scholarly journals A Case of Generalized Acanthosis Nigricans with Positive Lupus Erythematosus-Related Autoantibodies and Antimicrosomal Antibody: Autoimmune Acanthosis Nigricans

2012 ◽  
Vol 4 (1) ◽  
pp. 85-91 ◽  
Author(s):  
Y. Kondo ◽  
N. Umegaki ◽  
M. Terao ◽  
H. Murota ◽  
T. Kimura ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Acanthosis Nigricans ◽  
Antimicrosomal Antibody

Systemic lupus erythematosus with acanthosis nigricans, hyperpigmentation, and insulin receptor antibody

Lupus ◽  
1997 ◽  
Vol 6 (3) ◽  
pp. 275-278 ◽  
Author(s):  
J.S. Baird ◽  
J.L. Johnson ◽  
D. Elliott-Mills ◽  
L.M. Opas
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Insulin Receptor ◽  
Lupus Erythematosus ◽  
Acanthosis Nigricans ◽  
Systemic Lupus ◽  
Receptor Antibody

scholarly journals Diffuse Esophageal Squamous Papillomatosis: A Rare Disease Associated with Acanthosis Nigricans and Tripe Palms

2020 ◽  
Vol 14 (3) ◽  
pp. 702-706
Author(s):  
Tanyaporn Chantarojanasiri ◽  
Arunluk Buranathawornsom ◽  
Apichet Sirinawasatien
Keyword(s):  
Lupus Erythematosus ◽  
Acanthosis Nigricans ◽  
Hyperplastic Polyp ◽  
Gastrointestinal Malignancy ◽  
Gi Endoscopy ◽  
Thai Woman ◽  
Long Term Follow Up ◽  
Upper Gi Endoscopy

Acanthosis nigricans with tripe palms is one of the skin manifestations of systemic conditions, as well as internal malignancy. There have been reports of this paraneoplastic condition’s association with orocutaneous papillomatosis, but investigations into its relationship with diffuse esophageal papillomatosis are scarce. We report a case of acanthosis nigricans with tripe palms that was associated with diffuse esophageal squamous papillomatosis. A 40-year-old Thai woman with underlying systemic lupus erythematosus and secondary Sjögren’s syndrome, who was recently diagnosed with acanthosis nigricans and tripe palms was investigated for occult gastrointestinal malignancy. An upper GI endoscopy revealed diffuse squamous papilloma along the entire esophagus and lower GI endoscopy revealed one pedunculated hyperplastic polyp 1 cm in size at the sigmoid colon. Long-term follow-up is needed to reassure these coexisting conditions belonging to benign systemic diseases without hidden malignancy.

Organized Intraglomerular Deposits in NZB Mouse Disease

1971 ◽  
Vol 29 ◽  
pp. 544-545
Author(s):  
Francis R. Comerford ◽  
Alan S. Cohen
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Antinuclear Antibodies ◽  
Human Systemic Lupus Erythematosus ◽  
Systemic Lupus ◽  
Glomerular Lesion ◽  
Ultrastructural Studies ◽  
Dense Deposits ◽  
Experimental Nephritis ◽  
Glomerular Lesions

Mice of the inbred NZB strain develop a spontaneous disease characterized by autoimmune hemolytic anemia, positive lupus erythematosus cell tests and antinuclear antibodies and nephritis. This disease is analogous to human systemic lupus erythematosus. In ultrastructural studies of the glomerular lesion in NZB mice, intraglomerular dense deposits in mesangial, subepithelial and subendothelial locations were described. In common with the findings in many examples of human and experimental nephritis, including many cases of human lupus nephritis, these deposits were amorphous or slightly granular in appearance with no definable substructure.We have recently observed structured deposits in the glomeruli of NZB mice. They were uncommon and were found in older animals with severe glomerular lesions by morphologic criteria. They were seen most commonly as extracellular elements in subendothelial and mesangial regions. The deposits ranged up to 3 microns in greatest dimension and were often adjacent to deposits of lipid-like round particles of 30 to 250 millimicrons in diameter and with amorphous dense deposits.

“Subcortical” cognitive impairment in patients with systemic lupus erythematosus

2000 ◽  
Vol 6 (7) ◽  
pp. 821-825 ◽  
Author(s):  
ELIZABETH LERITZ ◽  
JASON BRANDT ◽  
MELISSA MINOR ◽  
FRANCES REIS-JENSEN ◽  
MICHELLE PETRI
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Cognitive Impairment ◽  
Lupus Erythematosus ◽  
Systemic Lupus

Subacute disseminated lupus erythematosus

1969 ◽  
Vol 100 (5) ◽  
pp. 653-654
Author(s):  
E. H. Mandel
Keyword(s):  
Lupus Erythematosus

Lupus erythematosus panniculitis (profundus)

1971 ◽  
Vol 103 (3) ◽  
pp. 231-242 ◽  
Author(s):  
D. L. Tuffanelli
Keyword(s):  
Lupus Erythematosus ◽  
Lupus Erythematosus Panniculitis
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