‘En Face' Optical Coherence Tomography with Enhanced Depth Imaging of Different Patterns of the Choroidal Neovascular Network in Age-Related Macular Degeneration

2014 ◽  
pp. 93-100
Author(s):  
Gabriel Coscas ◽  
Florence Coscas
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Depth Imaging ◽  
Age Related ◽  
En Face

Choroidal vascularity index determined by binarization of enhanced depth imaging optical coherence tomography images in eyes with intermediate age-related macular degeneration

2020 ◽  
Vol 30 (6) ◽  
pp. 1512-1518
Author(s):  
Sehnaz Ozcaliskan ◽  
Sevcan Balci ◽  
Nursal Melda Yenerel
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Structural Changes ◽  
Age Related Macular Degeneration ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Depth Imaging ◽  
Age Related ◽  
Luminal Area ◽  
Imaging Optical Coherence Tomography

Purpose To evaluate choroidal structural changes in patients with intermediate age-related macular degeneration using choroidal vascularity index. Methods The eyes of patients with intermediate age-related macular degeneration and controls were evaluated with enhanced depth imaging optical coherence tomography images. Subfoveal choroidal area was segmented into luminal area and stromal area by the binarization technique on enhanced depth imaging optical coherence tomography images using ImageJ software. Choroidal vascularity index was defined as the ratio of luminal area to total circumscribed subfoveal choroidal area. Results Fifty-seven eyes with intermediate age-related macular degeneration and 60 healthy control eyes were included in the study. The choroidal vascularity index was computed as 59.53% ± 4.9% in the intermediate age-related macular degeneration group and as 62.7% ± 4.3% in the control group ( p = 0.002). Patients with age-related macular degeneration showed significantly lower values of stromal area and higher values of luminal area compared to control subjects (0.51 ± 0.22 vs 0.87 ± 0.21, p < 0.001 and 0.74 ± 0.22 vs 0.52 ± 0.18, p < 0.001, respectively). Conclusion Eyes with intermediate age-related macular degeneration demonstrated reduced choroidal vascularity index compared to healthy eyes. Choroidal vascularity index seems to be a potential non-invasive quantitative method for studying structural changes of the choroid in patients with intermediate age-related macular degeneration.

En face swept-source optical coherence tomography in neovascular age-related macular degeneration

2015 ◽  
Vol 99 (9) ◽  
pp. 1260-1267 ◽  
Author(s):  
Ignacio Flores-Moreno ◽  
Luis Arias-Barquet ◽  
Marcos J Rubio-Caso ◽  
José M Ruiz-Moreno ◽  
Jay S Duker ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Swept Source ◽  
Age Related ◽  
En Face

scholarly journals Classification of Exudative Age-Related Macular Degeneration With Pachyvessels on En Face Swept-Source Optical Coherence Tomography

2017 ◽  
Vol 58 (2) ◽  
pp. 1054 ◽  
Author(s):  
Danny Siu-Chun Ng ◽  
Malini Bakthavatsalam ◽  
Frank Hiu-Ping Lai ◽  
Carol Yim-Lui Cheung ◽  
Gemmy Chu-Ming Cheung ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Swept Source ◽  
Age Related ◽  
En Face

scholarly journals Evaluation of the clinical utility of optical coherence tomography angiography in age-related macular degeneration

2020 ◽  
pp. bjophthalmol-2020-316622
Author(s):  
Melina Cavichini ◽  
Kunny C Dans ◽  
Mahima Jhingan ◽  
Manuel J Amador-Patarroyo ◽  
Shyamanga Borooah ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Optical Coherence Tomography Angiography ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Fluorescein Angiogram ◽  
Age Related ◽  
Specificity And Sensitivity ◽  
En Face ◽  
Dry Amd

Background/AimsTo evaluate the ability of optical coherence tomography angiography (OCTA) to identify the presence or absence of choroidal neovascularisation (CNV) and CNV activity in age-related macular degeneration (AMD).MethodsClinical parameters, fundus fluorescein angiogram and spectral-domain optical coherence tomography (SD-OCT) were used as the gold standard to determine disease activity. OCTA imaging was performed on the same day and was graded by two masked retina specialists for the presence or absence of CNV. Traditional multimodal imaging and OCTA findings were compared.ResultsOne hundred and fifty-two eyes of 106 patients with AMD were retrospectively reviewed. Of these, 59 eyes had wet AMD and 93 had dry AMD with high-risk drusen. OCTA had 85.4% and 79.3% specificity and sensitivity, respectively, in determining the presence or absence of CNV. OCTA was 69.5% accurate in determining active CNV. False positives and negatives were 21.6% and 8.0%, respectively.ConclusionsThis study suggests that en-face OCTA images allow a moderate ability to identify CNV and that OCTA alone is weak at recognising active CNV requiring treatment in AMD.

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