Long-term treatment of osteoporosis in postmenopausal women: a review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)

2012 ◽  
Vol 28 (3) ◽  
pp. 475-491 ◽  
Author(s):  
C. Cooper ◽  
J.-Y. Reginster ◽  
B. Cortet ◽  
M. Diaz-Curiel ◽  
R.S. Lorenc ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
European Society ◽  
Term Treatment ◽  
Economic Aspects ◽  
Treatment Of Osteoporosis ◽  
International Osteoporosis Foundation ◽  
Long Term Treatment

scholarly journals MANAGEMENT OF ENDOCRINE DISEASE: Atypical femoral fractures: risks and benefits of long-term treatment of osteoporosis with anti-resorptive therapy

2018 ◽  
Vol 178 (3) ◽  
pp. R81-R87 ◽  
Author(s):  
Robert A Adler
Keyword(s):  
Osteoporotic Fracture ◽  
Femoral Fractures ◽  
Osteoporosis Treatment ◽  
Term Treatment ◽  
Atypical Femoral Fractures ◽  
Treatment Of Osteoporosis ◽  
Endocrine Disease ◽  
Long Term Treatment ◽  
Term Management

Modern osteoporosis treatment began in the mid-1990s with the approval of amino-bisphosphonates, anti-resorptive agents that have been shown to decrease osteoporotic fracture risk by about half. In 2005, the first cases of atypical femoral fractures (AFF), occurring in the shaft of the femur, were reported. Since then, more cases have been found, leading to great concern among patients and a dramatic decrease in bisphosphonate prescribing. The pathogenesis and incidence of AFF are reviewed herein. Management and an approach to prevention or early detection of AFF are also provided. Denosumab, a more recently approved anti-resorptive medication has also been associated with AFF. Long-term management of osteoporosis and prevention of fracture are challenging in light of this serious but uncommon side effect, yet with an aging population osteoporotic fracture is destined to increase in frequency.

Long-term treatment with raloxifene, but not bisphosphonates, reduces circulating sclerostin levels in postmenopausal women

Bone ◽  
2011 ◽  
Vol 48 ◽  
pp. S231
Author(s):  
S.J. Bae ◽  
Y.E. Chung ◽  
S.H. Lee ◽  
S.Y. Lee ◽  
S.Y. Kim ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Term Treatment ◽  
Long Term Treatment

P.3.d.016 Olanzapine LAI: hospital days and health economic aspects during long-term treatment: a multi-center mirror study

2014 ◽  
Vol 24 ◽  
pp. S530
Author(s):  
P.A. Karlsson ◽  
M. Javadi ◽  
T. Liljekvist ◽  
C. Lehman ◽  
S. Olsson ◽  
...  
Keyword(s):  
Health Economic ◽  
Term Treatment ◽  
Economic Aspects ◽  
Long Term Treatment ◽  
Hospital Days
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