Ocular complications and loss of vision due to herpes zoster ophthalmicus in patients with HIV infection and a comparison with HIV-negative patients

2013 ◽  
Vol 24 (2) ◽  
pp. 106-109 ◽  
Author(s):  
S Nithyanandam ◽  
M Joseph ◽  
J Stephen

Although the incidence of ocular complications of HIV declined significantly with the wide availability of effective antiretroviral therapy, they are still important and require close collaboration between the HIV physician and the ophthalmologists. This chapter describes the ophthalmic manifestations of HIV infection, tabulated according to the anatomy of the eye. HIV-related conditions and opportunistic infections are described. Particular reference and details are given to important eye infections, such as CMV retinitis, ophthalmic herpes zoster, acute retinal necrosis, and progressive outer retinal necrosis.


2015 ◽  
Vol 21 (3) ◽  
pp. 334-339 ◽  
Author(s):  
Erik Schaftenaar ◽  
Christina Meenken ◽  
G. Seerp Baarsma ◽  
James A. McIntyre ◽  
Georges M. G. M. Verjans ◽  
...  

2013 ◽  
Vol 06 (02) ◽  
pp. 1 ◽  
Author(s):  
Antoine Rousseau ◽  
Tristan Bourcier ◽  
Joseph Colin ◽  
Marc Labetoulle ◽  
◽  
...  

Varicella-zoster virus (VZV) infections are widely distributed in the general population. The lifetime risk of herpes zoster is estimated to be 10–20 %, increasing with age (1–4). Since herpes zoster ophthalmicus (HZO) accounts for 20 % of all locations of shingles, the lifetime risk of HZO is about 1–2 %. The management of ocular complications of VZV infection is now well codified, but sequellae still can occur, despite an armamentarium effective in limiting viral replication and its immune consequences.


2015 ◽  
Vol 42 (12) ◽  
pp. 1207-1208 ◽  
Author(s):  
Shown Tokoro ◽  
Ken Igawa ◽  
Hiroo Yokozeki

Eye ◽  
1994 ◽  
Vol 8 (1) ◽  
pp. 70-74 ◽  
Author(s):  
G W Aylward ◽  
C M P Claoué ◽  
R J Marsh ◽  
N Yasseem

1998 ◽  
Vol 9 (8) ◽  
pp. 476-479 ◽  
Author(s):  
Rich E Umeh

Eight patients, 3 men and 5 women, aged between 24 and 40 years who had herpes zoster ophthalmicus HZO were seen in the Eye Department of the University of Nigeria Teaching Hospital, Enugu between 1994 and 1997. One of the patients was already on treatment for active pulmonary tuberculosis at the time he was first seen. All had skin eruptions at different stages of development in the area of distribution of the first trigeminal nerve on the affected side of the face and head. Ocular examination revealed impaired vision in the affected eye between 6 12 and hand movement in all the patients. All had lid oedema while 5 had ptosis 3 partial and 2 complete . Various degrees of conjunctival injection were observed in all patients while 6 of them had corneal anaesthesia and keratitis. Uveal inflammation, present in all the patients varied from mild iritis in 4 individuals to severe iridocyclitis in the remaining 4. Pupils reacted to light sluggishly in 2 patients while they were dilated and fixed in 3 others. None had any associated abnormalities in the posterior segment. Six of the patients consented and were screened for human immunodeficiency virus HIV infection. Of these, 4, including the patient with pulmonary tuberculosis, tested seropositive while 2 were seronegative. All 8 were treated with topical acyclovir. This was combined with oral acyclovir in one of the patients. Follow up period was between 2 and 52 weeks. During this period skin eruptions and anterior segment signs improved in 5 patients while remaining stable in 3 others; post herpetic neuralgia persisted on the affected side in 4 patients. Patients who were HIV seropositive did not recover as quickly or to the same extent as the seronegative ones. It is concluded that HZO infection may indicate underlying HIV infection in young Africans as has been found in whites.


PEDIATRICS ◽  
1992 ◽  
Vol 89 (4) ◽  
pp. 685-686
Author(s):  
ANTHONY R. CAPUTO ◽  
KEVIN J. MICKEY ◽  
SUQUIN GUO

To the Editor.— The varicella virus is a well known cause of ophthalmologic complications in its classic recurrent form of herpes zoster ophthalmicus. Ocular complications may also accompany the primary infection, however, and have been well documented. These conditions include vesicular lid lesions with corresponding irritation, phlyctenular keratoconjunctivitis, superficial punctate keratitis, uveitis, optic neuritis, and external ophthalmoplegia from encephalitic cranial nerve palsies.1,2 Internal ophthalmoplegia, a rare complication affecting pupillary constriction and accommodation, has also been


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