Quinine inhibits production of tumor necrosis factor-alpha from human alveolar macrophages.

1994 ◽  
Vol 10 (5) ◽  
pp. 514-520 ◽  
Author(s):  
N Maruyama ◽  
Y Kakuta ◽  
K Yamauchi ◽  
Y Ohkawara ◽  
T Aizawa ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis Factor Alpha ◽  
Alveolar Macrophages ◽  
Tumor Necrosis ◽  
Necrosis Factor Alpha ◽  
Human Alveolar Macrophages ◽  
Factor Alpha ◽  
Necrosis Factor

scholarly journals Effects of Tumor Necrosis Factor Alpha on Sin Nombre Virus Infection In Vitro

2000 ◽  
Vol 74 (24) ◽  
pp. 11966-11971 ◽  
Author(s):  
Svetlana F. Khaiboullina ◽  
Dale M. Netski ◽  
Peter Krumpe ◽  
Stephen C. St. Jeor
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis Factor Alpha ◽  
Alveolar Macrophages ◽  
Tumor Necrosis ◽  
Sin Nombre Virus ◽  
Necrosis Factor Alpha ◽  
Tnf Α ◽  
Human Alveolar Macrophages ◽  
Factor Alpha ◽  
Necrosis Factor

ABSTRACT Previous data indicate that immune mechanisms may be involved in developing capillary leakage during Sin Nombre virus (SNV) infection. Therefore, we investigated production of tumor necrosis factor alpha (TNF-α) by human alveolar macrophages and human umbilical vein endothelial cells (HUVEC) after infection with SNV. In addition, we examined the effect of TNF-α on HUVEC monolayer leakage. Our results reveal that although TNF-α decreases accumulation of viral nucleoproteins, TNF-α levels do not change in SNV-infected cells. In addition, supernatants from SNV-infected human alveolar macrophages did not cause a significant increase in endothelial monolayer permeability.

Dyscoordinate Expression of Tumor Necrosis Factor-alpha by Human Blood Monocytes and Alveolar Macrophages

1989 ◽  
Vol 139 (4) ◽  
pp. 1010-1016 ◽  
Author(s):  
Elizabeth A. Rich ◽  
James R. Panuska ◽  
Robert S. Wallis ◽  
Christopher B. Wolf ◽  
Michelle L. Leonard ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis Factor Alpha ◽  
Human Blood ◽  
Alveolar Macrophages ◽  
Tumor Necrosis ◽  
Blood Monocytes ◽  
Necrosis Factor Alpha ◽  
Factor Alpha ◽  
Necrosis Factor
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