Abstract WP272: Left Atrial Enlargement is Associated With Neuroworsening and Worse Short-Term Outcomes in Acute Ischemic Stroke

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Alyana A Samai ◽  
Karen Albright ◽  
Digvijaya Navalkele ◽  
Carmel Alemayehu ◽  
Sheryl Martin-Schild
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Left Atrial ◽  
Short Term ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

scholarly journals Relation Between Left Atrial Enlargement and Stroke Subtypes in Acute Ischemic Stroke Patients

2013 ◽  
Vol 15 (3) ◽  
pp. 131 ◽  
Author(s):  
Hye-Young Shin ◽  
In-Hye Jeong ◽  
Chang-Ki Kang ◽  
Dong-Jin Shin ◽  
Hyeon-Mi Park ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Left Atrial ◽  
Stroke Patients ◽  
Left Atrial Enlargement ◽  
Stroke Subtypes ◽  
Atrial Enlargement

Abstract WP201: Left Atrial Enlargement Predicts 3-Month Outcome in Acute Embolic Stroke

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Seung Min Kim
Keyword(s):  
Ischemic Stroke ◽  
Clinical Outcome ◽  
Acute Ischemic Stroke ◽  
Left Atrial ◽  
Embolic Stroke ◽  
Long Term Outcome ◽  
Left Atrial Enlargement ◽  
Poor Outcome ◽  
Atrial Enlargement

Introduction: Although previous studies have shown that the role of left atrial enlargement (LAE) on ischemic stroke, the association with long-term clinical outcome is less clear. We hypothesized that LAE might be associated with long-term outcome in acute ischemic stroke most likely related to embolism (cryptogenic and cardioembolism). Methods: This was a prospective study for patients with acute ischemic stroke as documented by MRI. Echocardiographic LAE was categorized as normal, mild, moderate and severe. Poor outcome was defined as modified Rankin Scale at 3-month of 2-6. The association between LAE and clinical outcome was explored using multivariate analysis adjusting for demographics and other clinical variables. Results: Of 178 patients enrolled, 87 (48.9%) had no LAE, whereas 50 (28.1%) had mild, 30 (16.9%) had moderate and 11 (6.1%) had severe LAE. Infarct volume on MRI was larger in severe LAE (36.53±30.11 cm 3 ) followed by moderate (32.81±28.84 cm 3 ), mild (13.4±16.53 cm 3 ), and normal (11.9±13.16 cm 3 ; p<0.001). At the 3-month follow-up, the poor outcomes were more common in moderate to severe (67%), followed by mild (51%), and normal LAE (46%; p<0.001). In multivariable models adjusted for confounders including heart failure, moderate-to severe LAE compared to normal LAE was associated with poor clinical outcome (odds ratio 1.54, confidence interval 1.04-4.55). Mild LAE was not associated with poor outcome. Conclusions: Our present study shows that LAE is an independent predictor of 3-month clinical outcomes in acute embolic stroke.

Left Atrial Enlargement and Anticoagulation Status in Patients with Acute Ischemic Stroke and Atrial Fibrillation

2018 ◽  
Vol 27 (1) ◽  
pp. 192-197 ◽  
Author(s):  
Katarina Dakay ◽  
Andrew D. Chang ◽  
Morgan Hemendinger ◽  
Shawna Cutting ◽  
Ryan A. McTaggart ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Left Atrial ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

Abstract TMP112: Left Atrial Enlargement is Associated With Anticoagulation Failure in Patients With Acute Ischemic Stroke and Atrial Fibrillation

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Katarina Dakay ◽  
Andrew D Chang ◽  
Morgan Hemendinger ◽  
Shawna M Cutting ◽  
Ryan A McTaggart ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Left Atrial ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

scholarly journals Associated Factors with Left Atrial Enlargement in Patients with Acute Ischemic Stroke

2018 ◽  
Vol 57 (4) ◽  
pp. 627-627
Author(s):  
Özcan Başaran ◽  
Volkan Doğan ◽  
Gökhan Ergün ◽  
Murat Biteker
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Left Atrial ◽  
Associated Factors ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

scholarly journals Left Atrial Enlargement and Risk of Ischemic Stroke in Elderly Treated Hypertensive Patients

2014 ◽  
Vol 27 (9) ◽  
pp. 1179-1184 ◽  
Author(s):  
S. D. Pierdomenico ◽  
A. M. Pierdomenico ◽  
S. Di Carlo ◽  
R. Di Tommaso ◽  
F. Cuccurullo
Keyword(s):  
Ischemic Stroke ◽  
Left Atrial ◽  
Hypertensive Patients ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

Abstract WP236: Left Atrial Enlargement and Cryptogenic Stroke

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Prasanna Tadi ◽  
Mayra MontalvoPerero ◽  
Pranav M Reddy ◽  
Shadi Yaghi
Keyword(s):  
Ischemic Stroke ◽  
Left Atrial ◽  
Small Vessel Disease ◽  
Cryptogenic Stroke ◽  
Control Group ◽  
Left Atrial Enlargement ◽  
Vessel Disease ◽  
Extensive Evaluation ◽  
2D Echocardiography ◽  
Atrial Enlargement

Introduction: Despite extensive evaluation, no definite cause is identified in 30-40% of ischemic stroke patients. Biomarkers of atrial dysfunction or “cardiopathy” have been shown to be associated with ischemic stroke risk, a relationship independent of atrial fibrillation. Our aim was to determine the association between left atrial enlargement (LAE) and cryptogenic stroke. Methods: This was a single center retrospective study using the stoke registry of a comprehensive stroke center. The study was approved by the institution board review. We reviewed medical records of patients admitted with acute ischemic stroke between December 1 st , 2013 and August 31 st , 2015 for demographic data (age and sex) and risk factors (hypertension, hyperlipidemia, coronary artery disease, prior stroke, congestive heart failure, and current smoking status). A vascular neurologist determined stroke subtype and cryptogenic stroke was defined based on the embolic stroke of unknown source (ESUS) criteria. Patients with cardioembolic stroke were excluded and the control group included small vessel disease, large vessel disease and other causes including hypercoagulable states, dissection and drug use. The primary predictor was left atrial (LA) size from 2D echocardiography and LA size was categorized as normal, mild LAE, moderate LAE, and severe LAE using the American Society of Echocardiography Recommendations for chamber quantification. Results: We identified 236 patients with ischemic stroke; 85 cryptogenic stroke and 151 non-cryptogenic stroke. For the entirety of the group, the mean age was 67 years with 45% males. Patients with cryptogenic stroke were more likely to have moderate to severe LAE when compared to patients with known non-cardioembolic etiology (12.8% vs. 3.2%, p = 0.0061). Conclusion: Moderate to severe left atrial enlargement, a biomarker of atrial cardiopathy or dysfunction, is more prevalent in patients with cryptogenic stroke than non-cardioembolic strokes of known etiology. Clinical trials are needed to study anticoagulation vs. antiplatelet therapy in patients with cryptogenic stroke and evidence of moderate to severe LAE.

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