Human amniotic membrane for failed macular hole. A case of initial unsuccessful outcome that resolved after amniotic membrane exchange

2021 ◽  
pp. 112067212110589
Author(s):  
Tomaso Caporossi ◽  
Lorenzo Governatori ◽  
Tommaso Verdina ◽  
Stanislao Rizzo
Keyword(s):  
Visual Acuity ◽  
Macular Hole ◽  
Amniotic Membrane ◽  
Sulfur Hexafluoride ◽  
Silicone Oil ◽  
Human Amniotic Membrane ◽  
Second Surgery ◽  
Myopic Macular Hole ◽  
Oil Injection ◽  
Membrane Patch

Introduction We described a case of initial unsuccessful outcome of failed macular hole treated with amniotic membrane, that resolved after amniotic membrane exchange and silicone oil injection. Case Description a woman affected by a high myopic macular hole that had failed to close after multiple surgeries, had been treated using an amniotic membrane graft and 20% sulfur hexafluoride but, after the gas reabsorption, the macular hole was still open, and the amniotic membrane. A second surgery with a second amniotic membrane patch and silicone oil was carried out. Two weeks after the procedure the macular hole closed, and the final visual acuity improved from 20/400 to 20/100. Conclusions In this case, a second surgery, using a new amniotic membrane graft and a longer-lasting endotamponade, closed the hole and improved the visual acuity.

scholarly journals A Human Amniotic Membrane Plug to Treat Persistent Macular Hole

2020 ◽  
Vol 11 (2) ◽  
pp. 442-447
Author(s):  
Luca Ventre ◽  
Paola Marolo ◽  
Michele Reibaldi
Keyword(s):  
Visual Acuity ◽  
Macular Hole ◽  
Amniotic Membrane ◽  
Functional Results ◽  
Human Amniotic Membrane ◽  
Corrected Visual Acuity ◽  
Macular Holes ◽  
Critical Issues ◽  
Pars Plana

The human amniotic membrane (hAM) has lately demonstrated interesting potential in its retinal applications. Nowadays, the treatment of persistent macular holes is still a challenge. In this paper, we present a case of a hAM plug used to treat a persistent macular hole, with the purpose of highlighting the critical issues of this new surgical procedure. We performed a 23-G pars plana vitrectomy and inserted a hAM plug (diameter of 1.5 mm) under the neuroretinal margins of the hole (diameter of 657 μm). A complete ophthalmic examination with the assessment of best-corrected visual acuity (logMAR units, ETDRS letter score) and optical coherence tomography (OCT) scans were collected at 1, 4, 6, and 10 weeks after surgery. Visual acuity changed from logMAR 1.0 (1) preoperatively to logMAR 1.0 (2), 1.0 (4), 0.9 (9), and 0.9 (10) at 1, 4, 6, and 10 weeks of follow-up, respectively. The 1 week postoperative OCT did not show neuroretinal adhesion over the plug, but the following visits showed reattachment of the margins with partial neuroretinal ingrowth. These findings suggest that the correct adaptation of the size of the hAM plug to the macular hole is essential to allow the anatomical closure of the hole and potential functional results.

Amniotic membrane for retinal detachment due to paravascular retinal breaks over patchy chorioretinal atrophy in pathologic myopia

2019 ◽  
Vol 30 (2) ◽  
pp. 392-395 ◽  
Author(s):  
Tomaso Caporossi ◽  
Lorenzo De Angelis ◽  
Bianca Pacini ◽  
Stanislao Rizzo
Keyword(s):  
Optical Coherence Tomography ◽  
Amniotic Membrane ◽  
Silicone Oil ◽  
Internal Limiting Membrane ◽  
Pathologic Myopia ◽  
Human Amniotic Membrane ◽  
Optical Coherence ◽  
Chorioretinal Atrophy ◽  
Retinal Breaks ◽  
Membrane Patch

Purpose: To describe a new surgical technique, using a human amniotic membrane patch, in two cases of retinal detachment with paravascular retinal breaks over patchy chorioretinal atrophy in pathologic myopia, already underwent pars plana vitrectomy with the internal limiting membrane peeling for myopic foveoschisis. Methods: Surgical technique description with surgical video. A 23-gauge pars plana vitrectomy was performed. A human amniotic membrane patch was implanted under the neuroretina to seal the posterior retinal break. Standard silicone oil tamponade was performed at the end of the surgery. The patients were positioned face down after the operation for the first week. Optical coherence tomography scans were used in the follow-ups. Results: The 2 weeks postoperative optical coherence tomography showed a new tissue growth over the human amniotic membrane patch. The 3 months optical coherence tomography showed the new tissue entirely covering the human amniotic membrane plug. Visual acuity improved from 20/2000 (2 LogMAR) to 20/250 (1.1 LogMAR) 3 months after the operation in both patients. The silicone oil was extracted 2 months after surgery, and no recurrences were observed. The patient’s visual acuity remained stable at 20/250 after the silicone oil extraction. Conclusion: In these complex cases, human amniotic membrane transplantation can be a valid option, when internal limiting membrane has already been peeled in previous surgeries, to seal the posterior retinal breaks over high myopic chorioretinal atrophy, with encouraging results.

A human Amniotic Membrane plug to manage high myopic macular hole associated with retinal detachment

2019 ◽  
Vol 98 (2) ◽  
Author(s):  
Tomaso Caporossi ◽  
Lorenzo Angelis ◽  
Bianca Pacini ◽  
Ruggero Tartaro ◽  
Lucia Finocchio ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Macular Hole ◽  
Amniotic Membrane ◽  
Human Amniotic Membrane ◽  
Myopic Macular Hole

Risk Factors For Recurrent Myopic Macular Hole Retinal Detachment After Silicone Oil Removal In Patients With Open Flat Macular Hole

2021 ◽  
Author(s):  
Hamouda Hamdy Ghoraba ◽  
Hosam Othman Mansour ◽  
Mohamed Ahmed Abdelhafez Elsayed ◽  
Adel Galal Zaky ◽  
Mohamed Amin Heikal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Retinal Detachment ◽  
Macular Hole ◽  
Silicone Oil ◽  
Significant Risk ◽  
Minimum Diameter ◽  
Univariate Logistic Regression Analysis ◽  
Macular Hole Retinal Detachment ◽  
Myopic Macular Hole ◽  
Group 2

Purpose: To evaluate the risks that might be associated with recurrent macular hole retinal detachment (Re MHRD) after silicone oil (S.O) removal in myopic patients with open flat macular hole (MH). Methods: In this retrospective series, we assessed the different factors that might be associated with recurrent MHRD after S.O removal in 48 eyes with open flat MH that underwent S.O removal after successful MHRD repair by dividing the enrolled eyes into 2 groups: group 1 included 38 eyes with flat open MH and flat retina after S.O removal and group 2 included 10 eyes with flat open MH and recurrent MHRD after S.O removal. Results: Ten of 48 eyes (20.8%) with open flat MH developed recurrent MHRD after S.O removal. Univariate logistic regression analysis revealed that MH at the apex of PS, MH minimum diameter, hole form factor (HFF) and MH index (MHI) were significant risk factors for recurrent MHRD after S.O removal in myopic patients with open flat MH. Conclusions: If there is a "flat open" MH that is large, located at the apex of PS or with HHF or MHI of less than 0.9-0.5, it has a high chance of recurrent MHRD after S.O removal.

scholarly journals A New Sutureless Illuminated Macular Buckle Designed for Myopic Macular Hole Retinal Detachment

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Ahmed M. Bedda ◽  
Ahmed M. Abdel Hadi ◽  
Mohamed Lolah ◽  
Muhammad S. Abd Al Shafy
Keyword(s):  
Visual Acuity ◽  
Retinal Detachment ◽  
Macular Hole ◽  
High Myopia ◽  
Terminal Part ◽  
Macular Hole Retinal Detachment ◽  
Myopic Macular Hole ◽  
The Mean ◽  
Visual Results

Purpose. To report the anatomic and visual results of a new sutureless illuminated macular buckle designed for patients with macular hole retinal detachment related to high myopia (MMHRD). Design. Prospective nonrandomized comparative interventional trial. Methods. Twenty myopic eyes of 20 patients (mean age, 51.4 years; range, 35–65 years) presenting with MMHRD with a posterior staphyloma, in whom the new buckle was used, were evaluated. The buckle used was assembled from a 5 mm wide sponge and a 7 mm wide silicone tire; it was fixed utilizing the sterile topical adhesive Histoacryl Blue (B Braun, TS1050044FP) which polymerizes in seconds upon being exposed to water-containing substances. The primary outcomes measured included aided visual acuity (BCVA) and optical coherence tomography (OCT) findings. The mean follow-up period was 6 months. Results. Postoperatively, the MH closure was identified by OCT in 8 (40%) eyes. The mean BCVA increased from 0.11 to 0.21 (p<0.005). The axial length of the eyes included decreased from 30.5 mm preoperatively to 29.8 mm (p=0.002) postoperatively. Conclusion. Preparation of the new sutureless macular buckle is simple and easy. Illumination of the terminal part of the buckle ensures proper placement. Histoacryl Blue is effective in fixing the buckle in its place for at least 6 months with no reported intra- or postoperative complications.

scholarly journals Novel method of plugging the hole: Anatomical and functional outcomes of human amniotic membrane-assisted macular hole surgery

2020 ◽  
Vol 32 (4) ◽  
pp. 361
Author(s):  
Ramesh Venkatesh ◽  
NareshKumar Yadav ◽  
Sherina Thomas ◽  
Arpitha Pereira ◽  
KBhujang Shetty
Keyword(s):  
Macular Hole ◽  
Amniotic Membrane ◽  
Functional Outcomes ◽  
Human Amniotic Membrane ◽  
Macular Hole Surgery ◽  
Novel Method

scholarly journals A Female Case of X-Linked Retinoschisis with Macular Hole Bilaterally

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
A. Altun
Keyword(s):  
Visual Acuity ◽  
Macular Hole ◽  
Pars Plana Vitrectomy ◽  
Silicone Oil ◽  
Surgical Experience ◽  
Flap Technique ◽  
Macular Holes ◽  
Female Case ◽  
Pars Plana

Purpose. We aimed at reminding that X-linked retinoschisis may also be seen in female patients and share our vitreoretinal surgical experience. Methods. The patient underwent pars plana vitrectomy including the closure of the macular holes with inverted ILM flap technique bilaterally. Lens extractions were performed by phacoemulsification during the removal of silicone oil endotamponade. Patient. An 18-year-old girl with X-linked retinoschisis and large macular holes in both eyes presented to the clinic of ophthalmology. It was confirmed that the patient had RS1 mutation Results. Nine-month-follow-up was uneventful for retinal findings. Significant improvement in visual acuity was achieved, and macular holes were remained closed. Conclusion. In cases with large macular holes due to XLR, an inverted ILM flap technique might be safe and effective. Four-month-silicone-endotamponade might be sufficient.

Human amniotic membrane patch and platelet-rich plasma to promote retinal hole repair in a recurrent retinal detachment

2020 ◽  
pp. 112067212095331
Author(s):  
Federico Di Tizio ◽  
Irene Gattazzo ◽  
Federico Di Staso ◽  
Mariachiara Di Pippo ◽  
Fabio Guglielmelli ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Surgical Technique ◽  
Amniotic Membrane ◽  
Silicone Oil ◽  
Platelet Rich Plasma ◽  
High Viscosity ◽  
Pathologic Myopia ◽  
Human Amniotic Membrane ◽  
Silicon Oil ◽  
Retinal Hole

Purpose: To present a modified surgical technique, based on a combination of human amniotic membrane (hAM) patch and autologous Platelet-rich plasma (PRP) in a case of recurrent retinal detachment (RRD) due to a perivascular retinal hole over an area of staphyloma in an eye with pathologic myopia. Methods: Presenting the surgical technique with the disposal of surgical video. After performing 23-gauge pars plana vitrectomy (PPV) the hAM patch was inserted under the neuroretina through the perivascular hole and PRP was injected on top to speed up the closure of the hole. To complete the surgical procedure High Viscosity Silicon oil (5000cst) was used as tamponade. The patient was prescribed to maintain a face-down position for the first 3 days after the operation. Follow-up was evaluated through Optical coherence tomography (OCT) scans. Results: The 3 days postoperative OCT showed a flat retina with the filling of the myopic staphyloma. The hAM patch was well positioned and the retinal hole could not be identified. At 6 weeks from intervention, the site of the retinal hole at OCT scan was covered by new tissue. Silicone oil was removed 3 months later with no recurrence. Conclusion: hAM transplantation is a novel technique in case of retinal detachment recurrences to seal retinal holes over high myopic chorioretinal atrophy. The adjunctive use of PRP and high viscosity silicon oil allows to reducing the standard face-down positioning timing, representing a valid solution for elderly patients who have difficulties maintaining the position for long periods.

scholarly journals Silicone Oil Reinjection without Macular Buckling for Treatment of Recurrent Myopic Macular Hole Retinal Detachment after Silicone Oil Removal

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Hammouda Hamdy Ghoraba ◽  
Sameh Mohamed Elgouhary ◽  
Hosam Osman Mansour
Keyword(s):  
Retinal Detachment ◽  
Macular Hole ◽  
Silicone Oil ◽  
Case Series ◽  
Oil Removal ◽  
Interventional Study ◽  
Silicone Oil Removal ◽  
Macular Hole Retinal Detachment ◽  
Medical Reports ◽  
Myopic Macular Hole

Purpose. To evaluate the efficacy of silicone oil (S.O) reinjection without macular buckling for treatment of recurrent myopic macular hole retinal detachment (MHRD) after silicone oil removal.Methods. A retrospective consecutive interventional study from medical reports on cases of myopic MHRD. Fifty-three eyes of 51 patients underwent silicone oil removal after successful repair of MHRD were reviewed. The main outcomes were the retinal status after silicone oil removal and management of recurrent cases.Results. The rate of recurrent RD (Re RD) after silicone oil removal was 11.3% (6 out of 53 eyes). One case refused any other interference. In the remaining 5 eyes, 4 eyes (80%) could be reattached by S.O re-injection and one eye (20%) developed Re RD after S.O re-injection. Range of followup after management of recurrence was 5–53 months (mean 18.7 months).Conclusions. This case series concluded that the risk factors for recurrent RD after silicone oil removal from cases of myopic MHRD were high myopia, open flat MH, and large posterior staphyloma. Revision of vitrectomy and S.O re-injection can reattach most of recurrent cases.

scholarly journals Endophthalmitis and Retinal Detachment after Ocular Injury by Animal Inoculation Needle

2021 ◽  
Vol 62 (9) ◽  
pp. 1305-1308
Author(s):  
Leeha Kwon ◽  
Yong-Wun Cho ◽  
Seong-Wook Seo ◽  
Seong-Jae Kim ◽  
In Young Chung ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Retinal Detachment ◽  
Silicone Oil ◽  
Ocular Injury ◽  
Early Vitrectomy ◽  
Corrected Visual Acuity ◽  
Vitreous Prolapse ◽  
Oil Injection ◽  
Best Corrected Visual Acuity

Purpose: To report a case of endophthalmitis and retinal detachment after injury caused by an animal inoculation needle. Case summary: A 39-year-old man received an injury to his left eye with an animal inoculation needle while vaccinating a pig came to the hospital due to decreased visual acuity. At initial presentation, the best-corrected visual acuity in the left eye was “counting fingers,” and slit lamp examination revealed corneal lacerations, anterior capsule rupture, and traumatic cataract. Ultrasonography showed no specific findings in the vitreous and retina. Primary corneal suture, phacoemulsification, anterior vitrectomy due to rupture of the posterior capsule and vitreous prolapse, intraocular lens implantation, and intravitreal antibiotic injection were performed. On day 1 postoperatively, vitrectomy, anterior chamber irrigation, intravitreal antibiotic injection, and silicone oil injection were performed as signs of endophthalmitis, such as hypopyon and retinal tear, and focal retinal detachment were observed during surgery. Silicone oil removal was performed 7 months after the operation and the best-corrected visual acuity was 0.6. There has been no recurrence during follow-up. Conclusions: This is the first report in Korea of ocular injury caused by an animal inoculation needle. If the fundus is not observed in such injuries, there is a possibility of endophthalmitis and retinal detachment and early vitrectomy should be considered.

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