Intravascular Malignant T-cell Lymphoma (Malignant Angioendotheliomatosis) in a Cat

1997 ◽  
Vol 34 (3) ◽  
pp. 247-250 ◽  
Author(s):  
J.-M. Lapointe ◽  
R. J. Higgins ◽  
G. D. Kortz ◽  
C. S. Bailey ◽  
P. F. Moore
Keyword(s):  
Arterial Wall ◽  
Cell Lymphoma ◽  
Vascular Wall ◽  
Cerebrospinal Fluid Analysis ◽  
Parietal Lobes ◽  
Fluid Analysis ◽  
History Of ◽  
Complete Thrombosis ◽  
The Right ◽  
Wall Invasion

A 7-year-old spayed female Siamese cat was presented with a 7-day history of ataxia, circling to the right, and involuntary micturition and defecation. Cerebrospinal fluid analysis showed increased protein content and relative eosinophilia. At necropsy, there was flattening of the cerebral cortical gyri of the right frontal and parietal lobes, and both kidneys had multiple wedge-shaped cortical indentations. Histologically, the cerebral cortex contained several extensive malacic foci, and the kidneys had multifocal parenchymal degeneration and atrophy. There was multifocal partial to complete thrombosis of renal interlobar arteries and of the right middle cerebral artery and meningeal branches; these thrombi contained large anaplastic round cells, which often invaded the arterial wall. Many smaller vessels within the kidneys and brain were occluded with clusters of similar cells, without thrombosis or vascular wall invasion. The neoplastic round cells had immunohistochemical staining properties of T lymphocytes.

Haemiballism/haemichorea: an atypical presentation of ischaemic stroke

2021 ◽  
Vol 14 (6) ◽  
pp. e240439
Author(s):  
Raman Nohria ◽  
Stacey Bennett ◽  
Yasmin Ali O'Keefe
Keyword(s):  
Brain Mri ◽  
Acute Onset ◽  
Cerebral Peduncle ◽  
Atypical Presentation ◽  
Cerebrospinal Fluid Analysis ◽  
Medication Therapy ◽  
Fluid Analysis ◽  
Ct Head ◽  
The Right ◽  
Distressing Condition

A 76-year-old man was admitted to the hospital with acute onset of involuntary movements of the left side of his body. His neurological examination revealed he was oriented only to himself, and aforementioned movements of his left arm and leg. CT head demonstrated old infarcts in his right aspect of his pons and basal ganglia. Cerebrospinal fluid analysis was unremarkable. He initially had a normal blood glucose with an elevated anion gap and elevated creatine kinase. Brain MRI showed a small lacunar-type ischaemic infarct within the anteromedial aspect of the right cerebral peduncle, which localised to his haemiballism. To prevent worsening rhabdomyolysis associated with his haemiballism, the primary team initiated both tetrabenazine and diazepam. His movements improved after 1 week of medication therapy. This report discusses a thorough workup for this movement disorder and when to intervene for this distressing condition.

Progressive Spasticity With a Single Magnetic Resonance Imaging Lesion

2021 ◽  
pp. 20-21
Author(s):  
Samantha A. Banks ◽  
Eoin P. Flanagan
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Oligoclonal Bands ◽  
Resonance Imaging ◽  
Fluid Analysis ◽  
Skin Cancers ◽  
Clinical Episode ◽  
History Of ◽  
The Right

A 59-year-old White man with a history of excised basal and squamous cell skin cancers was evaluated for gait difficulties. He had erectile dysfunction but no bowel or bladder dysfunction. He also reported fatigue. He began using a cane for ambulation 2 weeks before evaluation at our facility. His medications included vitamin D and sildenafil. He was a lifelong nonsmoker and had no family history of multiple sclerosis. Neurologic examination at the time of our evaluation 3 years after onset was notable for a positive Hoffman sign on the right and mild weakness of the right triceps but preserved strength elsewhere. He had a spastic gait with moderate spasticity in both lower extremities, hyperreflexic patellar and ankle jerks bilaterally, and bilateral positive Babinski sign. The remainder of the examination was essentially normal. Magnetic resonance imaging of the brain showed a single lesion at the cervicomedullary junction and medullary pyramids, more prominent on the right. There was also some accompanying atrophy that was also visible on cervical spine magnetic resonance imaging. Results of cerebrospinal fluid analysis showed a normal white blood cell count, increased protein concentration (108 mg/dL), and positive oligoclonal bands. The progressive nature of his symptoms, spinal fluid results, and lesion appearance were all consistent with a diagnosis of progressive solitary sclerosis. At the time this patient was seen, no immunomodulatory medications for progressive solitary sclerosis were approved, so no immunomodulatory medication was tried. Ongoing symptomatic management was recommended. Progressive solitary sclerosis is a rare variant of multiple sclerosis in which patients have a single central nervous system demyelinating lesion and development of motor progression attributable to that lesion. Patients can initially have a clinical episode followed by progression or can have a progressive course without an initial relapse.

scholarly journals Mantle Cell Lymphoma Presenting as a Subcutaneous Mass of the Right Leg

2020 ◽  
Vol 13 (2) ◽  
pp. 774-782
Author(s):  
Drew A. Fajardo ◽  
Joel France ◽  
Bogna I. Targonska ◽  
H. Bobby Kahlon ◽  
Max J. Coppes
Keyword(s):  
Bone Marrow ◽  
Mantle Cell Lymphoma ◽  
Cell Lymphoma ◽  
Bone Marrow Involvement ◽  
Non Hodgkin Lymphoma ◽  
Mantle Cell ◽  
History Of ◽  
Subcutaneous Mass ◽  
Systemic Symptoms ◽  
The Right

Mantle cell lymphoma (MCL) is a relatively rare B-cell non-Hodgkin lymphoma, typically presenting with extensive lymphadenopathy, bone marrow involvement, and splenomegaly. Extranodal sites can also be involved. We discuss a 73-year-old man whose MCL presented with a 6-month history of a subdermal mass of the right upper thigh and no systemic symptoms.

scholarly journals The history of cerebrospinal fluid analysis in Brazil

2013 ◽  
Vol 71 (9B) ◽  
pp. 649-652 ◽  
Author(s):  
Jose Antonio Livramento ◽  
Luis dos Ramos Machado
Keyword(s):  
Cerebrospinal Fluid ◽  
20Th Century ◽  
Cerebrospinal Fluid Analysis ◽  
Fluid Analysis ◽  
Strong Point ◽  
History Of

Analysis on cerebrospinal fluid (CSF) in neurological diagnosis has always been considered to be a strong point among the main complementary examinations in Brazil. The present paper reviews the main events in the history of CSF in the neurological sciences, with emphasis on the founders of several CSF schools in our country from the beginning of the 20th century to the present time.

scholarly journals Long term follow-up in a patient with papillary glioneuronal tumor

2004 ◽  
Vol 62 (3b) ◽  
pp. 869-872 ◽  
Author(s):  
Guilherme Borges ◽  
Leonardo Bonilha ◽  
Ana Silvia Menezes ◽  
Luciano de Souza Queiroz ◽  
Edmur Franco Carelli ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Young Female ◽  
Cystic Mass ◽  
Glioneuronal Tumor ◽  
Surgical Specimen ◽  
Papillary Glioneuronal Tumor ◽  
Parietal Lobes ◽  
Long Term Follow Up ◽  
History Of ◽  
The Right

We report a case of a young female patient with a rare and recently described form of brain tumor. This patient had a history of headache, hemiparesis and motor simple partial seizures. Her investigation revealed a brain tumor involving the left frontal and parietal lobes. The radiological images showed a cystic mass with multiple nodular masses and a rim of contrast enhancement extending from the right parietal cortex to the ipsilateral ventricle and corpus callosum. The patient underwent gross resection of the lesion and the histological analysis of the surgical specimen revealed a pseudopapillary structure formed by delicate vessels intermixed with a fibrillary pattern and bordered by intense astrocytic reaction with Rosenthal fibers. These features correspond to the recently described mixed neuronal-glial neoplasm, the papillary glioneuronal tumor. The patient has been followed for five years since the surgical treatment, without evidence of tumor recurrence, confirming the indolent behavior of this type of tumor.

scholarly journals A Young Woman with Ischemic Stroke: Should We Pay More Attention to Varicella Zoster Infection

2016 ◽  
Vol 8 (2) ◽  
pp. 145-150 ◽  
Author(s):  
Cláudia Borbinha ◽  
João Pedro Marto ◽  
Sofia Calado ◽  
Miguel Viana-Baptista
Keyword(s):  
Ischemic Stroke ◽  
Hemorrhagic Transformation ◽  
Vascular Events ◽  
Varicella Zoster ◽  
Fluid Analysis ◽  
History Of ◽  
The Right ◽  
High Index Of Suspicion ◽  
Varicella Zoster Infection

Ischemic and hemorrhagic stroke are recognized complications of Varicella zoster virus (VZV) infections, although uncommon and poorly documented. The authors report the case of a 31-year-old woman admitted with acute ischemic stroke of the right posterior cerebral artery and a history of a thoracic rash 1 month before. Aspirin and simvastatin were prescribed, but the patient suffered a stepwise deterioration the following days, with new areas of infarction on brain imaging. Despite no evidence of cardiac or large vessel embolic sources, anticoagulation was started empirically 6 days after stroke onset. One week later, symptomatic hemorrhagic transformation occurred. The diagnosis of VZV vasculopathy was then considered, and treatment with acyclovir and prednisolone was started with no further vascular events. Cerebrospinal fluid analysis and digital subtraction angiography findings corroborated the diagnosis. The patient was discharged to the rehabilitation center with a modified Rankin scale (mRS) score of 4. On the 6-month follow-up, she presented only a slight disability (mRS score 2). In conclusion, VZV vasculopathy needs to be considered in young adults with stroke. A high index of suspicion and early treatment seem to be important to minimize morbidity and mortality. Anticoagulation should probably be avoided in stroke associated with VZV vasculopathy.

scholarly journals Atypical Presentation of Central Venous Occlusion (CVO) Disease

2019 ◽  
Vol 9 (1) ◽  
pp. 268-270
Author(s):  
Rosnelifaizur R*,Aizat Sabri I, Krishna K,Lenny SS,Azim I, H Harunarashid
Keyword(s):  
Superior Vena ◽  
Vena Cava ◽  
Lymphatic Vessels ◽  
Venous Access ◽  
Venous Occlusion ◽  
Intermittent Fever ◽  
Fluid Analysis ◽  
History Of ◽  
The Right ◽  
End Stage

We reported a case of 58 years old gentleman who known case of end stage renal failure and had history of Right IJC cannulation of venous access on 2012, presented with recurrent shortness of breath, chesty cough and intermittent fever. Otherwise he got no hemoptysis, no recent contact with PTB patients and no joint pain. The same presentation occurred last month with a pleural tapping was done and claimed it was a milky content. No further investigation was done at that moment. This current presentation noted a dullness in percussion up to midzone of right lung and reduce air entry on auscultation as well. The pigtail catheter was inserted over the right pleural space and it was confirmed as a chylothorax with a present of cholesterol in a pleural fluid analysis. Computed tomography of the thorax showed complete occlusion of the superior vena cava with an established collateral circulation. Lymphangiogram revealed lipiodol seen opacified lymph node and lymphatic vessels until the level of T3 on the right and T5 on the left. There was no obvious lipiodol opacification seen at the region of the right thorax. Effusion was improved after the instillation of fibrinolytic agent and the the chest radiograph shows improvement.

scholarly journals Invasive Sino-Orbital Aspergillosis in an Immunocompetent Patient

2019 ◽  
Vol 2 (4) ◽  
pp. 208-211
Author(s):  
OM Okolo ◽  
GM Bot ◽  
IK Onyedibe ◽  
DJ Shilong ◽  
DJ Alfin ◽  
...  
Keyword(s):  
Immunocompetent Patient ◽  
Intracranial Extension ◽  
Cerebrospinal Fluid Analysis ◽  
Fluid Analysis ◽  
Computer Tomography Scan ◽  
History Of ◽  
Antifungal Chemotherapy ◽  
Intracranial Aspergillosis ◽  
The Brain ◽  
Tomography Scan

Invasive aspergillosis that involves intra-orbital and intracranial extension occurs in immunodeficient and immunocompetent patients resulting in significant morbidity and mortality. We report the case of a 38year old farmer who had recurrent fronto-ethmoidal mucocoele and proptosis of the left eye. She presented with a history of hypertension and no other significant findings on examination. Computer tomography scan of the brain showed a left fronto-orbital uniform contrast-enhancing extra-axial lesion with thickened peripheral capsule and an associated left fronto-orbital skull defect. Cerebrospinal fluid analysis did not show any sign of infection. Intra-operative biopsy sample showed cheesy material which on culture grew Aspergillus species that was identified further using molecular methods. Antifungal agents were used to treat the patient. The present case strongly suggests that it is possible to control intracranial aspergillosis with a combination of surgery and antifungal chemotherapy.

scholarly journals Invasive Sino-Orbital Aspergillosis in an Immunocompetent Patient

2019 ◽  
Vol 2 (4) ◽  
pp. 208-211
Author(s):  
OM Okolo ◽  
GM Bot ◽  
IK Onyedibe ◽  
DJ Shilong ◽  
DJ Alfin ◽  
...  
Keyword(s):  
Immunocompetent Patient ◽  
Intracranial Extension ◽  
Cerebrospinal Fluid Analysis ◽  
Fluid Analysis ◽  
Computer Tomography Scan ◽  
History Of ◽  
Antifungal Chemotherapy ◽  
Intracranial Aspergillosis ◽  
The Brain ◽  
Tomography Scan

Invasive aspergillosis that involves intra-orbital and intracranial extension occurs in immunodeficient and immunocompetent patients resulting in significant morbidity and mortality. We report the case of a 38year old farmer who had recurrent fronto-ethmoidal mucocoele and proptosis of the left eye. She presented with a history of hypertension and no other significant findings on examination. Computer tomography scan of the brain showed a left fronto-orbital uniform contrast-enhancing extra-axial lesion with thickened peripheral capsule and an associated left fronto-orbital skull defect. Cerebrospinal fluid analysis did not show any sign of infection. Intra-operative biopsy sample showed cheesy material which on culture grew Aspergillus species that was identified further using molecular methods. Antifungal agents were used to treat the patient. The present case strongly suggests that it is possible to control intracranial aspergillosis with a combination of surgery and antifungal chemotherapy.

Synovial osteochondromatosis in the elbow joint of a Bengal tiger (Panthera tigris tigris)

2001 ◽  
Vol 14 (01) ◽  
pp. 56-59 ◽  
Author(s):  
M. C. Williams ◽  
N. E. Lambrechts
Keyword(s):  
Synovial Membrane ◽  
Elbow Joint ◽  
Joint Fluid ◽  
Panthera Tigris ◽  
Synovial Osteochondromatosis ◽  
Fluid Analysis ◽  
History Of ◽  
Panthera Tigris Tigris ◽  
Bengal Tiger ◽  
The Right

SummaryA 10-year-old Bengal tiger with a history of chronic thoracic limb lameness was presented for clinical evaluation. Radiographs of the elbows revealed extensive osteophyte formation in both joints and three ovoid mineralised densities in the right joint. Joint fluid analysis was consistent with a degenerative joint process. The joints were partially explored arthroscopically. A medial arthrotomy of the right joint allowed collection of synovial membrane samples which, when examined histopathologically, revealed the presence of cartilaginous nodules with central endochondral ossification within the synovial membrane. A diagnosis of synovial osteochondromatosis was made. This case is compared to other cases described in veterinary and human medical literature.Clinical, radiological, and histopathological description of synovial osteochondromatosis in the elbow joint of a Bengal tiger.

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