Abstract 382: Identification and characterization of circulating tumor cells with multiplexed Quantum Dot conjugated antibodies

2015 ◽  
Author(s):  
Lanlan Zhou ◽  
Elizabeth M. Matthew ◽  
David T. Dicker ◽  
Wafik S. El-Deiry
Keyword(s):  
Quantum Dot ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Identification And Characterization

Design of a Microfluidic Chip for Enrichment of Circulating Tumor Cells

2015 ◽  
Vol 645-646 ◽  
pp. 1320-1325
Author(s):  
Xi Xin Ling ◽  
Da Hai Ren ◽  
Zheng You
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Microfluidic Chip ◽  
Comsol Multiphysics ◽  
Enrichment Method ◽  
Cancer Metastases ◽  
Simulation Results ◽  
Novel Design ◽  
Identification And Characterization

Identification and characterization of CTCs can be used as a tool for the study of cancer metastases. A novel design of microfluidic chip used for enrichment of circulating tumor cells is presented in this paper. An integration of DLD method and negative enrichment method were designed to improve the throughput and recovery rate while getting intact CTCs. The DLD stage is used to separate CTCs from blood cells preliminarily, and the negative enrichment stage is used to acquire purified CTCs. Both of them were simulated with COMSOL Multiphysics. Simulation results showed that triangular micro-posts have better performance in DLD stage, and wave structures could generate better disturbance effect than herringbone structures. This chip provides a potential approach with high throughput and purity for the enrichment of CTCs.

Identification and Characterization of Circulating Tumor Cells in Men Who have Undergone Prostatectomy for Clinically Localized, High Risk Prostate Cancer

2019 ◽  
Vol 202 (4) ◽  
pp. 732-741 ◽  
Author(s):  
Terence W. Friedlander ◽  
Christopher Welty ◽  
Archana Anantharaman ◽  
Joseph D. Schonhoft ◽  
Adam Jendrisak ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
High Risk ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
High Risk Prostate Cancer ◽  
Risk Prostate Cancer ◽  
Identification And Characterization

scholarly journals Technical Insights into Highly Sensitive Isolation and Molecular Characterization of Fixed and Live Circulating Tumor Cells for Early Detection of Tumor Invasion

PLoS ONE ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. e0169427 ◽  
Author(s):  
Sophie Laget ◽  
Lucile Broncy ◽  
Katia Hormigos ◽  
Dalia M. Dhingra ◽  
Fatima BenMohamed ◽  
...  
Keyword(s):  
Early Detection ◽  
Tumor Cells ◽  
Molecular Characterization ◽  
Circulating Tumor Cells ◽  
Tumor Invasion ◽  
Highly Sensitive
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