scholarly journals Effectiveness of a physical exercise intervention program in improving functional mobility in older adults after hip fracture in later stage rehabilitation: protocol of a randomized clinical trial (REATIVE Study)

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Camila Astolphi Lima ◽  
Catherine Sherrington ◽  
Adriana Guaraldo ◽  
Suzana Albuquerque de Moraes ◽  
Renata dos Ramos Varanda ◽  
...  
2021 ◽  
pp. 111355
Author(s):  
Piero Biteli ◽  
Sandra Maria Barbalho ◽  
Cláudia Rucco Penteado Detregiachi ◽  
Jesselina Francisco dos Santos Haber ◽  
Eduardo Federighi Baisi Chagas

2018 ◽  
Vol 74 (10) ◽  
pp. 1598-1604 ◽  
Author(s):  
Melissa M Markofski ◽  
Kristofer Jennings ◽  
Kyle L Timmerman ◽  
Jared M Dickinson ◽  
Christopher S Fry ◽  
...  

Abstract Background Essential amino acids (EAA) and aerobic exercise (AE) acutely and independently stimulate skeletal muscle protein anabolism in older adults. Objective In this Phase 1, double-blind, placebo-controlled, randomized clinical trial, we determined if chronic EAA supplementation, AE training, or a combination of the two interventions could improve muscle mass and function by stimulating muscle protein synthesis. Methods We phone-screened 971, enrolled 109, and randomized 50 independent, low-active, nonfrail, and nondiabetic older adults (age 72 ± 1 years). We used a 2 × 2 factorial design. The interventions were: daily nutritional supplementation (15 g EAA or placebo) and physical activity (supervised AE training 3 days/week or monitored habitual activity) for 24 weeks. Muscle strength, physical function, body composition, and muscle protein synthesis were measured before and after the 24-week intervention. Results Forty-five subjects completed the 24-week intervention. VO2peak and walking speed increased (p < .05) in both AE groups, irrespective of supplementation type, but muscle strength increased only in the EAA + AE group (p < .05). EAA supplementation acutely increased (p < .05) muscle protein synthesis from basal both before and after the intervention, with a larger increase in the EAA + AE group after the intervention. Total and regional lean body mass did not change significantly with any intervention. Conclusions In nonfrail, independent, healthy older adults AE training increased walking speed and aerobic fitness, and, when combined with EAA supplementation, it also increased muscle strength and EAA-stimulated muscle protein synthesis. These increases occurred without improvements in muscle mass.


2020 ◽  
Vol 65 (2) ◽  
pp. 150-157
Author(s):  
Pollyana Windmöller ◽  
Emely Teixeira Bodnar ◽  
Julia Casagrande ◽  
Fernanda Dallazen ◽  
Juliana Schneider ◽  
...  

2020 ◽  
Vol 133 (7) ◽  
pp. 848-856.e5 ◽  
Author(s):  
Baris Gencer ◽  
Elisavet Moutzouri ◽  
Manuel R. Blum ◽  
Martin Feller ◽  
Tinh-Hai Collet ◽  
...  

2019 ◽  
Vol 84 ◽  
pp. 105789 ◽  
Author(s):  
Elizabeth M. Hudak ◽  
Jennifer Bugos ◽  
Ross Andel ◽  
Jennifer J. Lister ◽  
Ming Ji ◽  
...  

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Wagner Rodrigues Martins ◽  
Marisete Peralta Safons ◽  
Martim Bottaro ◽  
Juscelino Castro Blasczyk ◽  
Leonardo Rios Diniz ◽  
...  

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