scholarly journals Influence of a Structured Exercise Training on Patients Reported Quality of Life in Colorectal Cancer Patients After Adjuvant Chemotherapy: A Pilot Study

2020 ◽  
Vol 19 ◽  
pp. 153473542093845 ◽  
Author(s):  
Gudrun Piringer ◽  
Bernhard Holzner ◽  
Beate Mayrbaeurl ◽  
Sonja Heibl ◽  
Monika Sztankay ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Adjuvant Chemotherapy ◽  
Exercise Training ◽  
Emotional Functioning ◽  
Treatment Strategies ◽  
Patient Reported ◽  
Global Quality Of Life ◽  
Colorectal Cancer Patients

Purpose: Cancer and its treatment strategies can have adverse effects on physical functioning and quality of life. Treatment strategies for better quality of life are still an unresolved issue. Physical activity is a promising treatment strategy that still has to be fully investigated. Methods: The ABCSG C07-EXERCISE study evaluated the feasibility of a 1-year exercise training after adjuvant chemotherapy in colorectal cancer patients. The present report presents the patient-reported outcomes during the exercise training. Fourteen patients of one center filled out the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ C30) questionnaire at 5 time points after initiating a 1-year exercise training. Results: At baseline, patients scored social functioning, emotional functioning, financial impact, insomnia, and diarrhea much worse than the German general population. After 1 year of a structured exercise training, a large improvement was reported for social functioning; moderate improvements were reported for pain, diarrhea, financial impact, and taste; and a small change for physical and emotional functioning as well as for global quality of life. Conclusions: The present study observed improvements of social, physical, and emotional functioning as well as global quality of life after 1 year of a structured exercise training in patients with locally advanced colorectal cancer after receiving adjuvant chemotherapy. To enhance compliance, sufficient support and different sport facilities should be offered. The positive effect of exercise on patient-reported outcomes, disease-free survival, and overall survival in cancer survivors have to be further investigated in further randomized clinical trials.

scholarly journals The Quality of Life of Patients with Hereditary Nonpolyposis Colorectal Cancer Undergoing Preoperative Chemoradiation

2020 ◽  
Vol 10 (18) ◽  
pp. 6585
Author(s):  
Valeriu Aurelian Chirica ◽  
Mioara Matei ◽  
Roxana Postolica ◽  
Liliana Chelaru ◽  
Irina Mihaela Esanu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Genetic Risk ◽  
Emotional Functioning ◽  
Preoperative Chemoradiation ◽  
Symptom Scale ◽  
Cross Sectional ◽  
Questionnaire Version ◽  
Colorectal Cancer Patients

Of all the neoplastic sites, colorectal cancer (CRC) is one of the most common cancers in the family. Studies estimate that approximately 30% of all the CRC cases are a hereditary form of the disease with a potentially high impact on the quality of life (QoL), with a high risk of recurrence, and with bio–psycho–social functioning. The aim of the study was to assess the QoL of colorectal cancer patients with genetic risk by using the European Organisation for Research and Treatment of Cancer (EORTC) questionnaire version QLQ-CR29. Materials and methods: The cross-sectional, single-center study was performed on a group of 32 patients with genetic risk of colorectal cancer, who underwent preoperative chemoradiation and surgery. Results: The series of values for the scores on the symptom scale varied between 15 and 30, and the average level of symptom scores did not differ significantly between gender (22.0 vs. 22.75; p = 0.636), highlighting a moderate impairment of QoL. Scores for the emotional functioning scale were significantly lower in men (10.33 vs. 13.25; p = 0.049), as were the scores for the physical functions (15.67 vs. 19.15; p = 0.039), showing a decrease in QoL. Conclusions: The overall score showed an average QoL in patients with colorectal cancer with genetic risk, highlighting significant differences in psycho-emotional functioning between women and men.

scholarly journals Long-term neuropathy and quality of life in colorectal cancer patients treated with oxaliplatin containing adjuvant chemotherapy

2019 ◽  
Vol 58 (4) ◽  
pp. 398-406 ◽  
Author(s):  
L. M. Soveri ◽  
A. Lamminmäki ◽  
U. A. Hänninen ◽  
M. Karhunen ◽  
P. Bono ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Adjuvant Chemotherapy ◽  
Cancer Patients ◽  
Colorectal Cancer Patients

scholarly journals Patient-Reported Outcomes of Colorectal Cancer Patients in University Malaya Medical Centre

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 102s-102s
Author(s):  
B.A. Magaji ◽  
F.M. Moy ◽  
C.W. Law ◽  
A.C. Roslani
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients ◽  
Malaysian Chinese

Background: In Malaysia, colorectal cancer is ranked the second most frequent cancer among men and women. Despite that, research on patient-reported outcomes in colorectal cancer is scarce. Aim: This study aimed to determine the pattern and factors affecting health-related quality of life (HRQOL) among colorectal cancer patients treated at the University Malaya Medical Centre (UMMC), Malaysia. Methods: This study is a cross sectional assessment of health-related quality of life of colorectal cancer patients attending UMMC using locally validated Bahasa Malaysia (BM) and Malaysian Chinese versions of the EORTC QLQ-C30 core and colorectal cancer specific EORTC-QLQ-CR29 tools. Data were drawn from patients' records, national registration department and interviews (physical and telephone). Statistical analyses included descriptive, psychometric evaluations and stepwise multiple linear regression models. Results: The reliability and validity of the BM and Malaysian Chinese tools were examined among 189 patients. The questionnaires were acceptable to the patients, with adequate Cronbach's alpha in all but the cognitive function scale, test-retest coefficient were adequate, and all items fulfilled the criteria for convergent and discriminant validity except question number 5 in QLQ-C30 in both the tools. Three hundred and twenty patients not involved in the validation study were surveyed and these patients rated their global health status/quality of life (GHS/QOL) and functional well-being higher than the EORTC reference values and reported fewer symptoms. Ethnicity was associated with the GHS/QOL at univariate level only. Role, social/family functioning scales were the two independent predictors of GHS/QOL and both are modifiable. Conclusion: Proactive engagement of patients to share their experiences with colorectal cancer and its treatment is recommended. Emphasis should be role, social and family functions, which were found to be proxies for the overall GHS/QOL.

Safety and Quality of Life in the Treatment of Non-metastasic Colorectal Cancer Patients: 5-fluorouracil Versus Capecitabine

2019 ◽  
Author(s):  
Julia Sánchez-Gundín ◽  
Cristina Martín-Sabroso ◽  
Ana M. Fernández-Carballido ◽  
D. Barreda-Hernández ◽  
Ana I. Torres-Suárez
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Colorectal Cancer Patients

scholarly journals Psychometric validation of the Moroccan version of the EORTC QLQ-C30 in colorectal Cancer patients: cross-sectional study and systematic literature review

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yacir El Alami ◽  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Saber Boutayeb ◽  
Said Benamr ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Discriminant Validity ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Background Health-related quality of life is mainly impacted by colorectal cancer which justified the major importance addressed to the development and validation of assessment questionnaires. We aimed to assess the validity and reliability of the Moroccan Arabic Dialectal version of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (QLQ-C30) in patients with colorectal cancer. Methods We conducted a cross-sectional study using the Moroccan version of the EORTC QLQ-C30 on colorectal cancer patients from the National Oncology Institute of Rabat, in the period from February 2015 to June 2017. The QLQ-C30 was administered to 120 patients. Statistical analysis included reliability, convergent, and discriminant validity as well as known-groups comparisons. Results In total, 120 patients with colorectal cancer were included in the study with 38 (32%) patients diagnosed with colon cancers. Eighty-two patients (68%) had rectal cancer, among which 29 (24%) patients with a stoma. The mean age of diagnosis was 54 years (+/− 13.3). The reliability and validity of the Arabic dialectal Moroccan version of the EORTC QLQ-C30 were satisfactory. [Cronbach’s alpha (α =0.74)]. All items accomplished the criteria for convergent and discriminant validity except for question number 5, which did not complete the minimum required correlation with its own scale (physical functioning). Patients with rectal cancer presented with bad Global health status and quality of life (GHS/QOL), emotional functioning as well as higher fatigue symptoms compared to patients with colon cancer. The difference between patients with and without stoma was significant for diarrhea and financial difficulty. Conclusions The Moroccan Arabic Dialectal version of the QLQ-C30 is a valid and reliable measure of health-related quality of life (HRQOL) in patients with colorectal cancer.

Are gender-associated differences in quality of life in colorectal cancer patients disease-specific?

2009 ◽  
Vol 18 (5) ◽  
pp. 547-555 ◽  
Author(s):  
Johannes Giesinger ◽  
Georg Kemmler ◽  
Verena Mueller ◽  
August Zabernigg ◽  
Beate Mayrbaeurl ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Colorectal Cancer Patients ◽  
Disease Specific
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