scholarly journals Anticholinergic Burden and Dry Mouth in Middle-Aged People

2019 ◽  
Vol 5 (1) ◽  
pp. 62-70
Author(s):  
A. Tiisanoja ◽  
A.-M.H. Syrjälä ◽  
A. Kullaa ◽  
P. Ylöstalo
Keyword(s):  
Regression Models ◽  
Antihypertensive Drugs ◽  
Salivary Flow ◽  
Dry Mouth ◽  
Subjective Feeling ◽  
Oral Diseases ◽  
Middle Aged ◽  
Aged People ◽  
Prophylactic Measures ◽  
Anticholinergic Burden

Introduction:Anticholinergic burden refers to the cumulative effect of taking 1 or more drugs with anticholinergic properties. At the moment, little is known about the association between the anticholinergic burden and dry mouth.Objectives:The objective of this article was to study, whether an anticholinergic burden is associated with dry mouth among middle-aged people.Methods:The study population included 1,345 people aged 46 y from the Northern Finland Birth Cohort 1966 (NFBC1966) study, who took part in a clinical medical and dental examination during 2012–2013. Medication data comprised both self-reported drug use and information obtained from the national register. Anticholinergic burden was measured using 10 different anticholinergic scales. Dry mouth was defined on the basis of having either a subjective feeling of dry mouth (xerostomia) or objectively measured low unstimulated or stimulated whole salivary flow rates (hyposalivation). Poisson regression models with robust error variance were used to estimate relative risk (RR). Regression models were adjusted for sex, smoking, diabetes, rheumatoid diseases, depressive symptoms, anxiety, total number of drugs, and antihypertensive drugs.Results:Approximately 14% of the participants reported having xerostomia and about 2% had hyposalivation. The RRs of different anticholinergic scales for xerostomia varied from 1.05 to 1.68. The scales’ RRs were between 0.89 and 2.03 for low unstimulated whole salivary flow (<0.1 mL/min) and between 0.59 and 1.80 for low stimulated whole salivary flow (<0.7 mL/min). Seven of 10 studied anticholinergic scales associated statistically significantly with dry mouth, either with xerostomia or hyposalivation.Conclusion:Most of the anticholinergic scales were associated with dry mouth, either with xerostomia or hyposalivation. There was considerable variation in the strength of the associations between anticholinergic scales and dry mouth.Knowledge Transfer Statement:The findings of this study suggest that dentists should take notice of the use of drugs with anticholinergic properties and their harmful effects among middle-aged people. Dentists should provide these patients with necessary guidance on how to cope with dry mouth and give them prophylactic measures against oral diseases associated with dry mouth.

Complex treatment of periodontitis: patient’s reaction to the therapy

2020 ◽  
Vol 25 (2) ◽  
pp. 97-100
Author(s):  
A. K. Iordanishvili ◽  
V. A. Guk ◽  
A. A. Golovko
Keyword(s):  
Elderly People ◽  
Periodontal Diseases ◽  
Personal Characteristics ◽  
The Elderly ◽  
Comprehensive Treatment ◽  
Complex Treatment ◽  
Middle Aged ◽  
Aged People ◽  
Dental Rehabilitation ◽  
Success Of Treatment

Relevance. The success of treatment of periodontal diseases directly depends on the patient’s response to the therapy, therefore, the characteristics of the person’s personal characteristics can affect both the effectiveness of treatment and the prevention of relapse of the disease.Purpose. To study the features of the internal picture of the disease in the process of complex treatment of adult patients suffering from chronic generalized periodontitis.Materials and methods. The generally accepted comprehensive treatment of chronic generalized periodontitis in 69 middle-aged and elderly men was carried out taking into account the personal response of patients Solovyov «Psychosensory-anatomical-functional maladaptation syndrome».Results. When patients were discharged from the hospital, there was a difference in the phenomena of maladaptation among the elderly and middle-aged: in middle-aged people, sufficient adaptation to the conditions of existence was determined; in elderly people, due to the existing comorbid pathology, a state of maladaptation was diagnosed, which was caused by the presence of complaints of defects in the dentition.Conclusion. In elderly people, as soon as possible after completion of treatment in a hospital, dental rehabilitation cannot be considered completed, which requires the adoption of organizational measures for their timely provision of dentures.

scholarly journals Spatio-temporal evolution and influencing mechanism of the COVID-19 epidemic in Shandong province, China

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jinlong Shi ◽  
Xing Gao ◽  
Shuyan Xue ◽  
Fengqing Li ◽  
Qifan Nie ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Temporal Evolution ◽  
Geographical Location ◽  
Shandong Province ◽  
Control Measures ◽  
Middle Aged ◽  
Health Crisis ◽  
Aged People ◽  
Spatio Temporal ◽  
And Control

AbstractThe novel coronavirus pneumonia (COVID-19) outbreak that emerged in late 2019 has posed a severe threat to human health and social and economic development, and thus has become a major public health crisis affecting the world. The spread of COVID-19 in population and regions is a typical geographical process, which is worth discussing from the geographical perspective. This paper focuses on Shandong province, which has a high incidence, though the first Chinese confirmed case was reported from Hubei province. Based on the data of reported confirmed cases and the detailed information of cases collected manually, we used text analysis, mathematical statistics and spatial analysis to reveal the demographic characteristics of confirmed cases and the spatio-temporal evolution process of the epidemic, and to explore the comprehensive mechanism of epidemic evolution and prevention and control. The results show that: (1) the incidence rate of COVID-19 in Shandong is 0.76/100,000. The majority of confirmed cases are old and middle-aged people who are infected by the intra-province diffusion, followed by young and middle-aged people who are infected outside the province. (2) Up to February 5, the number of daily confirmed cases shows a trend of “rapid increase before slowing down”, among which, the changes of age and gender are closely related to population migration, epidemic characteristics and intervention measures. (3) Affected by the regional economy and population, the spatial distribution of the confirmed cases is obviously unbalanced, with the cluster pattern of “high–low” and “low–high”. (4) The evolution of the migration pattern, affected by the geographical location of Wuhan and Chinese traditional culture, is dominated by “cross-provincial” and “intra-provincial” direct flow, and generally shows the trend of “southwest → northeast”. Finally, combined with the targeted countermeasures of “source-flow-sink”, the comprehensive mechanism of COVID-19 epidemic evolution and prevention and control in Shandong is revealed. External and internal prevention and control measures are also figured out.

scholarly journals Effect of a newly developed pastille on the salivary flow rate in subjects with dry mouth symptoms: a randomized, controlled, monocentric clinical study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
S. Bielfeldt ◽  
D. Wilhelm ◽  
C. Neumeister ◽  
U. Schwantes ◽  
K. -P. Wilhelm
Keyword(s):  
Surface Tension ◽  
Flow Rate ◽  
Gum Arabic ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Dry Mouth ◽  
Main Ingredient ◽  
Control Product ◽  
Swallowing Problems ◽  
The Mean

Abstract Background Xerostomia is associated with several diseases and is a side effect of certain drugs, resulting from reduced saliva secretion. Often, aged and sometimes younger people suffer from (idiopathic) xerostomia. Chewing gum and sucking pastilles may relieve symptoms of xerostomia by increasing the salivary flow rate due to the mechanical effect of sucking and gustatory stimulation. Swallowing problems and the urge to cough or experiencing a tickling sensation in the throat might be alleviated through a reduction in dry mouth symptoms. We investigated whether a pastille containing four polysaccharides increased the salivary flow rate and relieved the symptoms of dry mouth. Methods Participating subjects with xerostomia were randomized into two equally balanced treatment groups. Subjects received the pastille on Day 1 and a control product (Parafilm®) on Day 3, or vice versa. Unstimulated saliva was collected every 2.5 min for 0–10 min. Stimulated saliva was collected after subjects sucked the pastille or the control product. The salivary flow rate was determined gravimetrically, and, in parallel, the feeling of dry mouth was assessed using a visual analog scale. Saliva surface tension was measured in pooled saliva samples (0–5 min of sampling). Additionally, in stimulated saliva from six subjects who sucked the pastille, the presence of the main ingredient—gum arabic—was examined by Raman spectroscopy. Results Chewing the pastille significantly increased the mean salivary flow rate by 8.03 g/10 min compared to the mean changes after chewing the control product (+ 3.71 g/10 min; p < 0.0001). The mean score of dry mouth was significantly alleviated by the pastille (− 19.9 ± 17.9 mm) compared to the control product (− 3.3 ± 18.1 mm). No difference between the two products was seen regarding the saliva surface tension. Gum arabic was present in the saliva of all investigated subjects for up to 10 min after sucking the pastille. Conclusions The pastille was well tolerated and effective in increasing the salivary flow rate and reducing mouth dryness after sucking. These results were in line with the detection of the main ingredient, gum arabic, in saliva for up to 10 min after sucking the pastille. Trial registration German Register Clinical Trials (Deutsches Register Klinische Studien, DRKS) DRKS-ID: DRKS00017393, Registered 29 May 2019, https://www.drks.de/drks_web/navigate.do?navigationId=trial. HTML&TRIAL_ID = DRKS00017393.

信仰與斷裂——山中村祭祀圈的變遷與村民的奉祀理解

2021 ◽  
Vol 19 (1) ◽  
pp. 083-114
Author(s):  
楊國柱 楊國柱 ◽  
吳金奇 Yang, Kuo-Chu
Keyword(s):  
Local Community ◽  
Health And Safety ◽  
Belief System ◽  
The Elderly ◽  
Middle Aged ◽  
Aged People ◽  
Mountain Village ◽  
Field Investigations ◽  
Meaning Interpretation ◽  
The Village

<p>嘉義縣民雄鄉山中村1（舊稱牛斗山或牛稠山），因牛稠溪域流經村莊而得此名，早期是全鄉人口最大村。山中村宗教信仰普遍為民間信仰，村莊主廟為廣濟宮，以奉祀池府王爺、媽祖、鄭成功為主，但村莊發展及信仰主體係圍繞池府王爺。本文採用文獻分析、田野調查及立意取樣後進行深度訪談，以探討山中村祭祀圈之形成，以及村民如何理解不同神靈之內涵，進而有助於山中村之社區發展與文化資源保存。</p> <p>藉由祭祀圈概念切入，以理解山中村社區各神靈祭祀圈的範圍與分布，進而探討地方社區信仰中心發展，與山中村民對不同神靈認知及意義之解讀。經研究發現：（一）隨著人口增加及集居地擴大，主廟的祭祀圈變大；由於廟務活動增加，牛斗山土地公廟的祭祀圈擴大；五營中的東、西兩營，未隨著社區的新增而往外遷移，因此祭祀圈無明顯變化。（二）山中村神靈祭祀圈的分布，「五營」與居民輪祀居住的地理範圍有關，原具有分群概念的輪祀傳統逐漸模糊：老者對此模糊；中年人認知些許；青年則不明白為何奉祀，宗教信仰傳承出現斷層的可能。（三）山中村民對不同祭祀圈神靈解讀有所異同，普遍難闡述神靈的由來及背景，較理解者屬老年人；其次為中年人；青年人則對神靈認知不清楚。（四）不同祭祀圈神靈意義與山中村民早期生活環境較有其關聯性，老年人多數提及身體健康及平安；中年人求財運、事業；青年人求課業順利。據此，就結論提出建議以供參考。</p> <p>&nbsp;</p><p>Shanzhong Village (formerly known as Niudou Mountain or Niuhou Mountain) in Minxiong Township, Chiayi County, got its name because the Niuhou Stream passed through the village. In the early days, it was the village with the largest population in the township. For the Guangji Palace, it is mainly dedicated to the worship of Lord Chifu, Mazu and Zheng Chenggong (Cheng Ch&rsquo;eng-Kung), but the village development and belief system surrounds Lord Chifu. This paper uses literature analysis, field investigations, and intentional sampling to conduct in-depth interviews to discuss the formation of the mountain village sacrificial circle and how the villagers understand the connotation of different gods, which can help the community development and cultural resource preservation of the mountain village. </p> <p> Through research, the concept of the religious field was cut in to understand the scope and distribution of the religious fields of the various deities in the Shanzhong Village community, and to discuss the development of local community faith centers and the understanding and meaning interpretation of the different deities of the Shanzhong villagers. The research found: (1) The religious realms become bigger because the population of village was increased；on the other side, Shanshang Viallage&rsquo;s religious realms become wilder due to the increase of temple actives. However, for the &quot;five camps&quot;, the east and west side of the deities&rsquo;s emissary did not extend so the Religious Realms can not protect the new village, (2) The distribution of the spiritual field in the Shanzhong village, the &quot;&quot;five camps&quot;&quot; are more closely related to the geographical scope of the residents&rsquo; rotation worship. The tradition of rotation worship with the concept of grouping is gradually blurring, and the old people are blurring; Understand why there is a possibility that there is a fault in the inheritance of religious beliefs; (3) Villagers in the mountains have different interpretations of deities in different religious fields, and it is generally difficult to understand the origin and background of deities, older than those who understand; older than middle-aged; more young Unrecognizable to the gods; (4) The significance of the gods in different religious fields is more related to the early life environment of the villagers in the mountains. The elderly have significant health and safety; the middle-aged people seek wealth and career; the young people seek smooth schooling .Then refer to the above research results to make research suggestions.</p> <p>&nbsp;</p>

scholarly journals The association between childhood neighborhood relationship and mental health in middle and later life: Evidence from the China Health and Retirement Longitudinal Study

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Jian Sun ◽  
Hongye Luo ◽  
Chaofan Li ◽  
Qianqiang Wang
Keyword(s):  
Mental Health ◽  
Older Adults ◽  
Longitudinal Study ◽  
Regression Models ◽  
Later Life ◽  
Ordinary Least Squares ◽  
Middle Aged ◽  
Logit Regression ◽  
Neighborhood Relationship ◽  
Research Gap

Abstract Background It is unclear that whether childhood neighborhood relationship is associated with mental health among middle-aged and older adults. To overcome this research gap, this study aimed to investigate the association between childhood neighborhood relationship and mental health among the middle-aged and older adults in China. Methods The data of this study was sourced from the 2014 and 2015 waves of China Health and Retirement Longitudinal Study. We used ordinary least squares and logit regression models to explore the association between childhood neighborhood relationship and mental health among the middle-aged and older adults in China. Results The regression results indicate that the middle-aged and older adults who lived in place where neighbors had close-knit relationships at childhood was significantly associated with decreased odds of suffering from depressive symptoms (OR = 0.4259, p < 0.001). Furthermore, compared to the middle-aged and older adults who lived in place where neighbors were not close-knit at childhood, those who lived in place where neighbors were close-knit at childhood had a reduced CES–D score (coefficient = − 2.7822, p < 0.001). Conclusion This study demonstrates the importance of living in place where neighbors had close-knit relationships at childhood. The integrated interventions, including maintaining close-knit neighborhood relationships and strengthening the construction of community, may be useful to improve mental health.

scholarly journals Middle-aged Australians’ perceptions of support to reduce lifestyle risk factors: a qualitative study

2020 ◽  
Vol 26 (4) ◽  
pp. 313
Author(s):  
Christine Ashley ◽  
Elizabeth Halcomb ◽  
Susan McInnes ◽  
Karin Robinson ◽  
Elizabeth Lucas ◽  
...  
Keyword(s):  
Risk Factors ◽  
General Practice ◽  
Risk Reduction ◽  
Structured Interview ◽  
Middle Aged ◽  
Aged People ◽  
Lifestyle Risk Factors ◽  
Prevention And Health Promotion ◽  
Lifestyle Risk ◽  
Lifestyle Risk Reduction

Increasingly, middle-aged people are demonstrating lifestyle risk factors that increase their risk of developing chronic disease. Reducing lifestyle risk in middle age can significantly reduce future morbidity and mortality and improve quality of life. Understanding peoples’ perceptions of health support is important to inform health professionals and policymakers regarding strategies to support lifestyle risk reduction. This paper seeks to explore middle-aged Australians’ perceptions of support for lifestyle risk reduction. Thirty-four middle-aged Australians were interviewed using a semi-structured interview schedule. Interviews were audio-recorded, transcribed and analysed using thematic analysis. The overarching theme ‘support for healthy lifestyles’ comprised three subthemes. ‘Engagement with general practice’ highlighted gender differences in why people attend and what impacts their access to general practice. ‘Providing information’ emphasised participants’ experiences of lifestyle risk communication in general practice. Finally, ‘Sources of support’ revealed participants’ current health advice-seeking behaviours. Findings highlight a need for general practices to better engage middle-aged people in behaviour change and educate them about the role of general practice in prevention and health promotion. Consistent messaging across the community and strategies that focus on gender-specific concerns are likely to ensure that middle-aged people are able to make informed choices about seeking support for lifestyle risk reduction.

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