scholarly journals Adding trans-abdominal elastography to the diagnostic tool for an ileal gastrointestinal stromal tumor: a case report

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Wan-Ching Lien ◽  
Po-Chu Lee ◽  
Min-Tsan Lin ◽  
Chih-Heng Chang ◽  
Hsiu-Po Wang

Abstract Background Diagnosis of gastrointestinal stromal tumors (GISTs) in the distal small intestine is difficult by endoscopic ultrasound. This is the first reported case of an ileal GIST, which is diagnosed by transabdominal sonography and strain elastography. Case presentation A 75 y/o woman presented with tarry stool and dizziness. No definite bleeder could be identified by esophagogastroduodenoscopy and colonoscopy. The transabdominal sonography revealed a large heterogeneous tumor involving the muscular layer of the ileum. Strain elastography showed the strain ratio was 6.51. Strain histogram was skewed to the blue side, and mean color value was 230.5, signifying a stiff tumor. GIST was highly suspected. The patient underwent laparoscope-assisted tumor excision and the histological examination confirmed a malignant GIST. The patient was discharged without postoperative event. Conclusion Transabdominal strain elastography could play a role to discriminate small bowel GISTs and other submucosal tumors, especially in the location with difficulty in endoscopic ultrasound.

2016 ◽  
Vol 10 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Ryota Niikura ◽  
Takako Serizawa ◽  
Atsuo Yamada ◽  
Shuntaro Yoshida ◽  
Mariko Tanaka ◽  
...  

The number of cancer patients undergoing dialysis has been increasing, and the number of these patients on chemotherapy is also increasing. Imatinib is an effective and safe therapy for KIT-positive gastrointestinal stromal tumors (GIST), but the efficacy and safety of imatinib in dialysis patients remain unclear. Because clinical trials have not been conducted in this population, more investigations are required. We report on a 75-year-old Japanese man undergoing dialysis who presented with massive tarry stool from a duodenal GIST. The duodenal GIST was 14 cm in diameter with multiple liver and bone metastases. The patient underwent an urgent pancreaticoduodenectomy to achieve hemostasis. After surgery, he was administered imatinib 400 mg/day. No severe adverse event including myelosuppression, congestive heart failure, liver functional impairment, intestinal pneumonia, or Steven-Johnson syndrome occurred, and the liver metastasis remained stable for 4 months. During chemotherapy, hemodialysis continued three times per week without adverse events. We suggest that regular-dose imatinib is an effective and safe treatment in patients with GIST undergoing dialysis. In addition, we present a literature review of the effectiveness and safety of imatinib treatment in dialysis patients.


2005 ◽  
Vol 61 (5) ◽  
pp. AB277
Author(s):  
Gloria Fernández-Esparrach ◽  
Enrique Vázquez-Sequeiros ◽  
Lidia Argüello ◽  
Manel Solé ◽  
Maria Pellisé ◽  
...  

2017 ◽  
Vol 6 (1) ◽  
pp. 55 ◽  
Author(s):  
Andre Ignee ◽  
Christian Jenssen ◽  
Michael Hocke ◽  
Yi Dong ◽  
Wen-Ping Wang ◽  
...  

2003 ◽  
Vol 119 (5) ◽  
pp. 703-708 ◽  
Author(s):  
Edward B. Stelow ◽  
Michael W. Stanley ◽  
Shawn Mallery ◽  
Rebecca Lai ◽  
Bradley M. Linzie ◽  
...  

2008 ◽  
Vol 19 (4) ◽  
pp. 924-934 ◽  
Author(s):  
Jung-Ho Kang ◽  
Joon Seok Lim ◽  
Jie-Hyun Kim ◽  
Woo Jin Hyung ◽  
Yong Eun Chung ◽  
...  

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