scholarly journals Syphilis-associated septic cardiomyopathy: case report and review of the literature

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shiqi Guo ◽  
Qiang Guo

Abstract Background Septic cardiomyopathy has been observed in association with influenza, indicating that not only bacteria but also other infective agents can cause this condition. There has been no systematic study as to whether Treponema pallidum infection induces septic cardiomyopathy, and we are the first to report this possibility. Case presentation We report two cases of a 48-year-old man and a 57-year-old man who were diagnosed with syphilis-related septic cardiomyopathy. The diagnosis of cardiomyopathy was made based on elevation of cardiogenic markers and decrease in ejection fraction evaluated by echocardiography. Screen for infective pathogens was negative except for syphilis, which supported our diagnosis. The two patients recovered following effective anti-syphilis treatment and advanced life support technology. Syphilis serology became negative after treatment. Conclusion Syphilis has the potential to cause septic cardiomyopathy. Clinicians should consider Treponema pallidum in cases of septic cardiomyopathy with unknown pathogens. However, the specific pathophysiological mechanism of syphilis-associated septic cardiomyopathy has not been elucidated, and more specific studies are needed.

2019 ◽  
Author(s):  
Ya-ping Zhou ◽  
Ji-Wei Jiang ◽  
Mei-qing Lin ◽  
Mei-Xin Li ◽  
Xiu-Li Shang

Abstract Background Pupillary abnormalities play an important role in identification of neurosyphilis. Among them, Argyll Roberston pupil is most typical and has been mentioned in many reports and studies. However, papers about Adie’s pupil associated with neurosyphilis are extremely rare. In the present study, we report a case of patient with bilateral Adie’s pupils as isolated manifestation of neurosyphilis. Case presentation we describe a 58-year-old retired Chinese woman with bilateral Adie’s pupils. Further evaluation revealed serologically positive for Treponema pallidum particle agglutination (TPPA), chemiluminescence immunoassays (CLIA) and rapid plasma regain (RPR) test (1:16). The Cerebrospinal fluid (CSF) examination revealed pleocytosis, elevated protein, and positive RPR (1:2), TPPA and CLIA. Final diagnosis of Adie’s pupils associated with neurosyphilis was made and other possible causes were excluded. Cephalosporin was used for treatment due to penicillin allergy. Despite effective anti-syphilis treatment, her pupils remained unchanged. Conclusions Adie’s pupil can be caused by neurosyphilis and is one of the most important pupillary changes in early neurosyphilis. Our study further underscore the necessity of syphilis screening in patients with Adie’s pupil due to further treatment consideration.


2021 ◽  
pp. 1-6
Author(s):  
Kadir Oktay ◽  
Dogu Cihan Yildirim ◽  
Arbil Acikalin ◽  
Kerem Mazhar Ozsoy ◽  
Nuri Eralp Cetinalp ◽  
...  

<b><i>Introduction:</i></b> Extraneural metastases of glioblastoma are very rare clinical entities, especially in pediatric patients. Because of their rarity, they can be confused with other pathological processes. <b><i>Case Presentation:</i></b> We report a case of 16-year-old boy with extensive extraneural metastases of glioblastoma. Lung, liver, cervical lymph nodes, skin, and bone metastases were detected in the patient. <b><i>Conclusion:</i></b> We describe the presentation, evaluation, and diagnosis of this rare condition with regard to pertinent literature.


2020 ◽  
Vol 2 (2(May-August)) ◽  
pp. e452020
Author(s):  
Leopoldo Mandic Ferreira Furtado ◽  
José Aloysio da Costa Val Filho ◽  
Bruno Lacerda Sandes ◽  
Plínio Duarte Mendes ◽  
Patrícia Salomé Gouvea Braga

Introduction: Intracranial dermoid cysts are rare, congenital and, benign lesions. The etiology of these lesions is related to an embryonic defect during neurulation. Case presentation: The present study describes a case of a 3-year-old girl with a giant cerebellar dermoid cyst, which initially manifested as hydrocephalus. Discussion: We discuss its epidemiological characteristics as well as diagnostic and therapeutic management. The combination of high clinical suspicion, anamnesis, thorough physical examination, and adequate interpretation of neuroimaging data is crucial for the early diagnosis and timely therapeutic intervention for such cysts. Conclusion: Surgical approach involving complete lesion resection considerably improves prognosis.


2022 ◽  
Vol 20 ◽  
Author(s):  
Mary M Czech ◽  
William Ogden ◽  
Rashmi Batra ◽  
Joseph D Cooper

Background: Multilocular thymic cysts (MTCs) in adults with human immunodeficiency virus (HIV) are rarely reported. Case Presentation: We describe a case of symptomatic MTC in a male with untreated HIV. A presumptive diagnosis was established based on radiographic imaging and biopsy. Pathologic diagnosis and exclusion of malignancy were ultimately confirmed the following thymectomy. In conjunction with starting antiretroviral therapy, the patient recovered well post-operatively with a resolution of his presenting symptoms. Conclusion: Our case report and review of the literature serve to highlight MTCs as an important clinical entity occurring in persons with HIV.


BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Dmitry Batiukov ◽  
V. Podgaiski ◽  
D. Mikulich ◽  
S. Kalinin

Abstract Background Breast augmentation with implants continues to be the most popular aesthetic surgical procedure performed worldwide. Fat grafting may improve the results of breast augmentation and breast reconstruction with implants. However, fat grafting to the breast with implants carries the risk of implant puncture. To our best knowledge this is the first case in which polyurethane implant puncture during fat grafting is described. Case presentation We report multiple bilateral implant punctures with the cannula during fat grafting in a patient who previously underwent breast reconstruction with polyurethane implants. Conclusions Implants that promote tissue ingrowth may be more prone to puncture with the cannula during fat grafting. Specific planning and surgical maneuvers decrease the risk of implant puncture. Level of evidence Level V, case report.


1989 ◽  
Vol 79 (4) ◽  
pp. 186-189 ◽  
Author(s):  
JH Bonk ◽  
MA Tozzi

The diagnosis of a congenital talonavicular coalition is one that often may be little more than an incidental radiographic finding. However, the acute onset of vague midfoot symptomatology secondary to a minor traumatic event may reveal this rarely reported condition on further clinical examination. The authors present a description of the characteristic historical and clinical features of talonavicular coalitions, current diagnostic and treatment modalities available, and a case presentation of an acute painful talonavicular synostosis in an adolescent male athlete.


2021 ◽  
pp. 1-3
Author(s):  
Paula Pilar Morales Cejas ◽  
Paula Pilar Morales Cejas ◽  
Yanire Sánchez Medina ◽  
Marta García Berrocal ◽  
Luis Francisco Gómez Perals

Background: Leptomeningeal cysts are a rare complication of childhood fractures, being very rare in adulthood and usually related to previous trauma generated in children. Case Presentation: We present a case of “growing fracture” in a 70-year-old woman with a history of head injury in childhood, who clinically debuted with paresthesia-dysesthesia in the left hemicranium and hypersensitivity and pain in the affected area, and who was treated with surgical treatment. Conclusion: We review the pathogenesis, diagnosis and treatment of this injury today.


2020 ◽  
pp. 1-7
Author(s):  
Aurora Alessandrini ◽  
Giancarlo Brattoli ◽  
Bianca Maria Piraccini ◽  
Ambra Di Altobrando ◽  
Michela Starace

<b><i>Introduction:</i></b> Keratosis follicularis spinulosa decalvans (KFSD) is a rare, X-linked, hereditary disorder of keratinization, characterized by skin involvement and progressive scarring alopecia of scalp, eyebrows, and eyelashes. The diagnosis is helped by the particular clinical features, but pathology is mandatory. <b><i>Case Presentation:</i></b> We described a case of a female patient referred to the outpatient’s hair consultation of our department, in which we performed trichoscopy as a very useful tool for the diagnosis, followed by pathology that confirmed KFSD. <b><i>Conclusion:</i></b> In our article, we underlined the importance of trichoscopy for the diagnosis of this hair disease, with also a review of the literature on diagnosis and treatment.


2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Sonika Patel ◽  
Marla Jalbut ◽  
Kimberly S. Esham ◽  
David Stone

Bone marrow cryptococcosis has been rarely reported in the literature, and there are no established treatment guidelines specific to this AIDS-related complication. The recommended treatment for AIDS-related invasive fungal treatments include amphotericin B and flucytosine which are associated with an array of complications making optimal treatment recommendations difficult. This case presentation represents an example of a patient with newly diagnosed AIDS and bone marrow cryptococcosis, which was successfully managed with an antifungal regimen adjusted to her comorbidities.


Author(s):  
Mami Kobayashi ◽  
Hideaki Yagasaki ◽  
Tomohiro Saito ◽  
Atsushi Nemoto ◽  
Atsushi Naito ◽  
...  

AbstractBackground:Fetal goitrous hypothyroidism is mainly caused by maternal treatment of Graves’ disease. Fetal goiter sometimes compresses the trachea and esophagus and may cause polyhydramnios, preterm labor, complications of labor and delivery, and neonatal respiratory disorder.Case presentation:We report a case of fetal goitrous hypothyroidism in which the mother had Graves’ disease, which was treated with propylthiouracil. Intra-amniotic levothyroxine (L-TConclusions:Previous reports on fetal goitrous hypothyroidism that was treated with intra-amniotic L-T


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