Abstract 3578: A novel and selective 3-phosphoinositide-dependent kinase-1 inhibitor, PF-5177624, blocks insulin-like growth factor-1 induced tumorigenesis in breast cancer cells

2011 ◽  
Author(s):  
Sangita M. Baxi ◽  
Marlena Walls ◽  
Sean Murphy ◽  
Jacques Ermolieff ◽  
Tod Smeal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Growth Factor ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Insulin Like Growth Factor ◽  
Phosphoinositide Dependent Kinase

scholarly journals Insulin-like growth factor II modulates the routing of cathepsin D in MCF-7 breast cancer cells.

Endocrinology ◽  
1996 ◽  
Vol 137 (5) ◽  
pp. 1851-1859 ◽  
Author(s):  
D D De Leon ◽  
C Terry ◽  
Y Asmerom ◽  
P Nissley
Keyword(s):  
Breast Cancer ◽  
Growth Factor ◽  
Cancer Cells ◽  
Cathepsin D ◽  
Breast Cancer Cells ◽  
Insulin Like Growth Factor ◽  
Factor Ii ◽  
Mcf 7
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