scholarly journals Normal peripheral blood neutrophil numbers accompanying ELANE whole gene deletion mutation

2019 ◽  
Vol 3 (16) ◽  
pp. 2470-2473 ◽  
Author(s):  
Marshall S. Horwitz ◽  
Mercy Y. Laurino ◽  
Siobán B. Keel

Key Points The patient reported here, along with collective observations in the literature, suggest that ELANE deletion does not cause neutropenia. Potential therapeutic genome editing involving knockout of the mutant ELANE allele is therefore not expected to produce neutropenia.

Author(s):  
Elaine Hayes ◽  
David A. Bergin ◽  
Isabel Vega-Carrascal ◽  
Joanne Keenan ◽  
Martin Clynes ◽  
...  

Inflammation ◽  
1996 ◽  
Vol 20 (5) ◽  
pp. 513-522 ◽  
Author(s):  
Hannu Kankaanranta ◽  
Eeva Moilanen ◽  
Tapani Tuomiranta ◽  
Markku Korpela ◽  
Urpo Yli-Kerttula ◽  
...  

2017 ◽  
Vol 28 (6) ◽  
pp. 1611-1621 ◽  
Author(s):  
Helen M. Roberts ◽  
Melissa M. Grant ◽  
Naomi Hubber ◽  
Paul Super ◽  
Rishi Singhal ◽  
...  

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