Abstract 4598: Low-frequency coding variants in BAT2, HIST1H1E and BPIFB1 are associated with lung cancer risk in Chinese populations

2015 ◽  
Author(s):  
Guangfu Jin ◽  
Meng Zhu ◽  
Rong Yin ◽  
Wei Shen ◽  
Lin Xu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Low Frequency ◽  
Chinese Populations ◽  
Frequency Coding ◽  
Coding Variants

Abstract 2525: Low frequency TP53 mutations in airway epithelial cells serve as lung cancer risk biomarker

2021 ◽  
Author(s):  
Daniel J. Craig ◽  
Erin L. Crawford ◽  
Pierre P. Massion ◽  
Thomas Morrison ◽  
James C. Willey
Keyword(s):  
Lung Cancer ◽  
Epithelial Cells ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Low Frequency ◽  
Airway Epithelial Cells ◽  
Airway Epithelial ◽  
Tp53 Mutations

CYP1A1 and GSTM1 polymorphisms and lung cancer risk in Chinese populations: A meta-analysis

Lung Cancer ◽  
2008 ◽  
Vol 59 (2) ◽  
pp. 155-163 ◽  
Author(s):  
Xiuquan Shi ◽  
Suhua Zhou ◽  
Zhongxu Wang ◽  
Zongcan Zhou ◽  
Zengzhen Wang
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Meta Analysis ◽  
Chinese Populations

XRCC1 polymorphisms and lung cancer risk in Chinese populations: A meta-analysis

Lung Cancer ◽  
2009 ◽  
Vol 65 (3) ◽  
pp. 268-273 ◽  
Author(s):  
Huilie Zheng ◽  
Zhongxu Wang ◽  
Xiuquan Shi ◽  
Zengzhen Wang
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Meta Analysis ◽  
Chinese Populations

Variations in HSPA1B at 6p21.3 Are Associated with Lung Cancer Risk and Prognosis in Chinese Populations

2011 ◽  
Vol 71 (24) ◽  
pp. 7576-7586 ◽  
Author(s):  
Huan Guo ◽  
Qifei Deng ◽  
Chen Wu ◽  
Lingmin Hu ◽  
Sheng Wei ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Chinese Populations

scholarly journals Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk

2021 ◽  
Author(s):  
Yafang Li ◽  
Xiangjun Xiao ◽  
Jianrong Li ◽  
Jinyoung Byun ◽  
Chao Cheng ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Molecular Basis ◽  
Lung Cancer Risk ◽  
Interaction Analysis ◽  
Low Frequency ◽  
Cancer Development ◽  
Men And Women ◽  
Genome Wide ◽  
Sex Disparity

Abstract There is growing evidence showing that sex disparity in lung cancer risk cannot be fully explained by sex differences in smoking behavior, implying existence of genetic and molecular basis for sex disparity in lung cancer development. However, the information about sex dimorphism in lung cancer risk is quite limited despite the great success in lung cancer association studies. By adopting a stringent two-stage analysis strategy, we performed a genome-wide gene-sex interaction analysis using genotype from a lung cancer cohort including ~ 47,000 individuals with European ancestry. Three low-frequency variants (minor allele frequency < 0.05), rs17662871 (OR=0.71, p=4.29x10-8); rs79942605 (OR=2.17, p=2.81x10-8); and rs208908 (OR=0.70, p=4.54x10-8), were identified with different risk effect of lung cancer between men and women. Further eQTL and functional annotation analysis suggested rs208908 affect lung cancer risk through differential regulation of CXADR (Coxsackie Virus And Adenovirus Receptor) gene expression in lung tissues between men and women. Our study is one of the first studies to provide novel insights about the genetic and molecular basis for sex disparity in lung cancer development.

scholarly journals Genetic Variants on Chromosome 15q25 Associated with Lung Cancer Risk in Chinese Populations

2009 ◽  
Vol 69 (12) ◽  
pp. 5065-5072 ◽  
Author(s):  
Chen Wu ◽  
Zhibin Hu ◽  
Dianke Yu ◽  
Liming Huang ◽  
Guangfu Jin ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Genetic Variants ◽  
Lung Cancer Risk ◽  
Chinese Populations

Early Mortality in Patients with Lung Cancer: Risk Factors for Death within 30 Days or 60 Days of Initial Diagnosis

2019 ◽  
Author(s):  
A Tufman ◽  
S Schneiderbauer ◽  
D Kauffmann-Guerrero ◽  
F Manapov ◽  
C Schneider ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Early Mortality ◽  
Initial Diagnosis ◽  
Cancer Risk Factors
Sign in / Sign up

Export Citation Format

Share Document