scholarly journals Myocardial Effects of Aldosterone Antagonism in Heart Failure With Preserved Ejection Fraction

Author(s):  
Adam K. McDiarmid ◽  
Peter P. Swoboda ◽  
Bara Erhayiem ◽  
Katrina A. Bounford ◽  
Petra Bijsterveld ◽  
...  
2016 ◽  
Vol 68 (17) ◽  
pp. 1823-1834 ◽  
Author(s):  
Wojciech Kosmala ◽  
Aleksandra Rojek ◽  
Monika Przewlocka-Kosmala ◽  
Leah Wright ◽  
Andrzej Mysiak ◽  
...  

2008 ◽  
Vol 7 ◽  
pp. 62-63
Author(s):  
J NUNEZ ◽  
L MAINAR ◽  
G MINANA ◽  
R ROBLES ◽  
J SANCHIS ◽  
...  

2010 ◽  
Vol 6 (2) ◽  
pp. 33 ◽  
Author(s):  
Christopher R deFilippi ◽  
G Michael Felker ◽  
◽  

For many with heart failure, including the elderly and those with a preserved ejection fraction, both risk stratification and treatment are challenging. For these large populations and others there is increasing recognition of the role of cardiac fibrosis in the pathophysiology of heart failure. Galectin-3 is a novel biomarker of fibrosis and cardiac remodelling that represents an intriguing link between inflammation and fibrosis. In this article we review the biology of galectin-3, recent clinical research and its application in the management of heart failure patients.


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