Inter-leg systolic blood pressure difference predicts cardiovascular events and mortality in incident hemodialysis patients

2019 ◽  
Vol 43 (4) ◽  
pp. 217-224
Author(s):  
Sawako Kato ◽  
Bengt Lindholm ◽  
Abdul Rashid Qureshi ◽  
Hideyuki Mukai ◽  
Yukio Yuzawa ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Relative Risk ◽  
Confidence Interval ◽  
Systolic Blood Pressure ◽  
Pressure Difference ◽  
Cardiovascular Events ◽  
Hemodialysis Patients ◽  
Cumulative Number ◽  
Blood Pressure Difference ◽  
Increased Risk

Background: High inter-arm blood pressure difference, a marker of vascular disease, may be difficult to assess in hemodialysis patients with arm arteriovenous fistulae. We investigated if high inter-leg systolic blood pressure difference associates with cardiovascular events and increased mortality in hemodialysis patients. Methods: Among 118 incident Japanese dialysis patients, bilateral leg blood pressure, arm blood pressure, brachial–ankle pulse wave velocity, and ankle–brachial index were measured, and the relative risk associated with inter-leg systolic blood pressure difference and other indices of vascular status was analyzed. Results: During follow-up (median, 46 months), 18 deaths and 75 cardiovascular events occurred in 38 patients. Kaplan–Meier curves showed that higher inter-leg systolic blood pressure difference was associated with overall (log-rank 9.35, p = 0.002) and cardiovascular (log-rank 5.81, p = 0.02) mortality. The period from the start of dialysis therapy to the first cardiovascular event was shorter as inter-leg systolic blood pressure difference increased (log-rank 23.7, p < 0.0001). In Cox hazard models, inter-leg systolic blood pressure difference greater than median independently predicted deaths (relative risk, 3.8; 95% confidence interval, 1.3–13.9) and cardiovascular events (relative risk, 3.9; 95% confidence interval, 1.9–9.21) after adjustments for age, sex, nutritional status, and diabetes, whereas other indices were not related to the risks. For well-nourished, moderately malnourished, and severely malnourished patients, the cumulative number of cardiovascular events in the high–inter-leg systolic blood pressure difference patients were 4.96, 31.44, and 55.18 events per 100 patient-years. Conclusions: Higher inter-leg systolic blood pressure difference associated with increased risk of mortality and cardiovascular events suggesting that wider application of inter-leg systolic blood pressure difference measurements may be warranted in hemodialysis patients.

INTERARM SYSTOLIC BLOOD PRESSURE DIFFERENCE IS ASSOCIATED WITH A HIGH PREVALENCE OF CARDIO VASCULAR DISEASES- A CROSS-SECTIONAL STUDY IN POLICE WORKER

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Somesh Raju ◽  
Rina Kumari ◽  
Sunita Tiwari ◽  
NS Verma
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Blood Sugar ◽  
Pressure Difference ◽  
Systolic Pressure ◽  
Working Environment ◽  
Vascular Events ◽  
Cross Sectional ◽  
Blood Pressure Difference ◽  
High Prevalence

Background: Interarm systolic blood pressure difference more than 10 mm of Hg is predictor of cardiovascular and metabolic risk. Despite of sufficient physical activity there is high prevalence of obesity in police personal because of stressful working environment. No studies have addressed the significance of interarm pressure difference among them. Therefore, the present study conducted to access the relation of interarm blood pressure difference with obesity in police personnel. Aims and Objective: To estimate the interarm pressure difference in police personal to see its association with their obesity. Material and Method: This cross-sectional observational study done on 245 police workers in PAC, Sitapur, India. Subjects having more than ten years of working experience were included in study. Anthropometric measurements of subject recorded by following standard protocol. Measurement of systolic pressure in both arm recorded simultaneously by mercury sphygmomanometer. Available data analyze and expressed in percentage, mean with SD and chi square test to see the significance of association. Results: According to anthropometric results of subjects 77.14 prcent subjects were having generalised obesity and 82.04 percent of subjects having abdominal obesity. 34.29 percent of subjects showed abnormally high (?10 mmHg) inter-arm systolic blood pressure difference. Both type of obesity showed positive association with blood sugar level but no association with interarm pressure difference. Conclusion: Interarm blood pressure difference is greater in individual having obesity or prolong duration of service. Such subjects are more susceptible to develop coronary artery disease or peripheral arterial disease in future. Early screening can help to detect the vascular events likely to occur in the future Keywords: Body mass index, Waist circumference, Interarm pressure difference, Random blood sugar

Increased Familial Cardiovascular Mortality in Obese Schoolchildren: The Muscatine Ponderosity Family Study

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 262-268
Author(s):  
Trudy L. Burns ◽  
Patricia P. Moll ◽  
Ronald M. Lauer
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Relative Risk ◽  
Confidence Interval ◽  
Relative Weight ◽  
Death Certificates ◽  
Random Group ◽  
Blood Pressure Elevation ◽  
Increased Risk ◽  
Heavy Group

Total and cause-specific mortality was investigated in 387 first- and second-degree deceased adult relatives of three groups of children selected from those who participated in three biennial school surveys in Muscatine, Iowa: the lean group (students in the first quintile of relative weight on all three surveys); the random group (a random sample of all eligible students); and the heavy group (students in the fifth quintile of relative weight on all three surveys). A greater proportion of death certificates for heavy group relatives listed a cardiovascular cause of death (60%) compared with lean (48%) and random (43%) group relatives. The relative risk of dying of cardiovascular disease for heavy group vs random group relatives was 1.41 (95% confidence interval 1.01, 1.98). In a subset of heavy group families identified by children with elevated systolic blood pressure, the proportion of death certificates listing a cardiovascular cause was even higher (76%) and the estimate of relative risk vs random group relatives was 2.20 (95% confidence interval 1.43, 3.37). These results indicate that persistent obesity in children, particularly when accompanied by persistent blood pressure elevation, identifies families whose members are at increased risk of dying of cardiovascular disease.

scholarly journals Association of Interarm Systolic Blood Pressure Difference with Atherosclerosis and Left Ventricular Hypertrophy

PLoS ONE ◽  
2012 ◽  
Vol 7 (8) ◽  
pp. e41173 ◽  
Author(s):  
Ho-Ming Su ◽  
Tsung-Hsien Lin ◽  
Po-Chao Hsu ◽  
Chun-Yuan Chu ◽  
Wen-Hsien Lee ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Hypertrophy ◽  
Systolic Blood Pressure ◽  
Pressure Difference ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Blood Pressure Difference

Interankle systolic blood pressure difference and renal outcomes in patients with chronic kidney disease

Nephrology ◽  
2016 ◽  
Vol 21 (5) ◽  
pp. 379-386 ◽  
Author(s):  
Szu-Chia Chen ◽  
Yi-Chun Tsai ◽  
Jiun-Chi Huang ◽  
Su-Chu Lee ◽  
Jer-Ming Chang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Systolic Blood Pressure ◽  
Pressure Difference ◽  
Renal Outcomes ◽  
Blood Pressure Difference

scholarly journals Arm-ankle systolic blood pressure difference at rest and after exercise in the assessment of aortic coarctation.

Heart ◽  
1995 ◽  
Vol 73 (3) ◽  
pp. 270-276 ◽  
Author(s):  
J. Engvall ◽  
C. Sonnhag ◽  
E. Nylander ◽  
G. Stenport ◽  
E. Karlsson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Pressure Difference ◽  
Aortic Coarctation ◽  
Blood Pressure Difference
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