Utility of the Peripheral Blood Basophil Histamine Release Test in the Diagnosis of Hen’s Egg, Cow’s Milk, and Wheat Allergy in Children

2011 ◽  
Vol 155 (s1) ◽  
pp. 96-103 ◽  
Author(s):  
Sakura Sato ◽  
Hiroshi Tachimoto ◽  
Akinori Shukuya ◽  
Mika Ogata ◽  
Takatsugu Komata ◽  
...  
2011 ◽  
Vol 127 (2) ◽  
pp. AB147-AB147
Author(s):  
T. Utsunomiya ◽  
T. Imai ◽  
N. Yanagida ◽  
S. Sato ◽  
T. Komata ◽  
...  
Keyword(s):  

2021 ◽  
Vol 42 (5) ◽  
pp. e135-e144 ◽  
Author(s):  
Metin Aydogan ◽  
Erdem Topal ◽  
Nalan Yakıcı ◽  
Hazal Cansu Acar ◽  
Zeynep Hızlı Demirkale ◽  
...  

Background: Several factors that increase the risk of severe food-induced anaphylaxis have been identified. Objective: We aimed to determine the demographic, etiologic, and clinical features of food-induced anaphylaxis in early childhood and also any other factors associated with severe anaphylaxis. Methods: We carried out a medical chart review of anaphylaxis cases from 16 pediatric allergy and immunology centers in Turkey. Results: The data of 227 patients with 266 food-induced anaphylaxis episodes were included in the study. The median (interquartile range) age of the first anaphylaxis episode was 9 months (6‐18 months); 160 of these patients were boys (70.5%). The anaphylaxis episodes were mild in 75 cases (28.2%), moderate in 154 cases (57.9%), and severe in 37 cases (13.9%). The most frequent food allergens involved were cow's milk (47.4%), nuts (16.7%), and hen's egg (15.8%). Epinephrine was administered in only 98 (36.8%) of these anaphylaxis episodes. A logistic regression analysis revealed two statistically significant factors that were independently associated with severe anaphylaxis: the presence of angioedema and hoarseness during the anaphylactic episode. Urticaria was observed less frequently in patients who developed hypotension. In addition, confusion and syncope were associated with 25.9- and 44.6-fold increases, respectively, in the risk of concomitant hypotension. Conclusion: Cow's milk, nuts, and hen's egg caused the majority of mild and moderate-to-severe anaphylaxis episodes. The presence of angioedema and hoarseness in any patient who presents with a history of food-induced anaphylaxis should alert clinicians that the reaction may be severe. In addition, the presence of confusion, syncope, or stridor probably indicates concomitant hypotension.


2011 ◽  
Vol 70 (6) ◽  
pp. 549-554 ◽  
Author(s):  
Immacolata Vocca ◽  
Roberto Berni Canani ◽  
Alessandra Camarca ◽  
Serena Ruotolo ◽  
Rita Nocerino ◽  
...  

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