scholarly journals Epithelial-myoepithelial carcinoma: a population-based survival analysis

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Mitchell R. Gore
Keyword(s):  
Survival Analysis ◽  
Population Based ◽  
Myoepithelial Carcinoma ◽  
Epithelial Myoepithelial Carcinoma

Dedifferentiated Epithelial–Myoepithelial Carcinoma

2012 ◽  
Vol 21 (5) ◽  
pp. 514-519 ◽  
Author(s):  
Aaron R. Baker ◽  
Sara E. Ohanessian ◽  
Eelam Adil ◽  
Henry S. Crist ◽  
David Goldenberg ◽  
...  
Keyword(s):  
Myoepithelial Carcinoma ◽  
Epithelial Myoepithelial Carcinoma

scholarly journals Nasal Epithelial Myoepithelial Carcinoma: An Unusual Cause of Epiphora, a Case Report and Review of the Literature

2015 ◽  
Vol 6 (2) ◽  
pp. ar.2015.6.0127 ◽  
Author(s):  
Juliette O. Flam ◽  
Christopher D. Brook ◽  
Rachel Sobel ◽  
John C. Lee ◽  
Michael P. Platt
Keyword(s):  
Case Report ◽  
Physical Examination ◽  
Nasal Cavity ◽  
Surgical Excision ◽  
Myoepithelial Carcinoma ◽  
Review Of The Literature ◽  
Nasal Symptoms ◽  
First Case ◽  
Nasal Tumor ◽  
Epithelial Myoepithelial Carcinoma

Introduction Epithelial myoepithelial carcinoma (EMC) of the nasal cavity is a rare tumor, and here we describe the first case of EMC of the nasal cavity presenting with epiphora. A case presentation and review of the literature is provided. Methods A case report is described of a 63-year-old man who presented with unilateral epiphora and was found via a thorough history and physical examination to have a nasal tumor. The physical examination consisted of an ocular examination, including probing and irrigation, and a detailed nasal examination (anterior rhinoscopy, nasal endoscopy). The nasal examination was prompted by the patient's report of concurrent nasal symptoms during history taking. Immunohistochemistry subsequently identified the nasal tumor as EMC. A literature search was performed to gain insights into similar malignancies of the nasal cavity. Results Eight cases of EMC of the nasal cavity were identified in the literature, none of the patients presented with epiphora. The case presented here resulted in resolution of the patient's symptoms and no evidence of disease after surgical excision. Conclusion Epithelial myoepithelial is a rare salivary gland malignancy that can arise in the nasal cavity. Unilateral epiphora with concurrent nasal symptoms should prompt nasal cavity examination for the possibility of an obstructive tumor.

scholarly journals Ki-67 Index in Salivary Gland Neoplasms

2016 ◽  
Vol 6 (1) ◽  
pp. 1-7
Author(s):  
Suma Kaza ◽  
T Jaya Mastan Rao ◽  
Anupama Mikkilineni ◽  
G Venkata Ratnam ◽  
D Ranga Rao
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Salivary Gland Neoplasms ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Myoepithelial Carcinoma ◽  
Cell Adenoma ◽  
Ki 67 ◽  
Adenoid Cystic ◽  
Epithelial Myoepithelial Carcinoma

Abstract Assessment of proliferation is a means of predicting local recurrence and metastatic potential of malignancies. A mitotic count is not an ideal marker for proliferation in certain situations, such as salivary gland neoplasms. Ki-67 expression as a proliferation marker has been investigated in many human tumors. In the present study, Mitotic index (MI) and Ki-67 index were studied in pleomorphic adenoma, basal cell adenoma, mucoepidermoid carcinoma, adenoid cystic carcinoma epithelial myoepithelial carcinoma, carcinoma ex Pleomorphic adenoma and adenocarcinoma of salivary glands. The results were compared. The MI was similar in benign neoplasms, mucoepidermoid carcinoma and epithelial myoepithelial carcinoma, whereas it was high in carcinoma ex pleomorphic adenoma, adenocarcinoma and adenoid cystic carcinoma. The Ki-67 index was different in basal cell adenoma and pleomorphic adenoma. It was helpful in differentiating high grade and low grade mucoepidermoid carcinoma. It highlighted the malignant behavior of epithelial myoepithelial carcinoma. It was concluded that Ki-67 in benign neoplasms is 5% or less and in malignant ones more than 23% with a few exceptions. In mucoepidermoid carcinoma and epithelial myoepithelial carcinoma, Ki-67 index was found to be a better indicator for aggressiveness. These findings will be presented in this paper, with review of literature. How to cite this article Kaza S, Rao TJM, Mikkilineni A, Ratnam GV, Rao DR. Ki-67 Index in Salivary Gland Neoplasms. Int J Phonosurg Laryngol 2016;6(1):1-7.

scholarly journals Epithelial-Myoepithelial Carcinoma of Parotid Gland—A Surprising Clinical Entity

2012 ◽  
Vol 03 (05) ◽  
pp. 274-278 ◽  
Author(s):  
Jaimanti Bakshi ◽  
Grace Budhiraja ◽  
Karan Gupta ◽  
Sourabha K. Patro ◽  
Nalini Gupta
Keyword(s):  
Parotid Gland ◽  
Clinical Entity ◽  
Myoepithelial Carcinoma ◽  
Epithelial Myoepithelial Carcinoma

scholarly journals Sinonasal epithelial-myoepithelial carcinoma: Report of a novel subsite and review of the literature

2018 ◽  
Vol 9 ◽  
pp. 215265671876422 ◽  
Author(s):  
Theodore A. Schuman ◽  
Adam J. Kimple ◽  
Claire H. Edgerly ◽  
Charles S. Ebert ◽  
Adam M. Zanation ◽  
...  
Keyword(s):  
Salivary Glands ◽  
Medical Literature ◽  
Clinical Course ◽  
Myoepithelial Carcinoma ◽  
Review Of The Literature ◽  
Craniofacial Resection ◽  
Primary Location ◽  
Epithelial Myoepithelial Carcinoma ◽  
Ethmoid Sinuses ◽  
Uncommon Neoplasm

Background Epithelial-myoepithelial carcinoma (EMC) is a rare tumor of the major and minor salivary glands. Sinonasal EMC is extremely uncommon and hitherto not described within the frontal or ethmoid sinuses. Objective To present a novel sinonasal subsite and review the literature regarding sinonasal EMC. Methods A case of frontoethmoidal EMC was presented. A medical literature data base was queried from January 1, 1950, to August 8, 2017, for all reports of sinonasal EMC. Results A 69-year-old man underwent combined open and endoscopic craniofacial resection of a right frontoethmoidal EMC, a previously undescribed primary location for this tumor. A comprehensive review of the literature revealed 13 additional cases of sinonasal EMC. Conclusion EMC is an uncommon neoplasm typically found in the major salivary glands; occurrence in the nose or paranasal sinuses is extremely rare. EMC often follows an indolent clinical course, although, in a minority of cases, particularly in large tumors with nuclear atypia, more aggressive behavior may be observed.

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