Age Dependency of Stimulated Salivary Flow Rate, pH, and Lactobacillus and Yeast Concentrations

1982 ◽  
Vol 61 (9) ◽  
pp. 1052-1055 ◽  
Author(s):  
T. Parvinen ◽  
M. Larmas
Keyword(s):  
Flow Rate ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Age Dependency

scholarly journals Effect of a newly developed pastille on the salivary flow rate in subjects with dry mouth symptoms: a randomized, controlled, monocentric clinical study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
S. Bielfeldt ◽  
D. Wilhelm ◽  
C. Neumeister ◽  
U. Schwantes ◽  
K. -P. Wilhelm
Keyword(s):  
Surface Tension ◽  
Flow Rate ◽  
Gum Arabic ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Dry Mouth ◽  
Main Ingredient ◽  
Control Product ◽  
Swallowing Problems ◽  
The Mean

Abstract Background Xerostomia is associated with several diseases and is a side effect of certain drugs, resulting from reduced saliva secretion. Often, aged and sometimes younger people suffer from (idiopathic) xerostomia. Chewing gum and sucking pastilles may relieve symptoms of xerostomia by increasing the salivary flow rate due to the mechanical effect of sucking and gustatory stimulation. Swallowing problems and the urge to cough or experiencing a tickling sensation in the throat might be alleviated through a reduction in dry mouth symptoms. We investigated whether a pastille containing four polysaccharides increased the salivary flow rate and relieved the symptoms of dry mouth. Methods Participating subjects with xerostomia were randomized into two equally balanced treatment groups. Subjects received the pastille on Day 1 and a control product (Parafilm®) on Day 3, or vice versa. Unstimulated saliva was collected every 2.5 min for 0–10 min. Stimulated saliva was collected after subjects sucked the pastille or the control product. The salivary flow rate was determined gravimetrically, and, in parallel, the feeling of dry mouth was assessed using a visual analog scale. Saliva surface tension was measured in pooled saliva samples (0–5 min of sampling). Additionally, in stimulated saliva from six subjects who sucked the pastille, the presence of the main ingredient—gum arabic—was examined by Raman spectroscopy. Results Chewing the pastille significantly increased the mean salivary flow rate by 8.03 g/10 min compared to the mean changes after chewing the control product (+ 3.71 g/10 min; p < 0.0001). The mean score of dry mouth was significantly alleviated by the pastille (− 19.9 ± 17.9 mm) compared to the control product (− 3.3 ± 18.1 mm). No difference between the two products was seen regarding the saliva surface tension. Gum arabic was present in the saliva of all investigated subjects for up to 10 min after sucking the pastille. Conclusions The pastille was well tolerated and effective in increasing the salivary flow rate and reducing mouth dryness after sucking. These results were in line with the detection of the main ingredient, gum arabic, in saliva for up to 10 min after sucking the pastille. Trial registration German Register Clinical Trials (Deutsches Register Klinische Studien, DRKS) DRKS-ID: DRKS00017393, Registered 29 May 2019, https://www.drks.de/drks_web/navigate.do?navigationId=trial. HTML&TRIAL_ID = DRKS00017393.

scholarly journals Salivary flow rate and the risk of cognitive impairment among Korean elders: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Minh-Tung Do ◽  
Huong Vu ◽  
Jong-Koo Lee ◽  
Sang-Min Park ◽  
Joung-Sik Son ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Flow Rate ◽  
Salivary Flow ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Salivary Flow Rate ◽  
Multivariable Logistic Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Denture Status

Abstract Background Salivary function has been suggested to be associated with cognitive impairment. However, the effect of salivary flow rate (SFR) on cognitive impairment remains unclear. This study aimed to investigate whether SFR is associated with cognitive impairment among Korean elders. Methods This cross-sectional study included 649 elders aged 65 and older in the Korean community-dwelling population. Cognitive impairment was assessed using the Mini-Mental Status Examination. Unstimulated SFR was measured and dichotomized. Denture status, age, sex, education level, smoking, drinking, diabetes, hypertension, and obesity were considered confounders. Multivariable logistic regression analysis was applied to assess the adjusted association. Stratified analysis by sex and denture status was performed to clarify the effect modification. Results Participants without cognitive impairment showed a higher SFR level than those with cognitive impairment (0.81 mL/min for non-cognitive impairment versus 0.52 mL/min for cognitive impairment, p < 0.001). After controlling for confounders, participants with low SFR (< 0.3 mL/min) were more likely to have cognitive impairment by 1.5 times than participants with normal SFR (odds ratio [OR] = 1.5, confidence interval [CI] = 1.05–2.10). The association of low SFR with cognitive impairment was higher in women and dentate participants: about 10% higher in women (OR = 1.63, CI = 1.07–2.50) and about 22% higher in dentate participants (OR = 1.82, CI = 1.41–2.90). Conclusions Salivary flow rate is independently associated with cognitive impairment among Korean elders. The association was modified in females and dentate elders. Physicians and dentists should consider low SFR and cognitive impairment as a risk factor between them in clinics.

scholarly journals Estimation of salivary glucose, salivary amylase, salivary total protein and salivary flow rate in diabetics in India

2010 ◽  
Vol 52 (3) ◽  
pp. 359-368 ◽  
Author(s):  
Arati S. Panchbhai ◽  
Shirish S. Degwekar ◽  
Rahul R. Bhowte
Keyword(s):  
Flow Rate ◽  
Total Protein ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Salivary Amylase

Su1102 - The Study of Swallowing Pattern, Gastroesophageal Reflux(GER) Characteristics in Pateints with Low (Xerostomia) and Normal Salivary Flow Rate

2018 ◽  
Vol 154 (6) ◽  
pp. S-488-S-489
Author(s):  
Jeerawat Maytapa ◽  
Kasidit Norasettkul ◽  
Sureeporn Jangsirikul ◽  
Tanisa Patcharatrakul ◽  
Sutep Gonlachanvit
Keyword(s):  
Gastroesophageal Reflux ◽  
Flow Rate ◽  
Salivary Flow ◽  
Salivary Flow Rate

Oral health status, salivary flow rate and salivary quality in children, adolescents and young adults with ADHD

2011 ◽  
Vol 56 (10) ◽  
pp. 1137-1141 ◽  
Author(s):  
Ariela Hidas ◽  
Avia Fux Noy ◽  
Noam Birman ◽  
Joseph Shapira ◽  
Israel Matot ◽  
...  
Keyword(s):  
Young Adults ◽  
Health Status ◽  
Oral Health ◽  
Flow Rate ◽  
Salivary Flow ◽  
Oral Health Status ◽  
Salivary Flow Rate ◽  
Adolescents And Young Adults
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