Abstract 13282: Patients With Peripheral Artery Disease Perceptions of an Ankle Foot Orthosis: A Comparison by Physical Activity Level

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Danae Dinkel ◽  
Mahdi Hassan ◽  
Holly Despiegelaere ◽  
JASON Johanning ◽  
Iraklis I Pipinos ◽  
...  

Introduction: Peripheral Artery Disease (PAD) restricts blood flow to the legs. Its most common manifestation is claudication, a severe impairment of physical activity produced by ischemia-related leg pain and tiredness during walking. We are conducting a trial to evaluate the possibility that an ankle foot orthosis could reduce claudication symptoms and increase the physical activity of patients with PAD. The perceptions of patients with PAD on wearing the ankle foot orthosis and how they vary by baseline physical activity level are unknown. Therefore, this study explored the perceptions of patients with PAD while using an ankle foot orthosis and if these perceptions varied by level of physical activity. Hypothesis: We hypothesize that those who are more physically active will perceive more benefits as a result of using the ankle foot orthosis. Methods: Participants (n=21) wore an ankle foot orthosis for 3 months. Baseline median step count was used to divide patients into high (n=10) or low (n=11) active groups. Semi-structured interviews were conducted at midpoint and post. Data were analyzed using a summative content analysis. Results: Patients averaged 3233 ± 1523 steps/day with a median of 3137 steps/day at baseline. 45% of participants’ initial responses described a positive perception of their time wearing the ankle foot orthosis. 71.4% of participants reported an overall positive impact of wearing the ankle foot orthosis, primarily being able to walk further. Comparison by baseline physical activity level revealed 36.4% of participants with low physical activity reported seeing improvements in daily tasks (walking in the grocery store) versus 10% of those with high physical activity. Conclusions: In conclusion, our interview data demonstrate that perceived quality of physical activity in patients with PAD improved with the use of the ankle foot orthosis. Contrary to our hypothesis, minimal differences in perceptions of ankle foot orthosis use were found between patients with low versus high baseline physical activity levels.

2020 ◽  
Vol 52 (7S) ◽  
pp. 1005-1005
Author(s):  
Mahdi Hassan ◽  
Danae M. Dinkel ◽  
Holly DeSpiegelaere ◽  
Jason M. Johanning ◽  
Iraklis I. Pipinos ◽  
...  

Author(s):  
Ayisha Z. Bashir ◽  
Danae M. Dinkel ◽  
Ganesh M. Bapat ◽  
Holly Despiegelaere ◽  
Mahdi Hassan ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Sumiko Shiba ◽  
Akiko Shiba ◽  
Atsutoshi Hatada

Objectives. Peripheral artery disease (PAD) is a significant prognostic marker of poor long-term survival due to limited physical activity associated with various functional problems, such as intermittent claudication. A physically active lifestyle has the potential to modify peripheral artery risk factors and promote general health. While low daily physical activity levels have been recognized in the population of PAD, the exact level has yet to be quantified due to lack of research. The aim of the present study was to compare physical activity level (PAL) and time spent at activities of different intensity levels between patients with PAD and healthy individuals. The study subjects were 10 patients with PAD and 10 age-matched healthy control subjects. We measured the time spent at light, moderate, or vigorous physical activity using triaxial accelerometer and calculated PAL. Intermittent claudication onset distance and maximum walking distance were defined as the distance walked at which the subject first reported leg pain and the distance at which the subject was unable to continue walking because of leg pain, respectively. Results. Our results showed (i) lower PAL in patients with PAD compared with the controls; (ii) while there was no significant difference in the high-intensity activity between the two groups, the light- and moderate-intensity activities of the PAD group were significantly lower than the controls, the time spent at moderate-intensity activity was approximately 50% less; and (iii) among patients with PAD, low PAL did not correlate directly with intermittent claudication. Conclusions. PAD patients limit the amount of their physical activity, especially light and moderate intensities. Our study highlights the importance of spending more time walking in daily life.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 211-211
Author(s):  
Sara Myers ◽  
Danae Dinkel ◽  
Mahdi Hassan ◽  
Holly Despiegelaere ◽  
Jason Johanning ◽  
...  

Abstract Peripheral artery disease (PAD) impacts over 8.5 million Americans and the prevalence of PAD increases with age. PAD restricts blood flow to the leg and its most common manifestation is claudication, a severe impairment of walking produced by ischemia-related, leg pain during exercise. An ankle foot orthosis (AFO) could improve these symptoms. To understand the potential impact of AFO usage, it is critical to determine wearability of the device in patients with PAD. The purpose of this study was to monitor wear time of an AFO and explore perceptions of the device. Participants (n=14) with PAD and claudication wore an AFO for three months. An accelerometer was placed directly on the AFO for 7 days and participants completed semi-structured interviews at midpoint (1.5 months) and post intervention (3 months). Based on accelerometer data at midpoint participants wore the AFO for an average of 4.9±2.3 out of 7 days and for an average of 7.5±4.2 hours each day. At post, participants wore the AFO for an average of 4.8±2.2 days for an average of 7.4±4.6 hours per day. In the interviews, almost all participants noted multiple barriers to wearing the AFO such as difficulty putting the AFO on and off, using stairs, walking on uneven ground, and driving. Our study found that participants wore the AFO ~7 hours/day but experienced barriers which may have limited their wear outside of these monitoring periods suggesting patients would wear an assistive device if design could be improved to address barriers.


2013 ◽  
Vol 2013 ◽  
pp. 1-7
Author(s):  
Andrew W. Gardner ◽  
Petar Alaupovic ◽  
Donald E. Parker ◽  
Polly S. Montgomery ◽  
Omar L. Esponda ◽  
...  

Apolipoprotein B is a stronger predictor of myocardial infarction than LDL cholesterol, and it is inversely related to physical activity and modifiable with exercise training. As such, apolipoprotein measures may be of particular relevance for subjects with PAD and claudication. We compared plasma apolipoprotein profiles in 29 subjects with peripheral artery disease (PAD) and intermittent claudication and in 39 control subjects. Furthermore, we compared the plasma apolipoprotein profiles of subjects with PAD either treated (n=17) or untreated (n=12) with statin medications. For the apolipoprotein subparticle analyses, subjects with PAD had higher age-adjusted Lp-B:C (P<0.05) and lower values of Lp-A-I:A-II (P<0.05) than controls. The PAD group taking statins had lower age-adjusted values for apoB (P<0.05), Lp-A-II:B:C:D:E (P<0.05), Lp-B:E + Lp-B:C:E (P<0.05), Lp-B:C (P<0.05), and Lp-A-I (P<0.05) than the untreated PAD group. Subjects with PAD have impaired apolipoprotein profiles than controls, characterized by Lp-B:C and Lp-A-I:A-II. Furthermore, subjects with PAD on statin medications have a more favorable risk profile, particularly noted in multiple apolipoprotein subparticles. The efficacy of statin therapy to improve cardiovascular risk appears more evident in the apolipoprotein sub-particle profile than in the more traditional lipid profile of subjects with PAD and claudication. This trial is registered with ClinicalTrials.govNCT00618670.


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