EFFECT OF INTRA-ABDOMINAL PRESSURE ON RESPIRATORY MECHANICS

2007 ◽  
Vol 62 (sup1) ◽  
pp. 78-88 ◽  
Author(s):  
P. Pelosi ◽  
M. Quintel ◽  
M.L.N.G. Malbrain
2012 ◽  
Vol 6 (1) ◽  
pp. 12-15
Author(s):  
Richard Matulewicz ◽  
Antonio R. Gargiulo ◽  
Stephen H. Loring ◽  
Massimo Ferrigno

A 28 year-old obese woman was scheduled for robot-assisted bilateral tubal re-anastomosis under general anesthesia and neuromuscular blockade. As part of a respiratory mechanics study, gastric pressure (Pga) was measured. At the beginning of the operation, the surgeon repeatedly inserted a Veress needle consistently measuring an unusually high opening pressure of 15 mmHg, at a time when Pga was 12.5 mmHg. Based on the elevated Pga values, we inferred that the high opening pressure was a valid intra-peritoneal pressure, rather than a sign of incorrect needle placement; therefore, the surgeon proceeded with uneventful insufflation of the peritoneal cavity. This patient exhibited an unusually high opening intra-abdominal pressure that likely reflected her high degree of central obesity. Simultaneous Pga determination proved valuable in confirming intra-peritoneal location of the tip of Veress needle and may be a viable method of corroborating high opening pressures despite safe needle positions in laparoscopic cases.


2009 ◽  
Vol 132 (1) ◽  
Author(s):  
Michel Behr ◽  
Jeremie Pérès ◽  
Maxime Llari ◽  
Yves Godio ◽  
Yves Jammes ◽  
...  

Over the past decade, road safety research and impact biomechanics have strongly stimulated the development of anatomical human numerical models using the finite element (FE) approach. The good accuracy of these models, in terms of geometric definition and mechanical response, should now find new areas of application. We focus here on the use of such a model to investigate its potential when studying respiratory mechanics. The human body FE model used in this study was derived from the RADIOSS® HUMOS model. Modifications first concerned the integration and interfacing of a user-controlled respiratory muscular system including intercostal muscles, scalene muscles, the sternocleidomastoid muscle, and the diaphragm and abdominal wall muscles. Volumetric and pressure measurement procedures for the lungs and both the thoracic and abdominal chambers were also implemented. Validation of the respiratory module was assessed by comparing a simulated maximum inspiration maneuver to volunteer studies in the literature. Validation parameters included lung volume changes, rib rotations, diaphragm shape and vertical deflexion, and intra-abdominal pressure variation. The HUMOS model, initially dedicated to road safety research, could be turned into a promising, realistic 3D model of respiration with only minor modifications.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Adrian Regli ◽  
Siavash Ahmadi-Noorbakhsh ◽  
Gabrielle Christine Musk ◽  
David Joseph Reese ◽  
Peter Herrmann ◽  
...  

Abstract Background Intra-abdominal hypertension (IAH) is common in critically ill patients and is associated with increased morbidity and mortality. High positive end-expiratory pressures (PEEP) can reverse lung volume and oxygenation decline caused by IAH, but its impact on alveolar overdistension is less clear. We aimed to find a PEEP range that would be high enough to reduce atelectasis, while low enough to minimize alveolar overdistention in the presence of IAH and lung injury. Methods Five anesthetized pigs received standardized anesthesia and mechanical ventilation. Peritoneal insufflation of air was used to generate intra-abdominal pressure of 27 cmH2O. Lung injury was created by intravenous oleic acid. PEEP levels of 5, 12, 17, 22, and 27 cmH2O were applied. We performed computed tomography and measured arterial oxygen levels, respiratory mechanics, and cardiac output 5 min after each new PEEP level. The proportion of overdistended, normally aerated, poorly aerated, and non-aerated atelectatic lung tissue was calculated based on Hounsfield units. Results PEEP decreased the proportion of poorly aerated and atelectatic lung, while increasing normally aerated lung. Overdistension increased with each incremental increase in applied PEEP. “Best PEEP” (respiratory mechanics or oxygenation) was higher than the “optimal CT inflation PEEP range” (difference between lower inflection points of atelectatic and overdistended lung) in healthy and injured lungs. Conclusions Our findings in a large animal model suggest that titrating a PEEP to respiratory mechanics or oxygenation in the presence of IAH is associated with increased alveolar overdistension.


2001 ◽  
Vol 18 (Supplement 21) ◽  
pp. 113
Author(s):  
P. Pelosi ◽  
J. P. Meinhardt ◽  
P. Caironi ◽  
M. Quintel ◽  
L. Gattinoni

2017 ◽  
Vol 42 ◽  
pp. 387-388
Author(s):  
Natalia Pedrosa Goulart de Andrade ◽  
Gabrielle Caroline Castanheira de Souza ◽  
Melissa Sibinelli ◽  
Juliana Tavares Neves Bernardi ◽  
Paula de Moura Piovesana ◽  
...  

2021 ◽  
pp. 089686082098367
Author(s):  
Qandeel H Soomro ◽  
Vikramjit Mukherjee ◽  
Richard Amerling ◽  
Nina Caplin

Patients with kidney failure and acute respiratory distress syndrome (ARDS) requiring prone position have not been candidates for peritoneal dialysis (PD) due to concern with increased intra-abdominal pressure, reduction in respiratory system compliance and risks of peritoneal fluid leaks. We describe our experience in delivering acute PD during the surge in Covid-19 acute kidney injury (AKI) in the subset of patients requiring prone positioning. All seven patients included in this report were admitted to the intensive care unit with SARS-CoV-2 infection leading to ARDS, AKI and multisystem organ failure. All required renal replacement therapy, and prone positioning to improve ventilation/perfusion mismatch. All seven were able to continue PD despite prone positioning without any detrimental effects on respiratory mechanics or the need to switch to a different modality. Fluid leakage was noted in 71% of patients, but mild and readily resolved. We were able to successfully implement acute PD in ventilator-dependent prone patients suffering from Covid-19-related AKI. This required a team effort and some modifications in the conventional PD prescription and delivery.


2016 ◽  
Vol 52-53 (3-4) ◽  
pp. 62-67
Author(s):  
V.S. Konoplytsky ◽  
◽  
O.O. Lukiyanets ◽  
Keyword(s):  

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