Gabapentin and Amitriptilin Treatment toward Living Quality of Post Ischemic Stroke Patients with Neurophaty Pain

2015 ◽  
Vol 4 (4) ◽  
pp. 250
Author(s):  
Pinasti Utami ◽  
Zulies Ikawati ◽  
Setyaningsih Setyaningsih

Stroke becomes a significant problem for developing countries. In Indonesia the data show its incidences 234 per 100.000 people, and around 2 - 8 % stroke patients experiencing cerebrovascular session will get neurophaty pain. It happens because of sensoric deviation after stroke, so the brain does not completely send information to the body correctly. Patients experiencing neurophaty pain are able to face decreasing living quality as the effect of long term painful disturbance. Therefore, it is important to maintain the patients’ living quality. The aim of the study is to investigate the comparison of using gabapentin and amitriptilin toward living quality of ischemic stroke patients with neurophaty pain in the hospitals in Jogja. The method used in this study was quasi experimental with consequtive sampling. The study was conducted on 22nd of April-31st of Juli 2013 by involving 23 patients in gabapentin group and 18 patientsin amitriptilin group that would be evaluated during 1 month. Living quality was assessed by Brief Pain Inventory (BPI) in week 0 and week 4. The result of the study showed that the use of gabapentin and amitriptilin in 4 weeks showed the increase of living quality represented by decreasing the score based on BPI questioner 1.67±0.78 and 1.37±0.80 with p-value>0.05 meaning that there was no significant difference. It can be concluded the comparison of using gabapentin and amitriptilin in post ischemic stroke patient with neuropathy pain not significantly increase the quality of in the hospitals in Jogja.

2015 ◽  
Vol 4 (4) ◽  
pp. 250
Author(s):  
Pinasti Utami ◽  
Zulies Ikawati ◽  
Setyaningsih Setyaningsih

Stroke becomes a significant problem for developing countries. In Indonesia the data show its incidences 234 per 100.000 people, and around 2 - 8 % stroke patients experiencing cerebrovascular session will get neurophaty pain. It happens because of sensoric deviation after stroke, so the brain does not completely send information to the body correctly. Patients experiencing neurophaty pain are able to face decreasing living quality as the effect of long term painful disturbance. Therefore, it is important to maintain the patients’ living quality. The aim of the study is to investigate the comparison of using gabapentin and amitriptilin toward living quality of ischemic stroke patients with neurophaty pain in the hospitals in Jogja. The method used in this study was quasi experimental with consequtive sampling. The study was conducted on 22nd of April-31st of Juli 2013 by involving 23 patients in gabapentin group and 18 patientsin amitriptilin group that would be evaluated during 1 month. Living quality was assessed by Brief Pain Inventory (BPI) in week 0 and week 4. The result of the study showed that the use of gabapentin and amitriptilin in 4 weeks showed the increase of living quality represented by decreasing the score based on BPI questioner 1.67±0.78 and 1.37±0.80 with p-value>0.05 meaning that there was no significant difference. It can be concluded the comparison of using gabapentin and amitriptilin in post ischemic stroke patient with neuropathy pain not significantly increase the quality of in the hospitals in Jogja.


Neurosurgery ◽  
2020 ◽  
Vol 88 (1) ◽  
pp. 131-139 ◽  
Author(s):  
Tao Du ◽  
Bing Ni ◽  
Wei Shu ◽  
Yongsheng Hu ◽  
Hongwei Zhu ◽  
...  

Abstract BACKGROUND Microvascular decompression (MVD) and vagoglossopharyngeal rhizotomy (VGR) are effective treatment for glossopharyngeal neuralgia (GN). However, surgical choice is controversial due to the need to maximize pain relief and reduce complications. OBJECTIVE To retrospectively compare safety, efficacy, long-term quality of life (QOL), and global impression of change following MVD and VGR for treatment of GN. METHODS Patient database reviews and telephone surveys were conducted to assess baseline characteristics and long-term outcomes. The effects of pain and complications on QOL were assessed using Brief Pain Inventory-Facial (BPI-Facial) questionnaire. Complication tolerance and surgery satisfaction were sorted using the global impression of change survey. RESULTS Of 87 patients with GN, 63 underwent MVD alone, 20 underwent VGR alone, and 4 underwent VGR following a failed MVD. The long-term rate of pain relief was slightly, but not significantly, lower following MVD than VGR (83.6% vs 91.7%, P = .528). However, long-term complications occurred much more frequently following VGR (3.0% vs 50.0%, P < .001). The BPI-Facial, which evaluates pain and complications, showed that MVD had better postoperative QOL than VGR (P < .001). However, 91.7% of patients who underwent VGR experienced no or mild complications. There was no significant difference in the overall satisfaction rates between the groups (83.3% vs 83.6%, P > .99). CONCLUSION Although VGR resulted in lower postoperative QOL due to a high complication rate, most of these complications were mild. The overall satisfaction rates for the 2 surgeries were similar.


2021 ◽  
Vol 45 (5) ◽  
pp. 359-367
Author(s):  
Jin A Yoon ◽  
Yong-Il Shin ◽  
Deog Young Kim ◽  
Min Kyun Sohn ◽  
Jongmin Lee ◽  
...  

Objective To investigate long-term and serial functional outcomes in ischemic stroke patients without diabetes with post-stroke hyperglycemia.Methods The Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) is a large, multi-center, prospective cohort study of stroke patients admitted to participating hospitals in nine areas of Korea. From KOSCO, ischemic stroke patients without diabetes were recruited and divided into two groups: patients without diabetes without (n=779) and with post-stroke hyperglycemia (n=223). Post-stroke hyperglycemia was defined as a glucose level >8 mmol/L. Functional assessments were performed 7 days and 3, 6, and 12 months after stroke onset.Results There were no significant differences in baseline characteristics between the groups, except in the age of onset and smoking. Analysis of the linear correlation between the initial National Institutes of Health Stroke Scale (NIHSS) score and glucose level showed no significant difference. Among our functional assessments, NIHSS, Fugl-Meyer Assessment (affected side), Functional Ambulatory Category, modified Rankin Scale, and Korean Mini-Mental State Examination (K-MMSE) showed statistically significant improvements in each group. All functional improvements except K-MMSE were significantly higher in patients without post-stroke hyperglycemia at 7 days and 3, 6, and 12 months.Conclusion The glucose level of ischemic stroke patients without diabetes had no significant correlation with the initial NIHSS score. The long-term effects of stress hyperglycemia showed worse functional outcomes in ischemic stroke patients without diabetes with post-stroke hyperglycemia.


2018 ◽  
Vol 6 (1) ◽  
pp. 38-48
Author(s):  
Gina Dwi Anggraini ◽  
Septiyanti Septiyanti ◽  
Dahrizal Dahrizal

Stroke is lost brain function caused by stop his blood supply to the brain. As a result of the disruption of oxygen to the brain needs can occur the clinical manifestations included the weakness of some or all of the body limbs, one of over ekstremities so that the patient could not doing the activity because of the limbs weakness and they needs exercise for preveting disability. Objective is Know the effect of Range Of Motion (ROM) Spherical Grip on muscle strenght of upper extremity on stroke patients. The research used quasi-experimental with pretest and posttest with control group. The population in this study is all stroke patients in the neurological specialist RSUD dr. M. Yunus of Bengkulu City. The Sampling technique used is Cluster Sampling. The number of sample is 32. Instruments used for manual muscle testing. Test for normality using the Kolmogorov-Smirnov and analysis techniques using Wilcoxon Signed Ranks Test  and Mann-Whitney with 95% confidence level (  = 0,05). Muscle strenght of the finger mean in the control group 2,44 increase to 2,63 with the difference 0,1875. In the intervention group mean 2,44 increase to 3,13 with the difference 0,6875. Muscle strenght of the wrist mean in the control group 2,38 increase to 2,56 with the difference 0,1875. In the intervention group mean 2,25 increase to 3,00 with the difference 0,75. The result obtained p-value 0,011 finger hand and p-value 0,027 wrist. Exercise Range Of Motion (ROM) Spherical Grip is effective in increase muscle strenght of over extremities on stroke patients.


2020 ◽  
Vol 6 (4) ◽  
pp. 435-441
Author(s):  
Nora Veri ◽  
Nila Suci Ramadhani ◽  
Alchalidi Alchalidi

ABSTRACT Background: Emesis gravidarum can get worse into hyperemesis gravidarum which causes the body to become weaker, paler, and the frequency of urination decreases. As a result, decreased body fluids and hemoconcentration of blood can cause tissue damage. Non pharmacological treatment is very important because it reduces the pharmacological effects that appear in pregnant women. The herbal therapy that has been proven to be beneficial is the administration of peppermint, but research on the effects of Pamelo fruit related to nausea and vomiting in pregnant women is still rare.Objective: To determine the comparison of the effectiveness of peppermint and Pomelo orange on the intensity of nausea and vomiting in pregnant womenMethods: The research design was a quasi experimental study with a pretest posttest control group design approach. The number of samples was 24 pregnant women who were grouped into 3 groups.Results: The average intensity of nausea and vomiting in the peppermint group at pretest was 2.38 and decreased at posttest to 1 with P-value 0.004. The intensity of nausea and vomiting in the Pomelo group at pretest was 6.38, falling to 1.75 at posttest with P-value 0.000. The result of further test showed that there was no significant difference in the intensity of nausea and vomiting between the two groups with Sig. 0.428.Conclusion: Peppermint and pomelo are effective in reducing the intensity of nausea and vomiting in trimester I pregnant women.Suggestion : This research needs to be refined by enlarging the research sample and measuring the intensity of nausea and vomiting can be done every day during the study considering that this study only measured twice the number of 24 respondents. Keywords : Nausea, Vomiting, Pregnancy, Peppermint, Pomelo ABSTRAK Latar Belakang : Emesis gravidarum dapat bertambah berat menjadi hiperemesis gravidarum yang mengakibatkan tubuh semakin lemah, pucat, dan frekuensi buang air kecil menurun. Akibatnya cairan tubuh berkurang dan hemokonsentrasi darah yang dapat menimbulkan kerusakan jaringan. Pengobatan non farmakolgis sangat penting karena mengurangi efek farmakologis yang muncul pada ibu hamil. Terapi herbal yang sudah terbukti bermanfaat adalah pemberian peppermint, namun penelitian efek buah Pamelo yang berkaitan dengan mual muntah pada ibu hamil masih jarang.Tujuan Penelitian : Untuk mengetahui  perbandingan efektifitas pemberian peppermint dan Jeruk Pomelo terhadap intensitas  mual dan  muntah pada ibu hamilMetode Penelitian : Rancangan penelitian ini adalah quasi experimental dengan pendekatan pretest posttest control group design. Jumlah sampel  adalah sebanyak 24 orang ibu hamil yang dikelompokkan kedalam 3 kelompok.Hasil Penelitian : Rata-rata intensitas mual muntah pada kelompok peppermint saat pretest adalah 2,38 dan menurun pada saat posttest menjadi 1 dengan P-value 0,004. Intensitas mual muntah kelompok Pomelo pada pretest adalah 6.38 turun menjadi 1,75 pada saat posttest dengan P-value 0,000. Hasil uji lanjut didapatkan tidak ada perbedaan bermakna intensitas mual muntah antara kedua kelompok dengan Sig. 0,428.Kesimpulan : Pemberian Peppermint dan pomelo efektif dalam menurunkan intensitas mual dan muntah pada ibu hamil trimester I.Saran : Penelitian ini perlu disempurnakan dengan memperbesar sampel penelitian dan pengukuran intensitas mual muntah dapat dilakukan setiap hari selama penelitian mengingat penelitian ini hanya mengukur sebanyak dua kali pada 24 responden. Kata kunci : Mual, Muntah, Kehamilan, Peppermint, Pomelo 


2022 ◽  
Vol 8 (1) ◽  
pp. 30-34
Author(s):  
Fildza Intan Rizkia ◽  
Chandra Calista ◽  
Suryani Gunadharma ◽  
Asep Nugraha Hermawan ◽  
Lisda Amalia ◽  
...  

Background: Cognitive impairment is a common condition that may affect up to 50% of stroke patients. Post stroke cognitive impairment is associated with reduced quality of life, which may increase the number of dependency. Recurrent stroke may happen in approximately 25% patients and they have higher rates of cognitive impairment. Objective: The aim of this study is to examine the comparison of cognitive function between first ischemic stroke and recurrent ischemic stroke patients in Hasan Sadikin Hospital, Bandung. Methods: This study is a retrospective, cross-sectional study using the data recruited between the year 2012 - 2016 at the Department of Neurology at the Hasan Sadikin Hospital Bandung. The data collected in this study were demographic data, including age, level of education, and residence, and the clinical data as well. Cognitive function was assessed using Mini-Mental State Examination (MMSE). The comparison between the cognitive function between both groups were analyzed using the Mann-Whitney U test. Results: There were 428 subjects eligible for this study, with 207 subjects categorized as first ischemic stroke group and 221 subjects categorized as recurrent ischemic stroke group. There was a statistically significant difference in MMSE scores between the first ischemic stroke patients (24.90 ± 4.64) and recurrent ischemic stroke patients (22.85 ± 4.64 ) with a p value of 0.002. Conclusion: Recurrent ischemic stroke patients had lower MMSE scores than the first ischemic stroke patients. Clinicians should be more aware in detecting early cognitive impairment in stroke patients and in preventing the incidence of recurrent stroke.


2020 ◽  
Vol 4 (1) ◽  
pp. 178-186
Author(s):  
Defia Roza ◽  
Sila Dewi Anggreni ◽  
Heppi Sasmita ◽  
Yessi Fadriyanti ◽  
Nova Yanti

This study aimed to determine the effectiveness of SEFT interventions in improving the quality of life of HIV / AIDS patients in Padang City. The design of this study was a Quasi-experimental design with one group pretest and posttest. This study found that the average quality of life of HIV patients before SEFT administration was 97.07, and the average rate of life of HIV patients after SEFT administration was 102.6. It can be seen that the mean difference between before and after SEFT action is 5.57 with a standard deviation of 6.98. The statistical test results obtained p-value = 0.011. In conclusion, there is a significant difference between the quality of life of HIV patients before and after SEFT treatment.   Keywords: HIV, Quality of Life, SEFT


2019 ◽  
Vol 7 (5) ◽  
Author(s):  
Yuli Mulyanti Soenar ◽  
Deswani Kasim

An understanding of reproductive health in the elderly, especially women, becomes so important because there are so many changes that occur when women enter old age. Decreasing reproductive health in women occurs when women enter menopause. For this reason, it is necessary to provide appropriate information to the elderly regarding the health of their reproductive system, to avoid health problems that threaten the overall condition of the body. This study aims to determine the effect of reproductive health education in the elderly. The research method used was quasi-experimental with non-randomized pretest-posttest group control design. The number of samples in this study was 62 people consisting of 32 people in the intervention group and 30 people in the control group. Data analysis in this study with paired t-test and independent. The results showed that there was a significant difference in knowledge of the elderly between the intervention group and the control group after the intervention (p-value = 0,000), so there were significant differences in the attitudes of Keywords: reproductive health education, elderly, knowledge, attitudes the elderly between the intervention and control groups, after the intervention (p = 0.008). The conclusion is that there is an influence of reproductive health education in the elderly on the knowledge and attitudes.


Author(s):  
Darwel ◽  
R Selvia ◽  
F Fadillah ◽  
Mahaza ◽  
E Zicof

Compost can be used to reduce waste, it formed naturally, but it will take a long time, around 6-12 months. Bioactivators accelerate composting process; one of them is a solution of LMO (Local Microorganism) coconut pulp. The purpose of this study to determine the effectiveness of LMO coconut pulp for the composting time. The method in this research is quasi-experimental. This study consists of 3 treatments with 5 replications. Treatment 1 composting with the addition of LMO coconut pulp 50,000 ppm; treatment 2 composting with the addition of LMO coconut pulp 100,000 ppm; treatment 3 composting with the addition of LMO coconut pulp 200,000 ppm. The materials used in this study are vegetables and sawdust and the composting process carried out aerobically. From the observations, the average time to compile with LMO coconut pulp 50,000 ppm is 21.00 (21 days), 100,000 ppm 18.60 (19 days) and 200,000 ppm 18.20 (18 days). Based on the ANOVA test, the p value is 0.0001 (p <0.05) which means that H0 rejected, that there is a significant difference in composting time using LMO coconut pulp 50,000 ppm, 100,000 ppm, and 200,000 ppm. The most significant difference is between compost with LMO coconut pulp 50,000 ppm and compost with LMO coconut pulp 200,000 ppm. It is recommended for the further researchers using other types of waste, and test the quality of compost produced especially C/N compost. The community can use coconut pulp as a bioactivator in accelerating the composting process. Int. J. Agril. Res. Innov. Tech. 11(1): 109-116, June 2021


Sign in / Sign up

Export Citation Format

Share Document