scholarly journals Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity

Author(s):  
Fiona Bartoli ◽  
Marjolaine Debant ◽  
Eulashini Chuntharpursat-Bon ◽  
Elizabeth L. Evans ◽  
Katie E. Musialowski ◽  
...  
Author(s):  
Dewi Irawati Soeria Santoso ◽  
Hafizh Ahmad Boenyamin

Physical inactivity have been linked with many major non-communicable diseases and as many as 27.5% of adults globally are considered inactive. Physical activity has been proven to be beneficial in the prevention of many chronic diseases and may reduce the risk of premature death. High intensity interval training (HIIT) has been gaining popularity as a time-efficient alternative for regular exercise training. Current studies show that HIIT is more efficient in improving cardiorespiratory fitness, increasing insulin sensitivity and reducing blood pressure than moderate intensity continuous training (MICT). The advantage of HIIT in fat loss compared to MICT is still unclear, but HIIT might be more efficient in the obese population. The effect of HIIT on increasing aerobic fitness could be caused by increase in stroke volume due to the increase in cardiac contractility, capillary density and mitochondrial adaptation. Fat loss during HIIT could be caused by increased fat oxidation and elevated hormones that drive lipolysis and reduce appetite. While vigorous physical activity may transiently increase the risk of cardiac events. The effect of HIIT on increasing aerobic fitness could be caused by increase in stroke volume due to the increase in cardiac contractility, increased of capillary density and mitochondrial adaptation. While fat loss during HIIT could be caused by an increased fat oxidation, elevated hormones that drives lipolysis and reduces appetite. While vigorous physical activity may transiently increase the risk of cardiac event. High intensity interval training is generally safe even in the elderly population and in people with coronary heart disease.


2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mehran Ghahramani ◽  
Zeinab Razavi Majd

Context: The purpose of the present study was to investigate the context of research into the physiological roles of VEGF and the most important potential mechanisms that may lead to a temporary decrease in serum VEGF, as well as to perform a desirable conclusion and provide more relevant data from previous research. Methods: In this study, articles were searched in specialized databases and 40 related articles were selected based on inclusion and exclusion criteria. Then the effect of physical activity on VEGF and HIF-1 signaling was investigated. Results: Exercise and physical activity by stimulating and activating VEGF and HIF-1 signals may induce generating new arteries and angiogenesis. Conclusions: The present study showed that physical activity increases capillary density by increasing the level of diffusion, increasing the time of exchange between blood and tissue, and decreasing the oxygen diffusion distance. As a result, capillary dilatation and capacity increase and ultimately it improves athletes' performance.


JAMA ◽  
1966 ◽  
Vol 197 (11) ◽  
pp. 891-893 ◽  
Author(s):  
L. P. Novak

2008 ◽  
Vol 42 (8) ◽  
pp. 9
Author(s):  
MARY ANN MOON
Keyword(s):  

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