scholarly journals Letter Regarding Article by Lazar et al, “Tight Glycemic Control in Diabetic Coronary Artery Bypass Graft Patients Improves Perioperative Outcomes and Decreases Recurrent Ischemic Events”

Circulation ◽  
2004 ◽  
Vol 110 (20) ◽  
Author(s):  
George Carvalho ◽  
Thomas Schricker
2019 ◽  
Vol 107 (2) ◽  
pp. 477-484 ◽  
Author(s):  
Michael P. Robich ◽  
Alexander Iribarne ◽  
Bruce J. Leavitt ◽  
David J. Malenka ◽  
Reed D. Quinn ◽  
...  

2011 ◽  
Vol 254 (3) ◽  
pp. 458-464 ◽  
Author(s):  
Harold L. Lazar ◽  
Marie M. McDonnell ◽  
Stuart Chipkin ◽  
Carmel Fitzgerald ◽  
Caleb Bliss ◽  
...  

2010 ◽  
Vol 44 (5) ◽  
pp. 289-294 ◽  
Author(s):  
Margarita Beresnevaitė ◽  
Rimantas Benetis ◽  
Graeme J. Taylor ◽  
Kristina Jurėnienė ◽  
Šarūnas Kinduris ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Harold L. Lazar

Hyperglycemia, which occurs in the perioperative period during cardiac surgery, has been shown to be associated with increased morbidity and mortality. The management of perioperative hyperglycemia during coronary artery bypass graft surgery and all cardiac surgical procedures has been the focus of intensive study in recent years. This report will paper the pathophysiology responsible for the detrimental effects of perioperative hyperglycemia during cardiac surgery, show how continuous insulin infusions in the perioperative period have improved outcomes, and discuss the results of trials designed to determine what level of a glycemic control is necessary to achieve optimal clinical outcomes.


Author(s):  
Christopher Cao ◽  
David H. Tian ◽  
Su C. Ang ◽  
Sheen Peeceeyen ◽  
James Allan ◽  
...  

Objective The radial artery has been demonstrated to provide superior long-term patency outcomes compared with saphenous veins for selected patients who undergo coronary artery bypass graft surgery. Recently, endoscopic radial artery harvesting has been popularized to improve cosmetic and perioperative outcomes. However, concerns have been raised regarding the effects on long-term survival and graft patency of this relatively novel technique. The present meta-analysis aimed to assess the safety and the efficacy of endoscopic radial artery harvesting versus the conventional open approach. Methods A systematic review of the current literature was performed on five electronic databases. All comparative studies on endoscopic versus open radial artery harvesting were included for analysis. Primary endpoints included mortality and recurrent myocardial infarction. Secondary endpoints included graft patency, wound infection, hematoma formation, and paresthesia. Results Twelve studies involving 3314 patients were included for meta-analysis according to predefined selection criteria. There were no statistically significant differences in overall mortality, recurrent myocardial infarction, or graft patency between the two surgical techniques. However, patients who underwent endoscopic harvesting were found to have significantly lower incidences of wound infection, hematoma formation, and paresthesia. Conclusions Current literature on endoscopic harvesting of the radial artery for coronary artery bypass graft surgery is limited by relatively short follow-up periods as well as differences in patient selection and surgical techniques. In addition, there are currently no randomized controlled trials to provide robust clinical data. However, the available evidence suggests that the endoscopic approach is associated with superior perioperative outcomes without clear evidence demonstrating compromised patency or survival outcomes.


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