scholarly journals The efficacy of fosfomycin trometamol in prevention of postoperative urinary tract infection in pregnant women after endoscopic procedures: open clinical trial

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Mohamed Radwan ◽  
Ayman Hagras ◽  
Salah Nagla ◽  
Nareman Elhamamy ◽  
Mohammed Abou Farha

Abstract Background Fosfomycin tromethamine is recommended (category B) for the treatment of urinary tract infections in pregnant women. We aimed to evaluate the efficacy of single-dose preoperative fosfomycin tromethamine in the prevention of urinary tract infection in pregnant women who underwent lower urinary tract endoscopic surgeries. Methodology The subjects of this study were pregnant women who underwent lower urinary tract endoscopic procedures. All patients received Fosfomycin tromethamine1 packet (3 g) dissolved in water the day before surgery. Routine pre- and postoperative urine analysis and urine cultures were performed when needed. Patients were monitored for urinary tract infections and the side effects of the drug. Moreover, maternal and fetal complications were monitored. Results The study was conducted on 31 pregnant women with a mean age of 24.48 ± 5.35 years. The endoscopic procedures were as follows: 28 (90.3%) DJ ureteric insertions for hydronephrosis, 2 (6.5%) urinary bladder stones, and cystoscopy (3.2%) for gross hematuria. Two (6.5%) patients had postoperative asymptomatic bacteriuria that resolved with oral antibiotic therapy. Conclusion Fosfomycin tromethamine is safe in preventing urinary tract infection and decreases the need for postoperative parenteral antibiotics in pregnant women who require lower urinary tract endoscopic procedures.

2021 ◽  
Vol 9 (11) ◽  
pp. 2784-2788
Author(s):  
Anshu S ◽  
Miharjan K ◽  
Arjun Chand C P ◽  
Arun Pratap

Urinary tract infection (UTI) is a common and painful human illness that is rapidly responsive to modern antibi- otic therapy. UTI is caused by both Gram-negative and Gram-positive bacteria, as well as by certain fungi. The typical symptoms of lower urinary tract infections (LUTI) are dysuria, urinary frequency, and urgency, nocturia, hesitancy, suprapubic discomfort, and gross hematuria. The features of LUTI can be found under the heading Pit- taja Mutrakrichra Lakshana. As Pitta and Vata are the main Doshas involved in the Samprapti of this disease, drugs having Madhura Rasa, Vata-Pitta Samana properties are the ideal choice for the treatment. In Varividar- yadi Kashaya, all the drugs are having Sita Virya and most of the drugs are having Madhura Rasa, Guru- Snigdha Guna, and Madhura Vipaka. So, there is a very need to understand the scope of the usage of Varividaryadi Kashaya in the management of LUTI. Keywords: Urinary tract infection, Pittaja Mutrakrichra, Varividaryadi Kashaya


2018 ◽  
Vol 86 (3) ◽  
pp. 122-125 ◽  
Author(s):  
Riccardo Milandri ◽  
Matteo Maltagliati ◽  
Tommaso Bocchialini ◽  
Chiara Del Prete ◽  
Giampaolo Bianchi ◽  
...  

Introduction and aim: The urodynamic study is an invasive examination that allows a thorough evaluation of the functional activity of the lower urinary tract (bladder, urethra). The execution of urodynamic study exposes the patient to the risk of contracting infections of the lower urinary tract. Prevention of urinary tract infections consists in the avoidance of risk factors and prophylaxis with antimicrobial and non-antimicrobial measures. In this article, we aimed to evaluate the effectiveness of a phytotherapeutic product composed of D-mannose, Hibiscus sabdariffa, and Lactobacillus plantarum in the prevention of infectious events following invasive urodynamic examination. Materials and methods: We selected 100 female consecutive patients (age 19–87 years) that underwent urodynamic invasive procedure. We prescribed 14-day therapy with D-mannose, H. sabdariffa, and L. plantarum to these 100 patients after urodynamic invasive test. After that, we have examined urine cultures and urinary symptoms through telephone interviews and hospital outpatient visits to evaluate the possible presence of urinary tract infections. Results: Urinary tract infections were observed through urine culture in 13% of the selected patients; of the 13 urinary tract infections, 9 were observed in patients with urinary tract recurrent infections in the last year and the other 4 cases were associated with patients with no urinary infection in the last year. Three women reported some urinary symptoms and underwent antibiotic therapy. The other 10 cases were classified as asymptomatic bacteriuria. Three cases were related to patients presenting with pelvic organ prolapse. Eight cases were instead related to significant post-voiding residue (>100). Six patients with urinary tract infection reported constipation in the last year. All patients completed the prescribed therapy due to the affordable price of the product and no side effects have been reported. Conclusion: Our study about the administration of D-mannose, H. sabdariffa, and L. plantarum after invasive urodynamic examination underlined how this phytotherapeutic product can reduce the risk of bacteriuria and urinary tract infection in women.


2021 ◽  
Vol 2021 (4) ◽  
pp. 17-22
Author(s):  
Linda Nazarko

Linda Nazarko details the management of these common infections in primary care settings


2019 ◽  
Vol 68 (5) ◽  
pp. 115-122
Author(s):  
Alexandra M. Khudovekova ◽  
Elena V. Mozgovaya

A urinary tract infection (UTI) during pregnancy remains one of the most important problems of obstetrics, urology, and nephrology. Pregnancy as physiological process contributes to UTI. This is caused by urinary clinical signs changing during pregnancy, approaches to diagnosis and treatment, as well as to the risk of developing urological, obstetric and neonatal complications. This article analyzes contemporary literature over the past 10 years.


Author(s):  
Dominique E. Werter ◽  
Caroline Schneeberger ◽  
Ben Willem J. Mol ◽  
Christianne J.M. de Groot ◽  
Eva Pajkrt ◽  
...  

Objective Urinary tract infections are among the most common infections during pregnancy. The association between symptomatic lower urinary tract infections during pregnancy and fetal and maternal complications such as preterm birth and low birthweight remains unclear. The aim of this research is to evaluate the association between urinary tract infections during pregnancy and maternal and neonatal outcomes, especially preterm birth. Study Design This study is a secondary analysis of a multicenter prospective cohort study, which included patients between October 2011 and June 2013. The population consists of women with low risk singleton pregnancies. We divided the cohort into women with and without a symptomatic lower urinary tract infection after 20 weeks of gestation. Baseline characteristics and maternal and neonatal outcomes were compared between the two groups. Multivariable logistic regression analysis was used to correct for confounders. The main outcome was spontaneous preterm birth at <37 weeks. Results We identified 4,918 pregnant women eligible for enrollment, of whom 9.4% had a symptomatic lower urinary tract infection during their pregnancy. Women with symptomatic lower urinary tract infections were at increased risk for both preterm birth in general (12 vs. 5.1%, adjusted OR 2.5; 95% CI 1.7–3.5) as well as a spontaneous preterm birth at <37 weeks (8.2 vs. 3.7%, adjusted OR 2.3; 95% CI 1.5–3.5). This association was also present for early preterm birth at <34 weeks. Women with symptomatic lower urinary tract infections during pregnancy are also at increased risk of endometritis (8.9 vs. 1.8%, adjusted OR 5.3; 95% CI 1.4–20) and mastitis (7.8 vs. 1.8%, adjusted OR 4.0; 95% CI 1.6–10) postpartum. Conclusion Low risk women with symptomatic lower urinary tract infections during pregnancy are at increased risk of spontaneous preterm birth. In addition, an increased risk for endometritis and mastitis postpartum was found in women with symptomatic lower urinary tract infection during pregnancy. Key Points


Author(s):  
L. Lebid

the review contains information about modern conception of the urinary tract infections in pregnant women, the scheme of treatment and prevention of relapse in view of topical diagnosis and category of the teratogenicity of drugs on the criteria of FDA


Author(s):  
Shikha Pal ◽  
Narendra Kumar Yadav ◽  
Aayush Yadav ◽  
Mandeep, Mahipal

Urinary tract infection (UTI) are common during pregnancy. These most common causative organism is E.coli.1 A urinary tract infection (UTI) is an infection in any part of urinary system including kidney, ureters, bladder and urethra.2 The urinary can be divided into the upper urinary tract and the lower urinary tract. The upper urinary tract consist of the kidney and ureters and lower urinary tract consist of the bladder and the urethra.2  UTI can be classified by anatomic site of involvement into lower and upper urinary tract infection.3 Asymptomatic bacteriuria can lead to the development of cystitis and pyelonephritis. All pregnant women should be screened for bacteriuria and subsequently treated with antibiotics such as Nitrofurantoin, sulfisoxazole,or cephalexin. can be life threatening illness, with the increased risk of Perinatal and Neonatal mobility. Pregnant women with urinary group B Streptococcal infection should be treated and should receive intrapartum prophylactic therapy.


Author(s):  
Koffi Abdoul Koffi ◽  
Edèle Kacou Aka ◽  
Horo Apollinaire ◽  
Alice Mlan Britoh ◽  
Jean Marie Perel Konan

Background: Urinary tract infection is a common pathology during pregnancy due to hormonal and morphological changes. Objective of this study was to improve management of urinary tract infection during prenatal care.Methods: A total of 987 pregnant women who have been in prenatal care have freely accepted to participate in cross-sectional study carried out from 1st May 2016 to 30th April 2017 at Yopougon University Hospital (Abidjan Côte d’Ivoire) were included. Patients were submitted to questionnaire by one of investigators for epidemiological component and then physical examination was carried out by her attending physician for clinical component. Then at laboratory urine was taken for culture after dipstick test.Results: Of the 987 patients included 9.4% had a urinary tract infection of which 81.7% were asymptomatic. Significant risk factors retained were existence of a history of urinary tract infection (OR=0.46; p=0,038) and gestational age of pregnancy (OR=0.44; p=0.05). Urine culture isolated germs were mainly Escherichia Coli (51.6%) and Klebsiella pneumoniaie (23.6%). These germs were all susceptible to cephalosporins. They had resistances of more than 50% to penicillins.Conclusions: Escherichia coli and Klebsiella pneumoniae are most common germs of urinary tract infections in pregnant women. Escherichia coli is not susceptible to penicillins with a resistance of 70% for penicillins except for clavulanic acid amoxicillin. It appears as first choice antibiotic for our prescriptions in case of probabilistic antibiotic therapy.


Sign in / Sign up

Export Citation Format

Share Document