scholarly journals Significance of Exercise‐Related Ventricular Arrhythmias in Patients With Brugada Syndrome

2020 ◽  
Vol 9 (23) ◽  
Author(s):  
Hiroshi Morita ◽  
Saori T. Asada ◽  
Masakazu Miyamoto ◽  
Yoshimasa Morimoto ◽  
Tomonari Kimura ◽  
...  
Keyword(s):  
High Risk ◽  
Exercise Test ◽  
Brugada Syndrome ◽  
Treadmill Exercise ◽  
Recovery Phase ◽  
Early Recovery ◽  
Treadmill Exercise Test ◽  
St Segment ◽  
Early Recovery Phase

Background Sinus tachycardia during exercise attenuates ST‐segment elevation in patients with Brugada syndrome, whereas ST‐segment augmentation after an exercise test is a high‐risk sign. Some patients have premature ventricular contractions (PVCs) related to exercise, but the significance of exercise‐related PVCs in patients with Brugada syndrome is still unknown. The objective of this study was to determine the significance of exercise‐related PVCs for predicting occurrence of ventricular fibrillation (VF) in patients with Brugada syndrome. Methods and Results The subjects were 307 patients with Brugada syndrome who performed a treadmill exercise test. We evaluated the occurrence of PVCs at rest, during exercise and at the peak of exercise, and during recovery after exercise (0–5 minutes). We followed the patients for 92±68 months and evaluated the occurrence of VF. PVCs occurred in 82 patients (27%) at the time of treadmill exercise test: PVCs appeared at rest in 14 patients (4%), during exercise in 60 patients (20%), immediately after exercise (0–1.5 minutes) in 28 patients (9%), early after exercise (1.5–3 minutes) in 18 patients (6%), and late after exercise (3–5 minutes) in 12 patients (4%). Thirty patients experienced VF during follow‐up. Multivariable analysis including symptoms, spontaneous type 1 ECG, and PVCs in the early recovery phase showed that these factors were independently associated with VF events during follow‐up. Conclusions PVCs early after an exercise test are associated with future occurrence of VF events. Rebound of vagal nerve activity at the early recovery phase would promote ST‐segment augmentation and PVCs in high‐risk patients with Brugada syndrome.

Abstract 2142: Diagnostic and Prognostic Value of Augmented ST-Segment Elevation at Exercise Testing in Patients with Brugada Syndrome

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Hisaki Makimoto ◽  
Eiichiro Nakagawa ◽  
Hiroshi Takaki ◽  
Kenichiro Yamagata ◽  
Hiro Kawata ◽  
...  
Keyword(s):  
Exercise Testing ◽  
Brugada Syndrome ◽  
Recovery Phase ◽  
Peak Exercise ◽  
Early Recovery ◽  
St Segment Elevation ◽  
St Segment ◽  
History Of ◽  
Diagnostic And Prognostic Value ◽  
Early Recovery Phase

Background : It has been reported that ST-segment elevation was augmented at early recovery phase or at peak exercise during exercise testing in some patients with Brugada syndrome (BrS), but its diagnostic and prognostic value has not fully been clarified. Methods : Treadmill exercise testing (TMT) was conducted in 93 patients (pts) with BrS (22 documented VF, 31 syncope alone, and 40 asymptomatic; 91 males, 46±14 years) and 22 healthy control subjects (20 males, 48±14 years, 11 with incomplete right bundle branch block (RBBB) and 4 with complete RBBB). Results : The augmentation of ST-segment elevation ≥0.05mV in V1-V3 leads compared with that before exercise was observed at early recovery phase (1– 4 minutes at recovery phase) in 32 BrS pts (34%, Group1), at peak exercise in 8 BrS pts (9%, Group 2), but not in either the remaining 53 BrS pts (57%, Group 3) or 22 control subjects. There were no significant differences among the 3 BrS groups in the baseline clinical (age, gender, family history of sudden death, SCN5A mutation), electrocardiographic (PR, QRS duration, QTc interval and ST amplitude), and electrophysiologic (AH, HV interval, and VF induction) variables except for the positive ratio of signal averaged ECG (87%, 48%, 63%; P= 0.001). No significant difference was observed in the proportion of previous cardiac events (VF/syncope/asymptomatic; 6/12/14, 0/3/5, 16/16/21, respectively for Group 1, 2, and 3). During 76.0, 74.8, and 52.0 months follow-up, VF occurred in 12/32 (38%) pts of Group1, 0/8 (0 %) pts of Group2, and 10/53 (19%) pts of Group3. Augmentation of ST-segment elevation at early recovery phase was a significant and an independent predictor for subsequent VF occurrence (12/32 (38%) in Group1 vs. 10/61 (16%) in Group2 and 3; hazard ratio [HR]= 1.68; P=0.014), especially in 31 pts with a history of syncope alone (6/12 (50%) in Group1 vs. 1/19 (5%) in Group2 and 3; HR=3.44; P=0.004). Conclusions : Our data suggest that augmentation of ST-segment elevation at early recovery phase during exercise testing can be a predictor of poor prognosis in patients with Brugada syndrome, especially in those with a history of syncope alone.

Abstract 208: Follow-up Study in Kawasaki Disease By Treadmill Exercise Test And Echocardiography

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Sin-Ae Park ◽  
Kichul Park ◽  
Jee Won Park
Keyword(s):  
Heart Disease ◽  
Coronary Artery ◽  
Kawasaki Disease ◽  
Ischemic Heart Disease ◽  
Exercise Test ◽  
Treadmill Exercise ◽  
Treadmill Exercise Test ◽  
Long Term Follow Up

Kawasaki disease (KD) may result in coronary aneurysm formation and increased risk of cardiovascular complications such as ischemic heart disease. Therefore, the early detection, non-invasive monitoring and long-term follow-up of myocardial ischemia are essential. This study sought to determine the ischemic heart disease by treadmill exercise test and two-dimensional echocardiography. Three hundred and four patients with a history of KD from 1995 to 2005 were retrospectively analyzed. Among them fifty patients who agree with the study underwent exercise test and 2D-echocardiography. The patients were followed for 11.6 years(8 to 17) from disease onset. The coronary artery ectasia regressed in 21 patients. No stenotic lesion could be found in the coronary artery in follow-up echocardiography. And no significant ischemic changes were detected. There is no evidence of persisting coronary ectasia and dysfunction of cardiac perfusion in patients with previous KD in this study. However, these patients should be counselled to avoid potential risk factors for other complication such as atherosclerosis and long term follow up is needed into adult life.

PP-234 PRECORDIAL ST-SEGMENT ELEVATION TRIGGERED BY TREADMILL EXERCISE TEST IN A SEDENTARY PATIENT

2012 ◽  
Vol 155 ◽  
pp. S180
Author(s):  
U. Canpolat ◽  
H. Yorgun ◽  
M. Dural ◽  
E. Hüsrevzade ◽  
L. Şahiner ◽  
...  
Keyword(s):  
Exercise Test ◽  
Treadmill Exercise ◽  
Treadmill Exercise Test ◽  
St Segment Elevation ◽  
St Segment

scholarly journals Abnormal rise of the systolic blood pressure during recovery phase from a treadmill exercise test.

1988 ◽  
Vol 77 (9) ◽  
pp. 1383-1387
Author(s):  
Shozo NEZUO ◽  
Shin-ichiro TADAOKA ◽  
Masatoshi NAKAO ◽  
Kouichi HASEGAWA ◽  
Satoshi KAKUMAE ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Exercise Test ◽  
Treadmill Exercise ◽  
Recovery Phase ◽  
Treadmill Exercise Test

scholarly journals Precordial ST-segment elevation triggered by treadmill exercise test in a sedentary patient

2013 ◽  
Vol 8 (1) ◽  
pp. e60-e62
Author(s):  
Uğur Canpolat ◽  
Hikmet Yorgun ◽  
Kudret Aytemir ◽  
Ali Oto
Keyword(s):  
Exercise Test ◽  
Treadmill Exercise ◽  
Treadmill Exercise Test ◽  
St Segment Elevation ◽  
St Segment

scholarly journals ST-segment fluctuation induced by treadmill exercise test in patients with angina pectoris

1982 ◽  
Vol 2 (2) ◽  
pp. 168-174
Author(s):  
Hidetsugu Asanoi ◽  
Masao Kuboki ◽  
Machiko Yamamoto ◽  
Tadanori Aizawa ◽  
Junichi Fujii ◽  
...  
Keyword(s):  
Angina Pectoris ◽  
Exercise Test ◽  
Treadmill Exercise ◽  
Treadmill Exercise Test ◽  
St Segment
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