Abstract PO-062: Why drug and radiation combination synergism or antagonism can be quantitatively determined with the mass-action law based pharmacodynamics equation, algorithm and computer simulation

Author(s):  
Ting-Chao Chou
Ecology ◽  
1964 ◽  
Vol 45 (3) ◽  
pp. 502-507 ◽  
Author(s):  
David Garfinkel ◽  
Richard Sack

1973 ◽  
Vol 30 (02) ◽  
pp. 381-392
Author(s):  
M Martin ◽  

SummaryThe plasminogen-streptokinase complex called “activator” was present in diluted plasma in the form of a largely dissociated mixture. More than ⅞ of the streptokinase and plasminogen molecules were available for further activator formation.The activator is probably a dissociated complex of the formulaStreptokinase + Plasminogen ⇄ Activator.The fact that an increase in activator concentration by x times is obtained by multiplying either the streptokinase content by the factor y or the plasminogen concentration by the same factor y would point to a kinetic effect along the lines of the mass action law.


2021 ◽  
Vol 22 ◽  
pp. 103922
Author(s):  
A.N. Gorban

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