scholarly journals Red blood cell (RBC) transfusion rates among US chronic dialysis patients during changes to Medicare end-stage renal disease (ESRD) reimbursement systems and erythropoiesis stimulating agent (ESA) labels

2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Katherine A Cappell ◽  
Sanatan Shreay ◽  
Zhun Cao ◽  
Helen V Varker ◽  
Carly J Paoli ◽  
...  
Keyword(s):  
Blood Cell ◽  
Renal Disease ◽  
Red Blood Cell ◽  
End Stage Renal Disease ◽  
Chronic Dialysis ◽  
Dialysis Patients ◽  
Stage Renal Disease ◽  
End Stage ◽  
Rbc Transfusion

scholarly journals Hemodiafiltration improves red blood cell lifespan in patients with end‐stage renal disease

2021 ◽  
Author(s):  
Ying Jiang ◽  
Jiu‐Hong Li ◽  
Jun‐Feng Luo ◽  
Quan‐Sheng Han ◽  
Sheng‐Lang Zhu ◽  
...  
Keyword(s):  
Blood Cell ◽  
Renal Disease ◽  
Red Blood Cell ◽  
End Stage Renal Disease ◽  
Cell Lifespan ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Myelodysplastic syndrome: the other cause of anemia in end-stage renal disease patients undergoing dialysis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Min-Yu Chang ◽  
Sheng-Fung Lin ◽  
Shih-Chi Wu ◽  
Wen-Chi Yang
Keyword(s):  
Blood Cell ◽  
Renal Disease ◽  
Myelodysplastic Syndrome ◽  
Red Blood Cell ◽  
End Stage Renal Disease ◽  
Refractory Anemia ◽  
Research Database ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Abstract In end-stage renal disease (ESRD) patients receiving dialysis, anemia is common and related to a higher mortality rate. Erythropoietin (EPO) resistance and iron refractory anemia require red blood cell transfusions. Myelodysplastic syndrome (MDS) is a disease with hematopoietic dysplasia. There are limited reports regarding ESRD patients with MDS. We aim to assess whether, for ESRD patients, undergoing dialysis is a predictive factor of MDS by analyzing data from the Taiwan National Health Insurance Research Database. We enrolled 74,712 patients with chronic renal failure (ESRD) who underwent dialysis and matched 74,712 control patients. In our study, we noticed that compared with the non-ESRD controls, in ESRD patients, undergoing dialysis (subdistribution hazard ratio [sHR] = 1.60, 1.16–2.19) and age (sHR = 1.03, 1.02–1.04) had positive predictive value for MDS occurrence. Moreover, more units of red blood cell transfusion (higher than 4 units per month) was also associated with a higher incidence of MDS. The MDS cumulative incidence increased with the duration of dialysis in ESRD patients. These effects may be related to exposure to certain cytokines, including interleukin-1, tumor necrosis factor-α, and tumor growth factor-β. In conclusion, we report the novel finding that ESRD patients undergoing dialysis have an increased risk of MDS.

Red blood cell abnormalities and the pathogenesis of anemia in end-stage renal disease

2016 ◽  
Vol 10 (8) ◽  
pp. 778-790 ◽  
Author(s):  
Hara T. Georgatzakou ◽  
Marianna H. Antonelou ◽  
Issidora S. Papassideri ◽  
Anastasios G. Kriebardis
Keyword(s):  
Blood Cell ◽  
Renal Disease ◽  
Red Blood Cell ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Coronary angiography and revascularization in chronic dialysis patients: Analysis of the causes of end-stage renal disease.

1996 ◽  
Vol 29 (7) ◽  
pp. 1139-1142
Author(s):  
Tokuichiro Sugimoto ◽  
Yuki Ohmoto ◽  
Hitoshi Tagawa ◽  
Hajime Saito ◽  
Daisuke Nagata ◽  
...  
Keyword(s):  
Coronary Angiography ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Chronic Dialysis ◽  
Dialysis Patients ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Shortened red blood cell age in patients with end-stage renal disease who were receiving haemodialysis: a cross-sectional study

2020 ◽  
Author(s):  
Koichiro Matsumura ◽  
Toshika Okumiya ◽  
Tetsuro Sugiura ◽  
Nobuyuki Takahashi ◽  
Yoshihiro Yamamoto ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Blood Cell ◽  
Renal Disease ◽  
Red Blood Cell ◽  
End Stage Renal Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background: The causes of anaemia in patients with end-stage renal disease include a relative deficiency in erythropoietin production and complex clinical conditions. We aimed to investigate the underlying mechanisms of anaemia in patients with end-stage renal disease who were undergoing maintenance dialysis by measuring erythrocyte creatine levels.Methods: In a cross-sectional study, we evaluated 69 patients with end-stage renal disease who were receiving haemodialysis (n = 55) or peritoneal dialysis (n = 14). Erythrocyte creatine level, a quantitative marker of mean red blood cell (RBC) age, was measured.Results: The mean RBC age was significantly shorter in the haemodialysis group than in the peritoneal dialysis group (47.7 days vs. 59.8 days, p<0.0001), although the haemoglobin levels were comparable between the groups. A Spearman correlation coefficient analysis revealed that shortened RBC age positively correlated with transferrin saturation (r = 0.54), ferritin level (r= 0.47), and haptoglobin level (r = 0.39) but inversely related with reticulocyte (r = −0.36), weekly doses of erythropoiesis-stimulating agents (ESAs; r = −0.62), erythropoietin resistance index (r = −0.64), and intradialytic ultrafiltration rate (r = −0.32).Conclusions: Shortened RBC age was observed in patients who were receiving maintenance haemodialysis and was associated with iron deficiency, greater haptoglobin consumption, higher ESA requirements, and poor erythropoietin responsiveness, as well as with greater intradialytic fluid extraction.

scholarly journals Shortened red blood cell age in patients with end-stage renal disease who were receiving haemodialysis: a cross-sectional study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Koichiro Matsumura ◽  
Toshika Okumiya ◽  
Tetsuro Sugiura ◽  
Nobuyuki Takahashi ◽  
Yoshihiro Yamamoto ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Blood Cell ◽  
Renal Disease ◽  
Red Blood Cell ◽  
End Stage Renal Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background The causes of anaemia in patients with end-stage renal disease include a relative deficiency in erythropoietin production and complex clinical conditions. We aimed to investigate the underlying mechanisms of anaemia in patients with end-stage renal disease who were undergoing maintenance dialysis by measuring erythrocyte creatine levels. Methods In a cross-sectional study, we evaluated 69 patients with end-stage renal disease who were receiving haemodialysis (n = 55) or peritoneal dialysis (n = 14). Erythrocyte creatine level, a quantitative marker of mean red blood cell (RBC) age, was measured. Results The mean RBC age was significantly shorter in the haemodialysis group than in the peritoneal dialysis group (47.7 days vs. 59.8 days, p < 0.0001), although the haemoglobin levels were comparable between the groups. A Spearman correlation coefficient analysis revealed that shortened RBC age positively correlated with transferrin saturation (r = 0.54), ferritin level (r = 0.47), and haptoglobin level (r = 0.39) but inversely related with reticulocyte (r = − 0.36), weekly doses of erythropoiesis-stimulating agents (ESAs; r = − 0.62), erythropoietin resistance index (r = − 0.64), and intradialytic ultrafiltration rate (r = − 0.32). Conclusions Shortened RBC age was observed in patients who were receiving maintenance haemodialysis and was associated with iron deficiency, greater haptoglobin consumption, higher ESA requirements, and poor erythropoietin responsiveness, as well as with greater intradialytic fluid extraction.

Application of Reticulocyte-Based Estimation of Red Blood Cell Lifespan in Anemia Management of End-Stage Renal Disease Patients

2020 ◽  
Vol 22 (2) ◽  
Author(s):  
Ly Minh Nguyen ◽  
Calvin J. Meaney ◽  
Gauri G. Rao ◽  
Mandip Panesar ◽  
Wojciech Krzyzanski
Keyword(s):  
Blood Cell ◽  
Renal Disease ◽  
Red Blood Cell ◽  
End Stage Renal Disease ◽  
Anemia Management ◽  
Cell Lifespan ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Progressive Rise in Red Blood Cell Distribution Width Predicts Mortality and Cardiovascular Events in End-Stage Renal Disease Patients

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0126272 ◽  
Author(s):  
Hye Eun Yoon ◽  
Sung Jun Kim ◽  
Hyeon Seok Hwang ◽  
Sungjin Chung ◽  
Chul Woo Yang ◽  
...  
Keyword(s):  
Blood Cell ◽  
Renal Disease ◽  
Red Blood Cell ◽  
End Stage Renal Disease ◽  
Cardiovascular Events ◽  
Cell Distribution ◽  
Distribution Width ◽  
Stage Renal Disease ◽  
End Stage ◽  
Red Blood Cell Distribution
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