scholarly journals Saccadic latency in amblyopia

2016 ◽  
Vol 16 (5) ◽  
pp. 3 ◽  
Author(s):  
Suzanne P. McKee ◽  
Dennis M. Levi ◽  
Clifton M. Schor ◽  
J. Anthony Movshon
Keyword(s):  
1980 ◽  
Vol 20 (4) ◽  
pp. 329-339 ◽  
Author(s):  
P.E. Hallett ◽  
B.D. Adams
Keyword(s):  

2005 ◽  
Vol 93 (6) ◽  
pp. 3214-3223 ◽  
Author(s):  
Brian J. White ◽  
Karl R. Gegenfurtner ◽  
Dirk Kerzel

It has been suggested that the remote distractor effect is the result of nontarget stimulation of a central region representing a collicular fixation zone near the time of target onset. The distributed network of the cells responsible for this effect is believed to extend over a large area, responding to distractors ≤10 deg in the periphery. Several studies also implicate the superior colliculus as the substrate behind an inhibited saccadic response arising from a display change. We investigated this further by using a patch of pink noise of various sizes as a nontarget stimulus. We show that the onset of a small patch (2.3 × 2.3 deg) of centrally displayed pink noise can produce a significant increase in saccadic latency to a simultaneously presented peripheral Gabor target. In contrast, a large patch (36 × 36 deg) of pink noise did not increase latency despite the fact that it also stimulated the region representing the fixation zone. Furthermore, only the large patch of noise facilitated latency when presented before target onset. We also examined the effect of patch sizes between these two extremes and found a steady decrease in latency as patch size increased. This confirms that nontarget stimulation of the region representing the fixation zone near the time of target onset is not in itself sufficient to produce the increase in latency typically found with remote distractors. The results are consistent with the idea that only a spatially confined object leads to a discharge of collicular fixation neurons.


2020 ◽  
Vol 29 (12) ◽  
pp. 1635-1644
Author(s):  
Johan Lundin Kleberg ◽  
Matilda A. Frick ◽  
Karin C. Brocki

Abstract Attenuated baseline arousal has been hypothesized to underlie symptoms of attention deficit/hyperactivity disorder (ADHD). A behavioral signature of reduced baseline arousal is an increased beneficiary effect of warning signals in reaction tasks. This paradoxical effect is believed to be caused by a temporary increase in arousal induced by warning signals. In a preregistered study, we tested the hypothesis that children with high levels of ADHD symptoms would be hyperresponsive to warning signals in a well-established visual attention task (the gap/overlap paradigm). Previous studies using this task have found slower and more variable saccadic reaction times in children with ADHD compared to typically developing children, suggesting that these eye movement metrics are candidate biomarkers. We examined 71 children, of which 1/3 had a diagnosis of ADHD, using both dimensional analyses and group comparisons. Previously reported findings of reduced saccadic latency and increased latency variability were replicated. Importantly, saccadic latency was normalized by auditory warning signals. Analyses of pupil dilation, a physiological index of arousal and locus coeruleus-noradrenergic activity, confirmed that warning signals led to enhanced arousal. Our findings are novel and contribute to our understanding of arousal and attention in ADHD and have implications for treatment and interventions.


1996 ◽  
Vol 36 (19) ◽  
pp. 3195-3203 ◽  
Author(s):  
R.P. KALESNYKAS ◽  
P.E. HALLETT
Keyword(s):  

2015 ◽  
Vol 26 (1) ◽  
pp. 72-77 ◽  
Author(s):  
Olivia K. Faull ◽  
Josephine Robertson ◽  
Owen Thomas ◽  
Arthur R. Bradwell ◽  
Chrystalina A. Antoniades ◽  
...  
Keyword(s):  

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