...
Keyword(s):
Clinical Trials
◽
Phase I
◽
Cancer Clinical Trials
◽
Selection Of
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Precision Medicine for Molecularly Targeted Agents and Immunotherapies in Early-Phase Clinical Trials
Translational Oncogenomics
◽
10.4137/tog.s30533
◽
2015
◽
Vol Suppl. 1
◽
pp. 1-11
◽
Cited By ~ 3
Keyword(s):
Clinical Trials
◽
Precision Medicine
◽
Early Phase
◽
Targeted Agents
◽
Molecularly Targeted Agents
◽
Early Phase Clinical Trials
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A Bayesian seamless phase I–II trial design with two stages for cancer clinical trials with drug combinations
Biometrical Journal
◽
10.1002/bimj.201900095
◽
2020
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Vol 62
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◽
pp. 1300-1314
◽
Cited By ~ 1
Author(s):
José L. Jiménez
◽
Sungjin Kim
◽
Mourad Tighiouart
Keyword(s):
Clinical Trials
◽
Phase I
◽
Trial Design
◽
Drug Combinations
◽
Cancer Clinical Trials
◽
Two Stages
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Phase I Cancer Clinical Trials
Encyclopedia of Biopharmaceutical Statistics
◽
10.3109/9781439822463.161
◽
2010
◽
pp. 1011-1015
Author(s):
Seung‐Ho Kang
◽
Chul Ahn
Keyword(s):
Clinical Trials
◽
Phase I
◽
Cancer Clinical Trials
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