Group II Phospholipase A2 Content of Tears in Patients with Senile Cataract and Primary Open-Angle Glaucoma

2002 ◽  
Vol 12 (1) ◽  
pp. 40-43 ◽  
Author(s):  
V. V. Aho ◽  
T.J. Nevalainen ◽  
V. Paavilainen ◽  
K.M. Saari
2021 ◽  
Vol 8 (3) ◽  
pp. 24-27
Author(s):  
S.I. Kosuba ◽  
L.P. Novak ◽  
M.V. Skovron

The imaging method in non-penetrating deep sclerectomy (NPDS) was analyzed in 91 patients aged 43 to 89 years with primary open-angle glaucoma. Patients were divided into two groups by age and sex. Group I (n = 46) included the patients who underwent our modified NPDS and group II (n = 45) consisted of patients who were performed the classic NPDS by Fedorov-Kozlov method. After analyzing the data obtained, in group I, staining of juxtacanalicular tissue significantly improved visibility and made it easier to remove compared with group II. The study allows us to conclude about the effectiveness and safety of this visualization technique du­ring surgery.


2017 ◽  
Vol 9 (1) ◽  
pp. 17-23 ◽  
Author(s):  
P Lavaju ◽  
S Shah ◽  
S Sharma ◽  
R Maskey

Background: Diabetes mellitus (DM) is one of the risk factors for Primary open angle glaucoma (POAG). Inclusion of DM as a risk factor for POAG is controversial. The objectives of the study were to investigate whether Type II (T2) DM is a risk factor for POAG and to determine central corneal thickness (CCT) in the subjects with T2DM and to examine the relationship between T2DM and intraocular pressure (IOP).Materials and methods: A comparative cross sectional study was conducted including 189 subjects of age > 40 years. In Group I, 113 patients diagnosed with T2DM and Group II, age and sex matched 76 subjects with POAG without DM was included. Detailed ocular examination, IOP, CCT and funduscopy evaluation was done. Results: Most of the patients were more than 60 years of age with mean age 58 ± 11 years. Male: female ratio was 1:1. POAG was seen in 27.4% of patients with T2DM. Mean IOP in T2DM was 14.67± 2.63mmHg and in non diabetic, 17.25±4.47 mmHg (p <0.00). In group I, mean CCT was 538.83± 22.7μm and in group II, 531.26 ± 20.9μm (p-0.126). There was no association between CCT and glaucoma (p=0.072, 95% CI: -0.76 –17.46). The study could not elicit an association of T2DM with glaucoma. Duration of T2DM did not affect an association between T2DM and glaucoma (p-0.757). Random blood sugar (p<0.001) and oral hypoglycemic drugs (p=0.030) showed an association with glaucoma. Conclusion: The study failed to show an association between T2DM and primary open angle glaucoma and CCT though an association seen with IOP. A larger prospective comparative study may be help in understanding this association. 


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Alper Bilgic ◽  
Aditya Sudhalkar ◽  
Anand Sudhalkar ◽  
Megha Trivedi ◽  
Viraj Vasavada ◽  
...  

Purpose. To compare the outcomes of trabeculectomy using two different routes of bevacizumab administration as an adjunct in patients with primary open angle glaucoma. Methods. Prospective, randomized, masked trial that included 180 eyes of 180 patients of documented primary open angle glaucoma were eligible for surgery. Patients were randomized to receive either a single intraoperative dose of subconjunctival bevacizumab (1.25 mg, Group I) or topical bevacizumab (5 mg/ml) for 30 days (Group II). One eye was randomly selected, if both were eligible for surgery. All patients underwent a complete ocular and systemic examination. Bleb morphology was examined and scored as per Moorfields system (MBGS) at 1, 3, 6, 12, 18, and 24 months postoperatively. Visual field, fundus photography, and disc analysis were performed. Outcome measures (at one year) included (1) comparison of bleb morphology in both groups, (2) proportion of patients achieving surgical success, and (3) side effects of treatment. Results. The groups did not differ with respect to age, sex, and crystalline lens status. Group II patients had significantly lower vascularity scores for central (P=0.042) and peripheral bleb areas (P=0.023) and peripheral nonbleb area (P=0.03). A significantly larger proportion of Group II (n = 88) patients achieved average vascular scores of less than 2.5 (P=0.0056, Fisher’s test) than Group I (n = 85). The groups did not differ in terms of surgical success (96% vs. 94%; P=0.54). No major complications were noted in either group. Conclusion. Topical bevacizumab gives a better vascularity profile at one year, but the studied routes appear equally safe and do not seem to affect the outcome in any other way.


1985 ◽  
Vol 17 (6) ◽  
pp. 341-343 ◽  
Author(s):  
E. Hannappel ◽  
G. Pankow ◽  
F. Grassl ◽  
K. Brand ◽  
G.O.H. Naumann

Author(s):  
E. N. Simakova ◽  
O. V. Stenkova

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.


1990 ◽  
Vol 4 (1) ◽  
pp. 1 ◽  
Author(s):  
In Seop Lee ◽  
Young Suk Yu ◽  
Dong Myung Kim ◽  
Dong Ho Youn ◽  
Jin Q Kim

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