Arrest and non-fatal suicide attempts among men: analysis of survey data from the National Survey on Drug Use and Health

Abstract Background Studies have found an association between recent arrest and suicide attempts, but the population-level significance of this link has not been reported. We estimated the population attributable risk percent (PAR%) of self-reported non-fatal suicide attempts based on recent arrest in a national sample of adult men. Methods This study included men aged ≥18 who completed the 2008–2019 National Surveys on Drug Use and Health. The outcome measure was any non-fatal suicide attempts in the past year. The primary independent variable was any arrest in the past year. Major depression and substance use disorders were also included as independent variables for comparison. Descriptive statistics and multivariate logistic regression with postestimation marginal effects ascertained the PAR% of non-fatal suicide attempts for arrest, major depression, and substance use disorders, while controlling for sociodemographic covariates. All analyses applied survey weights. We disaggregated analyses by race/ethnicity. Results In the sample of 220,261 men, arrest accounted for 8.9% (99% CI 5.1 to 12.6%, p < 0.001) of non-fatal suicide attempts, while major depression accounted for 40.3% (99% CI 35.0 to 45.1%. p < 0.001) and substance use disorders for 24.1% (99% CI 17.6 to 30.2%, p < 0.001). After disaggregating by race/ethnicity, arrest accounted for 9.5% (99% CI 4.5 to 14.3%, p < 0.001) of suicide attempts among Non-Hispanic White men and fell short of statistical significance for Non-Hispanic Black men (10.2, 99% CI − 3.0 to 21.6%, p = 0.043) and Hispanic men (8.1, 99% CI − 0.5 to 15.9%, p = 0.016). Conclusions Arrest accounted for nearly one in eleven non-fatal suicide attempts in a national sample of American men, which is by extension about 50,000 suicide attempts per year. Results were similar for Non-Hispanic White, Non-Hispanic Black, and Hispanic men, although there were differences in prevalence of arrest and suicide attempts. Unlike major depression, arrest is an easily identifiable event, and the period after arrest might provide an opportunity to support mental health and coping.

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Stealthing Perpetration and Victimization: Prevalence and Correlates Among Emerging Adults

Journal of Interpersonal Violence ◽

10.1177/0886260519888519 ◽

2019 ◽

pp. 088626051988851

Author(s):

Erin E. Bonar ◽

Quyen M. Ngo ◽

Meredith L. Philyaw-Kotov ◽

Maureen A. Walton ◽

Yasamin Kusunoki

Keyword(s):

Substance Use ◽

Drug Use ◽

Sexual Violence ◽

Binge Drinking ◽

Emerging Adults ◽

Illegal Drug ◽

White Race ◽

Illegal Drug Use ◽

Race Ethnicity ◽

Hispanic White

“Stealthing” is a form of sexual violence wherein a sexual partner purposefully removes a condom during penetration without the receptive partner’s knowledge. Given the role of substance use in sexual violence broadly, we examined demographic and substance use correlates of stealthing perpetration (SP) and victimization (SV) among emerging adults. Participants comprised 2,550 18- to 25-year-olds ( M age = 20.8, SD = 2.3), recruited via social media (48% female; 53.9% non-Hispanic White; 46.0% had another racial/ethnic identity; 67.4% heterosexual; 85.3% had some college education). Unadjusted analyses ( t tests, χ2 analysis) and adjusted logistic regression analyses examined associations between demographics (age, education, race/ethnicity, sexual orientation) and substance use (binge drinking, marijuana use, other illegal drug use, and prescription drug misuse) with male SP and male and female SV. Five percent of males and 18.9% of females reported SV; 6.1% of males reported SP. In adjusted analyses, significant correlates of SP were: non-Hispanic White race/ethnicity (odds ratio [OR] = 0.39), binge drinking (OR = 1.39), cannabis use (OR = 1.37), and other drug use (OR = 1.43). Significant correlates of male SV were: non-Hispanic White race/ethnicity (OR = 0.28), non-heterosexual orientation (OR = 0.24), binge drinking (OR = 1.49), and other illegal drug use (OR = 1.79). Significant correlates of female SV were: older age (OR = 1.13), non-Hispanic White race/ethnicity (OR = 0.57), binge drinking (OR = 1.28), cannabis use (OR = 1.29), and other drug use (OR = 1.22). Consistent with literature linking alcohol to sexual violence, binge drinking correlated with both SV and SP, with other substance use also playing a role. Data are needed to explore these relationships using longitudinal, event-level assessments to investigate the influence of acute intoxication. Interventions to reduce sexually transmitted infections, unintended pregnancy, and sexual assault should include content on stealthing and substance use.

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Suicide Attempts in Substance Abusers: Effects of Major Depression in Relation to Substance Use Disorders

American Journal of Psychiatry ◽

10.1176/appi.ajp.159.9.1600 ◽

2002 ◽

Vol 159 (9) ◽

pp. 1600-1602 ◽

Cited By ~ 75

Author(s):

Efrat Aharonovich ◽

Xinhua Liu ◽

Edward Nunes ◽

Deborah S. Hasin

Keyword(s):

Substance Use ◽

Major Depression ◽

Substance Use Disorders ◽

Suicide Attempts ◽

Substance Abusers

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Epidemiology of Substance use Disorders

10.1093/med/9780190681425.003.0041 ◽

2017 ◽

Author(s):

Denise B. Kandel ◽

Mei-Chen Hu ◽

Pamela C. Griesler ◽

Bradley T. Kerridge ◽

Bridget F. Grant

Keyword(s):

Substance Use ◽

Drug Use ◽

General Population ◽

Substance Use Disorders ◽

Substance Use Disorder ◽

Developmental Stages ◽

Consumption Patterns ◽

Dsm 5 ◽

Problematic Drug ◽

Race Ethnicity

The epidemiology of drug use in the general population includes two distinct streams of research. The more common stream measures consumption patterns by asking individuals whether (and how frequently) they have ever used specific classes of drugs. The second stream measures the extent of problematic drug use by asking individuals about behaviors and symptoms that would meet the criteria for a substance use disorder. This chapter presents data on the epidemiology and phenomenology of substance use disorders from comparative and developmental perspectives, focusing on DSM-5 definitions, prevalence for types of drugs and by age, gender, and race/ethnicity, comorbidity with psychiatric disorders, and developmental stages.

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Lifetime Diagnosis of Major Depression as a Multivariate Predictor of Treatment Outcome for Inpatients with Substance Use Disorders from Abstinence-Based Programs

Annals of Clinical Psychiatry ◽

10.3109/10401239709147787 ◽

1997 ◽

Vol 9 (3) ◽

pp. 127-137 ◽

Cited By ~ 20

Author(s):

Norman Miller ◽

Norman Hoffmann ◽

Fred Ninonuevo ◽

Boris Astrachan

Keyword(s):

Substance Use ◽

Treatment Outcome ◽

Major Depression ◽

Substance Use Disorders ◽

Lifetime Diagnosis

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Interactions of neuroimmune signaling and glutamate plasticity in addiction

Journal of Neuroinflammation ◽

10.1186/s12974-021-02072-8 ◽

2021 ◽

Vol 18 (1) ◽

Author(s):

Cassandra D. Gipson ◽

Scott Rawls ◽

Michael D. Scofield ◽

Benjamin M. Siemsen ◽

Emma O. Bondy ◽

...

Keyword(s):

Substance Use ◽

Drug Use ◽

Substance Use Disorders ◽

Drugs Of Abuse ◽

Treatment Strategies ◽

Glutamate Signaling ◽

Open Questions ◽

Seeking Behavior ◽

Glutamate System ◽

Chronic Use

AbstractChronic use of drugs of abuse affects neuroimmune signaling; however, there are still many open questions regarding the interactions between neuroimmune mechanisms and substance use disorders (SUDs). Further, chronic use of drugs of abuse can induce glutamatergic changes in the brain, but the relationship between the glutamate system and neuroimmune signaling in addiction is not well understood. Therefore, the purpose of this review is to bring into focus the role of neuroimmune signaling and its interactions with the glutamate system following chronic drug use, and how this may guide pharmacotherapeutic treatment strategies for SUDs. In this review, we first describe neuroimmune mechanisms that may be linked to aberrant glutamate signaling in addiction. We focus specifically on the nuclear factor-kappa B (NF-κB) pathway, a potentially important neuroimmune mechanism that may be a key player in driving drug-seeking behavior. We highlight the importance of astroglial-microglial crosstalk, and how this interacts with known glutamatergic dysregulations in addiction. Then, we describe the importance of studying non-neuronal cells with unprecedented precision because understanding structure-function relationships in these cells is critical in understanding their role in addiction neurobiology. Here we propose a working model of neuroimmune-glutamate interactions that underlie drug use motivation, which we argue may aid strategies for small molecule drug development to treat substance use disorders. Together, the synthesis of this review shows that interactions between glutamate and neuroimmune signaling may play an important and understudied role in addiction processes and may be critical in developing more efficacious pharmacotherapies to treat SUDs.

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Prevalence and demographic, substance use, and mental health correlates of fasting among U.S. college students

Journal of Eating Disorders ◽

10.1186/s40337-021-00443-3 ◽

2021 ◽

Vol 9 (1) ◽

Author(s):

Kyle T. Ganson ◽

Rachel F. Rodgers ◽

Stuart B. Murray ◽

Jason M. Nagata

Keyword(s):

Mental Health ◽

College Students ◽

Substance Use ◽

Eating Disorder ◽

Suicidal Ideation ◽

Drug Use ◽

Illicit Drug ◽

Men And Women ◽

The Past ◽

Self Injury

Abstract Background Fasting is an unhealthy behavior that has been frequently used as part of weight loss attempts. To date, little research has been conducted to determine the prevalence and substance use and mental health correlates of fasting among college students. Therefore, the aim of this study was to estimate the prevalence and associations between any (≥ 1 time) and regular (≥ 13 times) occurrences of fasting in the past 4 weeks and substance use and mental health correlates among a large sample of college students from 2016 to 2020. Methods Data from four academic survey years (2016–2020; N = 8255) of the national (USA) Healthy Minds Study were analyzed. Unadjusted prevalence of any and regular fasting by survey year and gender was estimated. Multiple logistic regression analyses were conducted to estimate the associations between any and regular fasting and the demographic (age, body mass index, race/ethnicity, sexual orientation, highest parental education), substance use (cigarette use, marijuana use, other illicit drug use, alcohol use), and mental health (depression, anxiety, eating disorder symptoms, suicidal ideation, non-suicidal self-injury) correlates. Results Any fasting in the past 4 weeks was common among both men (14.77%) and women (18.12%) and significantly increased from 2016 (10.30%) to 2020 (19.81%) only among men. Regular fasting significantly increased among both men and women from 2016 (men: 1.46%; women: 1.79%) to 2020 (men: 3.53%; women: 6.19%). Among men and women, both any and regular fasting in the past 4 weeks were associated with higher odds of all mental health symptoms, including a positive depression, anxiety, and eating disorder screen, suicidal ideation, and non-suicidal self-injury. Among women, but not men, any and regular fasting in the past 4 weeks were associated with higher odds of marijuana use and other illicit drug use (e.g., cocaine, ecstasy). Conclusions The results from this study underscore both the high and increasing prevalence of fasting among a national sample of college students, as well as the substance use and mental health symptoms associated with this behavior. Healthcare professionals both on and off campus should consider screening for fasting behaviors among college students and provide appropriate intervention when needed.

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Abstract 228: National Prevalence of Substance Use Disorders Among Hospitalized Heart Failure Patients

Circulation Cardiovascular Quality and Outcomes ◽

10.1161/circoutcomes.11.suppl_1.228 ◽

2018 ◽

Vol 11 (suppl_1) ◽

Author(s):

Sarah C Snow ◽

Gregg C Fonarow ◽

Joseph A Ladapo ◽

Donna L Washington ◽

Katherine Hoggatt ◽

...

Keyword(s):

Heart Failure ◽

Substance Use ◽

Native American ◽

Drug Use ◽

Substance Use Disorders ◽

Age Groups ◽

Opioid Use ◽

Drug Use Disorders ◽

Increased Risk ◽

Drug Use Disorder

Background: Several cardiotoxic substances contribute to the development of heart failure (HF). The burden of comorbid substance use disorders (SUD) among patients with HF is under-characterized. Objectives: To describe the national burden of comorbid SUD (tobacco, alcohol, or drug use disorders) among hospitalized HF patients in the U.S. Methods: We used data from the 2014 National Inpatient Sample to calculate the proportion of hospitalizations for a primary HF admission with tobacco, alcohol, or drug use disorder diagnoses, accounting for demographic factors. Drug use disorder analysis was further sub-divided into specific illicit substance categories. Results: There were a total of 989,080 HF hospitalizations of which 35.3% (n=348,995) had a documented SUD. Tobacco use disorder (TUD) was most common (n= 327,220, 33.1%) followed by drug use disorder (DUD) (n=34,600, 3.5%) and alcohol use disorder (AUD) (n=34,285, 3.5%). Female sex was associated with less TUD (OR 0.59; 95% CI, 0.58-0.60), AUD (OR 0.23; 95% CI, 0.22-0.25) or DUD (OR 0.58; 95% CI 0.55-0.62). Tobacco, alcohol, cocaine, and opioid use disorders were highest among HF patients age 45 to 55, while cannabis and amphetamine use was highest in those <45 years. Native American race (versus White) was associated with increased risk of AUD (OR 1.67; 95% CI 1.27-2.20). Black race was associated with increased risk of AUD (OR 1.09; 95% CI 1.02-1.16) or DUD (OR 1.63; 95% CI 1.53-1.74). Medicaid insurance (versus Medicare) was associated with greater TUD (OR 1.27; 95% CI 1.23-1.32), AUD (OR 1.74; 95% CI 1.62-1.87), and DUD (OR 2.15; 95% CI 2.01-2.30). Decreasing quartiles of median household income were associated with increasing SUD. Conclusions: Comorbid SUD disproportionately affects certain HF populations, including men, younger age groups, lower SES patients, and race/ethnic minorities. Further research on interventions to improve prevention and treatment of SUD among hospitalized HF patients are needed given the high rates of SUD in this population. Systematically screening hospitalized HF patients for SUD may reveal opportunities for treatment and secondary prevention.

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1A Nationwide Analysis of U.S. Racial/Ethnic Disparities in Emergency Department Patients with Mental Health and Substance Use Disorders

10.21203/rs.3.rs-892560/v1 ◽

2021 ◽

Author(s):

Joanne Weinreb ◽

Penina Gavrilova ◽

Jonathan Avery ◽

Sean M. Murphy ◽

Jyotishman Pathak

Keyword(s):

Mental Health ◽

Substance Use ◽

Substance Use Disorders ◽

Wait Time ◽

Wait Times ◽

Hispanic Patients ◽

Racial Ethnic ◽

Triage Level ◽

Hispanic White ◽

White Patients

Abstract BackgroundRacial and ethnic health disparities have been linked with inequalities in access to health care and outcomes. The present study considers whether inequalities persist between racial/ethnic groups among patients with mental health or substance use disorders who visit the emergency department (ED). MethodsWe analyzed data from the National Hospital Ambulatory Medical Care Survey (NHAMCS) from 2012-2018, assessing health disparities among patients diagnosed with mental health or substance use disorders by observing whether significant differences exist in ED wait time and length of visit (LOV) for patients of different races/ethnicities. Stratified models were performed to further understand the impact of regions across the U.S., year, and triage level on the association analysis. ResultsFrom 2012-2018, non-Hispanic Black and Hispanic patients experienced significantly longer ED wait times and LOV as compared to White patients. Patients with private insurance experienced significantly shorter wait times compared to patients with self-pay, and shorter LOV than those with Medicaid/ Children’s Health Insurance Program, or Medicare. Male patients had significantly longer LOV compared to female patients. We observed year by year differences in wait times of non-Hispanic Black patients with improvement appearing between the years 2013 to 2016, while LOV remained consistently longer. We observed both regional and triage level differences, with the U.S. Northeast presenting with the most disparities. Additionally, we noted a general upward trend of SUD diagnoses. Conclusion Our analysis suggests that while there has been an overall improvement in median ED wait time through the years, non-Hispanic Black and Hispanic patients experience significantly longer ED wait time compared to non-Hispanic White patients. Additionally, non-Hispanic Black and Hispanic patients have a significantly longer ED LOV compared to non-Hispanic White patients.

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