A Surgical Approach to Chordomas at the Base of the Skull

1982 ◽  
Vol 90 (2) ◽  
pp. 251-255 ◽  
Author(s):  
Robert H. Miller ◽  
Gayle E. Woodson ◽  
J. Gail Neely ◽  
Edward C. Murphy

Chordoma of the skull base has a poor prognosis because of the proximity of vital structures as well as the difficulty encountered in attempting complete surgical excision. This paper presents a case of massive recurrent chordoma involving the intracranial cavity, nasal cavity, and maxillary antrum. The tumor was debulked and decompressed via a transantral approach to the pterygomaxillary fossa and the base of the skull. This technique is recommended because it achieves immediate decompression and provides a space into which the inevitable regrowth of the tumor may extend.

2010 ◽  
Vol 128 (5) ◽  
pp. 302-305 ◽  
Author(s):  
Giulianno Molina de Melo ◽  
Gabrielle do Nascimento Holanda Gonçalves ◽  
Ricardo Antenor de Souza e Souza ◽  
Danilo Anunciatto Sguillar

CONTEXT: Neuroglial ectopia has been defined as a mass composed of differentiated neuroectodermal tissue isolated from the spinal canal or cranial cavity and remains rare. This lesion has to be considered in the differential diagnosis among newborn infants with classical symptoms of respiratory distress, neck mass and feeding difficulties. We present a rare case of extensive parapharyngeal and skull base neuroglial ectopia in 6-month-old girl who presented respiratory and feeding obstruction at birth. CASE REPORT: A six-month-old girl who presented upper respiratory and feeding obstruction at birth and was using tracheostomy and gastrostomy tubes was referred to our institution. Complete surgical excision of the mass consisted of a transcervical-transparotid approach with extension to the infratemporal fossa by means of a lateral transzygomatic incision, allowing preservation of all vital neurovascular structures. The anatomopathological examination showed a solid mass with nests of neural tissue, with some neurons embedded in poorly encapsulated fibrovascular stroma, without mitotic areas, and with presence of functioning choroid plexus in the immunohistochemistry assay. Neurovascular function was preserved, thus allowing postoperative decannulation and oral feeding. Despite the large size of the mass, the child has completed one year and six months of follow-up without complications or recurrence. Neuroglial ectopia needs to be considered in diagnosing airway obstruction among newborns. Surgical treatment is the best choice and should be performed on clinically stable patients. An algorithm to guide the differential diagnosis and improve the treatment was proposed.


1995 ◽  
Vol 31 (5) ◽  
pp. 439-447 ◽  
Author(s):  
GK King ◽  
KM Yates ◽  
PG Greenlee ◽  
KR Pierce ◽  
CR Ford ◽  
...  

Eight dogs and five cats with histopathologically confirmed fibrosarcomas were treated with Acemannan Immunostimulanta in combination with surgery and radiation therapy. These animals had recurring disease that had failed previous treatment, a poor prognosis for survival, or both. Following four to seven weekly acemannan treatments, tumor shrinkage occurred in four (greater than 50%; n = 2) of 12 animals, with tumors accessible to measurement. A notable increase in necrosis and inflammation was observed. Complete surgical excision was performed on all animals between the fourth and seventh week following initiation of acemannan therapy. Radiation therapy was instituted immediately after surgery. Acemannan treatments were continued monthly for one year. Seven of the 13 animals remain alive and tumor-free (range, 440+ to 603+ days) with a median survival time of 372 days. The data suggests that Acemannan Immunostimulant may be an effective adjunct to surgery and radiation therapy in the treatment of canine and feline fibrosarcomas.


2021 ◽  
pp. 014556132110079
Author(s):  
Xindi He ◽  
Ying Wang

Objectives: Neurilemmoma in the nasal cavity and paranasal sinuses is very rare. The study aimed to improve the understanding of neurilemmoma in the nasal cavity and paranasal sinuses. Materials and Methods: The clinical data of 10 patients with neurilemmoma in the nasal cavity and paranasal sinuses treated from January 2014 to June 2019 in our hospital were retrospectively studied. Results: There were 6 females and 4 males patients in our study. The mean age was 49.5 years (range 37-77 years), and the most common clinical symptom was unilateral nasal obstruction. The site of tumor included the nasal cavity, maxillary sinus, ethmoid sinus, and sphenoid sinus. There were 2 cases with malignant neurilemmoma. Nine patients underwent functional endoscopic sinus surgery (FESS); however, 1 patient underwent FESS combined with the lateral rhinotomy for complete resection of the tumor. Two patients with malignant neurilemmoma received postoperative radiotherapy. The mean follow-up was 3.82 years (range 2-7 years). There were no incidences of tumor recurrence during the study period. Conclusions: Neurilemmoma in the nasal cavity and paranasal sinuses is a mainly benign tumor. Complete surgical excision by FESS is the only treatment option for neurilemmoma in the nasal cavity and paranasal sinuses; while malignant neurilemmoma needs postoperative radiotherapy.


Author(s):  
Manish Munjal ◽  
Venus Tilavat ◽  
Porshia Rishi ◽  
Shubham Munjal ◽  
Harjinder Sidhu ◽  
...  

<p class="abstract">Intrinsic or extrinsic cysts are common maxillary antral lesions as there is close proximity between the maxillary antrum and maxillary teeth. Main stay of treatment is complete surgical excision. Endoscopic trans nasal middle meatus corridor and the canine fossa approach facilitate 360-degree access, resection and removal of cystic lesions of the maxillary antrum. Bimodal technique to treat maxillary cysts that have expanded into the maxillary sinus is discussed here.  </p>


2011 ◽  
Vol 125 (9) ◽  
pp. 973-977 ◽  
Author(s):  
C Delbrouck ◽  
M Chamiec ◽  
S Hassid ◽  
R Ghanooni

AbstractObjective:We report a pregnant patient with a rapidly growing mass within the nasal cavity, which required pre-operative super-selective embolisation and subsequent removal under general anaesthesia after childbirth. We also discuss the clinical, radiological and histological characteristics of lobular capillary haemangioma, and its treatment.Method:Case report and literature review.Results:Lobular capillary haemangioma is a benign lesion originating in the vascular tissue of skin, mucosa, muscles, glands and bone. These lesions grow rapidly. Nasal localisation is rare. Microtrauma and pregnancy are the most commonly proposed aetiological factors. Reported incidence during pregnancy ranges from less than 2 per cent to approximately 5 per cent. The management of a pregnant woman with such a lesion may be complex, and depends on the severity of symptoms and the status of the pregnancy. Complete surgical excision, with or without pre-operative embolisation, is the treatment of choice.Conclusion:This uncommon lesion should be considered in any pregnant patient with a mass in the mouth or nasal cavity.


2021 ◽  
pp. 014556132110345
Author(s):  
Jyun-Yi Liao ◽  
Herng-Sheng Lee ◽  
Bor-Hwang Kang

Schwannomas are rare slow-growing benign tumors arising from Schwann cells lining the nerve sheaths. Head and neck schwannomas account for about one-third of all cases, and only 4% of them arise from the sinonasal tract. Its diagnosis is based on histology and immunohistochemistry. Complete surgical excision is the most recommended treatment option, and endoscopic surgery has been widely performed in recent years. In this study, we presented a case of a 55-year-old female with schwannoma arising from the lateral wall of the nasal cavity, causing epistaxis and rhinorrhea. The patient underwent endoscopic excision with prompt resolution of symptoms. The reported cases of nasal cavity schwannoma were reviewed and summarized for educational purposes.


1976 ◽  
Vol 85 (3) ◽  
pp. 399-403 ◽  
Author(s):  
Lloyd R. Dropkin ◽  
Chik Kwun Tang ◽  
John R. Williams

A case of leiomyosarcoma of the nasal cavity and paranasal sinuses is presented along with a review of the medical literature. The clinicopathological aspects of this tumor are discussed. The mode of treatment is complete surgical excision with close follow-up due to its high rate of local recurrence. The long-term survival with recurrent disease in this case is unusual.


2013 ◽  
Vol 28 (1) ◽  
pp. 19-23
Author(s):  
Jonel Donn Leo S. Gloria

Objective:       To report a case of extragnathic sinonasal ameloblastoma and discuss its clinical features, approach to diagnosis, pathology, and management.   Methods: Study Design:             Case report Setting:                       Tertiary government university hospital Subject:                      One   Results:  A 40-year-old female consulted for a rapidly enlarging right intranasal mass of 4 months duration associated with recurrent profuse epistaxis and nasal obstruction.  Previous specimens of the mass were histopathologically interpreted as ameloblastoma versus craniopharyngioma.  Examination revealed a pink, fleshy, smooth right intranasal mass with associated nasomaxillary bulge and supero-lateral displacement of the right eye.  Computed tomography (CT) scan and magnetic resonance imaging (MRI) of the nasal cavity and paranasal sinuses demonstrated a soft-tissue density occupying the entire nasal cavity with erosion but no invasion of the maxillary sinus and no intracranial extension despite erosion of the skull base.  The mass was completely excised via lateral rhinotomy and the final histopathologic diagnosis was ameloblastoma.   Conclusion:    Extragnathic sinonasal ameloblastoma is a benign but locally aggressive variant of ameloblastoma involving the nasal cavity and/or paranasal sinuses often mimicking malignant tumors.  Diagnosis is primarily based on histopathology but radiologic and intraoperative findings help distinguish it from differentials.  Complete surgical excision remains the treatment of choice, and coupled with good follow up, may improve the prognosis of patients.   Keywords: sinonasal ameloblastoma, extragnathic, craniopharyngioma


1993 ◽  
Vol 72 (12) ◽  
pp. 811-815 ◽  
Author(s):  
Thomas O. Willcox ◽  
Seth I. Rosenberg ◽  
Steven D. Handler

Neurofibromas of the larynx are an uncommon component of neurofibromatosis, but should be considered in the differential diagnosis of patients with a submucosal supraglottic mass. Complete surgical excision is the treatment of choice; however, incomplete excision may be preferable to aggressive debilitatingsurgery. Plexiform neurofibromadiffers from non-plexiform neurofibroma in that it is poorly circumscribed and highly infiltrative. Tracheostomymaybe necessary. Sarcomatous degeneration is reportedandcarries a poor prognosis.


2017 ◽  
Vol 7 (28) ◽  
pp. 235-239
Author(s):  
Vlad Budu ◽  
Tatiana Decuseara ◽  
Andreea Nicoleta Costache ◽  
Loredana Ghiuzan ◽  
Monica Hodor ◽  
...  

AbstractNasal meningoencephaloceles are rare findings, represented by protrusions of intracranial contents into the nasal cavity. They present as unilateral masses, and commonly determine unilateral nasal obstruction, rhinorrhea and non-characteristic headaches.We present the case of a 34-year-old patient diagnosed with a posttraumatic transethmoidal meningoencephalocele. The patient presented with unilateral nasal obstruction, mild headache and episodic watery rhinorrhea. The treatment was endoscopic endonasal surgical excision and repair of the skull base defect, in a mixt ENT-neurosurgical team. Patient follow-up showed no remaining mass or symptoms and normal closure of the skull base defect.


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