scholarly journals Effectiveness of beta-tricalcium phosphate in comparison with other materials in treating periodontal infra-bony defects around natural teeth: a systematic review and meta-analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Reham AL Jasser ◽  
Abdulelah AlSubaie ◽  
Fayez AlShehri

Abstract Background Beta-tricalcium phosphate in regenerative surgery has shown promising results in terms of bone gain and new vital bone formation; however, several studies have contradicted this finding. The aim of this study was to evaluate the effectiveness of beta-tricalcium phosphate compared to other grafting materials in the regeneration of periodontal infra-bony defects. Methods Electronic database (Cochrane, MEDLINE, PubMed, Embase, Science Citation Index Expanded) and manual searches for related data were performed up until March 2020. The outcomes were pocket depth reduction, clinical attachment level gain, and amount of bone fill. Results Five studies were selected based on the inclusion criteria. Bone regeneration with beta-tricalcium phosphate was observed to be superior to that with debridement alone but showed comparable results to other bone graft materials in terms of pocket depth reduction, clinical attachment level gain, and bone fill. Regenerative procedures for periodontal infra-bony defects that used beta-tricalcium phosphate in combination with other growth factors yielded superior outcomes. The meta-analysis revealed that for cases with two-wall defects, the use of beta-tricalcium phosphate yielded statistically significant differences in pocket depth reduction and clinical attachment level gain, but not in bone fill. Conclusions Beta-tricalcium phosphate appears to be a promising material for use in periodontal infra-bony defect regeneration around natural teeth. However, randomized clinical trials with larger sample sizes and more controlled study designs are needed to support these findings.

2020 ◽  
Author(s):  
Reham Al-Jasser ◽  
Abdulelah AlSubaie ◽  
Fayez Alshehri

Abstract Background: β-TCP is a synthetic grafting material (alloplasts)that can be used as allografts and xenografts in peridontal periodontal infra-bony defect. However, it is important to compare this material outcomes in such treatments when comparted to others Therefore, the aim of this review is to evaluate the effectiveness of β-TCP in the regeneration of periodontal infra-bony defect. Methods: Three electronic databases (Cochrane, Pubmed, Embase) were searched up to March 2020. The inclusion criteria consist of regeneration of periodontal infra-bony defect via implementation of β-TCP in combination with other bone graft materials. Outcomes consisted of pocket depth reduction, clinical attachment level gain and bone fill. Results: Five studies were included according to inclusion criteria. β-TCP found to be superior than debridement alone while it shown comparable result to other bone grafts materials in term of pocket depth reduction, clinical attachment level gain and bone fill. the outcomes of the regenerative procedures of periodontal infra-bony defect with the use of β-TCP in combination with other growth factors seems to be superior than alone. Conclusion: β-TCP seems to be a promising material to be used in periodontal infra-bony defect regeneration. However, randomized clinical trials with larger sample size and more controlled study design are needed to support the findings.


2010 ◽  
Vol 53 (4) ◽  
pp. 229-234 ◽  
Author(s):  
Sujith Sukumar ◽  
Ivo Dřízhal ◽  
Josef Bukač ◽  
Vladimíra Paulusová ◽  
Shriharsha Pilathadka

Alloplastic bone graft materials are widely been used in combination with barrier membranes to achieve guided tissue regeneration in the treatment of periodontal intrabony defects. This study was designed to evaluate the clinical outcome of a composite material, beta tricalcium phosphate in combination with calcium sulphate in the treatment of periodontal intrabony defects. The combination of these materials is believed to aid in guided tissue regeneration owing to their properties. Thirty nine intrabony defects in 21 patients were treated with Fortoss® Vital (Biocomposites, Staffordshire, UK). Clinical parameters were evaluated including changes in probing depth, clinical attachment level/loss and gingival recession at baseline and one year postoperatively. The mean differences in measurements between the baseline and one year postoperatively are a reduction of 1.98±1.16 mm (p=0.000) in case of probing depth and a gain of 1.68±1.12 mm (p=0.000) in clinical attachment level and an increase of 0.31±0.67 mm (p=0.009) in gingival recession measurements. The study results show that the treatment with a combination of beta tricalcium phosphate and calcium sulphate led to a significantly favorable clinical improvement in periodontal intrabony defects one year postoperatively.


Author(s):  
Ranjita Shrestha Gorkhali ◽  
Shaili Pradhan ◽  
Rejina Shrestha ◽  
Shweta Agrawal ◽  
Krishna Lamicchane ◽  
...  

Introduction: Treatment of periodontal diseases done by surgical therapy depends upon extent and severity of disease. The ultimate goal of periodontal reconstructive surgery is to regenerate tissues destroyed during periodontal disease. Objective: To evaluate the effectiveness of bovine-derived xenograft with collagen membrane in treatment of intrabony defects by comparing it with open flap debridement alone. Methods: This non-randomised controlled trial was conducted after ethical clearance, at Bir hospital from 2018 March to 2019 April. The study recruited 38 patients by convenience sampling, age from 25-44 years, with chronic periodontitis, and willing to sign informed consent. Intrabony defects were treated by open flap debridement with bovine-derived xenograft and bioresorbable collagen membrane (Test group) and open flap debridement alone (Control group). Probing pocket depth, clinical attachment level, gingival recession, oral hygiene status, and gingival status were assessed at baseline and six months. Results: Six months after therapy, in Test group probing pocket depth reduction was 5.2 mm and gain in mean clinical attachment level was 4.3 mm. In Control group, mean probing pocket depth reduction was 3.8 mm and mean gain in clinical attachment level was 2.7 mm. The test treatment resulted in statistically higher probing pocket depth reduction and clinical attachment level gain than Control group. Conclusion: Both therapies resulted in significant probing pocket depth reductions and clinical attachment gains, and treatment with open flap debridement with bovine-derived xenografts and collagen membrane resulted in significantly higher probing pocket depth reduction and clinical attachment gain than treatment with open flap debridement alone.


2011 ◽  
Vol 54 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Sujith Sukumar ◽  
Ivo Dřízhal ◽  
Vladimíra Paulusová ◽  
Josef Bukač

The study was designed to evaluate the clinical outcome of a composite material, beta-tricalcium phosphate in combination with calcium sulphate, in the treatment of periodontal intrabony defects. The combination of these materials is believed to aid in guided tissue regeneration owing to their properties. A total of 47 teeth with intrabony defects in 26 periodontitis patients were treated with Fortoss® Vital (Biocomposites, Staffordshire, UK). Clinical parameters were evaluated which included changes in probing depth, clinical attachment level/loss and gingival recession at the baseline and 2 years postoperatively. The mean differences in measurements between the baseline and 2 years postoperatively were a reduction of 2.07±1.14 mm (p=0.000) in case of probing depth and a gain of 1.93±1.36 mm (p=0.000) in clinical attachment level; but an increase of 0.14±0.73 mm (p=0.571) in gingival recession. The study results show that the treatment with a combination of beta tricalcium phosphate and calcium sulphate led to a significantly favorable clinical improvement in periodontal intrabony defects 2 years after the surgery.


2007 ◽  
Vol 21 (4) ◽  
pp. 348-354 ◽  
Author(s):  
Marcio Dias Giollo ◽  
Patrícia Moura Valle ◽  
Sabrina Carvalho Gomes ◽  
Cassiano Kuchenbecker Rösing

The aim of this study was to evaluate retrospectively the periodontal conditions of teeth with fixed crowns that had been in place from 3 to 5 years before the study was conducted. Forty individuals were recalled for a follow-up visit. Full-mouth clinical examinations were carried out and Visible Plaque Index (VPI), Gingival Bleeding Index (GBI), Probing Pocket Depth (PPD), and clinical attachment level (CAL) were assessed in 6 sites per tooth. Parallel radiographs were also taken and blindly analyzed by a digital caliper (distance between the apex and the bone crest). BANA tests were performed. A contra-lateral sound tooth was considered the control. Mean values were obtained and Wilcoxon and paired sample t tests were used to compare the test and control sites. Crowns had a mean VPI value of 30.42% as compared to 49.17% for sound teeth. The GBI was 33.33% and 26.25% for test and control teeth respectively. Assessment of PPD revealed values of 2.30 and 2.14 mm, and assessment of CAL revealed averages of 2.02 and 1.89 mm for test and control teeth respectively. The mean values for radiographic distances were 12.73 and 13.67 mm, and for the BANA test, 67.50 and 50.00 for sound and crowned teeth, respectively. Statistically significant differences were observed for all parameters except for CAL and for the BANA test. It may be concluded that, with the methods used in the present study, crowns may be associated with more signs of inflammation, however not with periodontal breakdown.


Author(s):  
Harish Kumar Shah ◽  
Shivalal Sharma ◽  
Khushboo Goel ◽  
Sajeev Shrestha ◽  
Surya Raj Niraula

Background: : Chronic periodontitis is one of the most common form of periodontal diseases which either require non-surgical periodontal therapy or open flap debridement-surgical therapy or both. To date, it is unclear as of how much changes occur after NSPT or OFD and which therapy provides the best outcome in chronic periodontitis having probing pocket depth ≥ 5-7 mm. Aim: The aim of this randomized controlled clinical trial was to evaluate the Probing Pocket Depth and Clinical Attachment Level between NSPT and OFD in chronic periodontitis patients. Materials and Methods: A total of 52 healthy patients with PPD ≥ 5-7 mm were included in the present study. Half of the patients assigned for the NSPT and half in the OFD group. The PPD and CAL were measured at baseline, three and six months. Independent sample t-test was used to compare the change in mean PPD and CAL between NSPT and OFD group at three and six months, respectively. Results: The difference in the mean decrease of PPD between NSPT and OFD group at three and six months were 0.15 mm (P<0.05) and 0.19 mm (P<0.05), respectively. The difference in the mean gain of CAL between NSPT and OFD group at three and six months were 0.03 mm (p>0.05) and 0.12 mm (P<0.05), respectively. Conclusion: Substantial improvement in periodontal status occurred with both the therapies, however, significantly higher decrease in PPD and gain in CAL were seen with surgical therapy.


2017 ◽  
Vol 28 (3) ◽  
pp. 330-336 ◽  
Author(s):  
Lélis Gustavo Nicoli ◽  
Guilherme José Pimentel Lopes de Oliveira ◽  
Beatriz Maria Valério Lopes ◽  
Cláudio Marcantonio ◽  
Daniela Leal Zandim-Barcelos ◽  
...  

Abstract The aim of this study was to conduct a retrospective evaluation of the survival and success rates of dental implants with acid-etched surfaces after 8-10 years of function. Forty-four patients who received 183 implants 8-10 years ago were evaluated. Clinical examinations were performed around the implants and natural teeth. The following parameters were measured: visible plaque index (VPI), marginal bleeding index (MBI), probing depth (PD), bleeding on probing (BOP) and clinical attachment level (CAL). To considerer an implant as a success case, the following criteria were considered: absence of peri-implant infection and suppuration, absence of implant mobility, absence of persistent pain and dysesthesia and absence of radiolucency around the implant. Overall, 178 implants were categorized as surviving (97.3%), 155 were categorized as successful (84.7%), 5 implants (2.7%) were lost (1 in the maxilla and 4 in the mandible), and 3 implants were not under functional load (2.0 %). 20 implants were diagnosed with peri-implantitis. Thus, the survival rate was 97% and the success rate was 85%. In conclusion, implants with acid-etched surfaces showed high survival and success rates after a period of 8 to 10 years of function.


2010 ◽  
Vol 11 (2) ◽  
pp. 25-32 ◽  
Author(s):  
Rajan Gupta ◽  
Nymphea Pandit

Abstract Aim The aim of this study was to evaluate the efficacy of biphasic calcium phosphate (ossifi®) and bioactive glass in the treatment of periodontal osseous defects clinically and radiographically and compare them with open-flap debridement. Methods and Materials A total of 45 sites in two test groups (test 1, ossifi; test 2, bioactive glass) and a control group (open-flap debridement), in 35 patients, were selected in this study conducted at the department of Periodontics and Oral Implantology, D.A.V.(C) Dental College, Yamuna Nagar, India. Clinical parameters like plaque index, gingival index, pocket depth, and clinical attachment level were recorded at the baseline and at three months and six months postoperatively. Radiological parameters like the amount of defect resolution and the percentage of defect resolution were recorded at the baseline and at three months and six months postoperatively. Results Statistically significant difference in mean values of the plaque index, gingival index, pocket depth reduction, clinical attachment level, gain amount of defect resolution, and percentage of defect resolution were observed in all the groups at subsequent time periods. Conclusion Both test groups showed significant improvement over the control in both the clinical and radiological parameters. Clinical Significance A greater percentage of defect resolution was noticed in test 1 as compared to test 2, followed by the control. Citation Pandit N, Gupta R, Gupta S. A Comparative Evaluation of Biphasic Calcium Phosphate Material and Bioglass in the Treatment of Periodontal Osseous Defects: A Clinical and Radiological Study. J Contemp Dent Pract [Internet]. 2010 March; 11(2):025-032. Available from: http://www.thejcdp.com/journal/view/ volume11-issue2-pandit.


Materials ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 2933
Author(s):  
Carlo Bertoldi ◽  
Luigi Generali ◽  
Pierpaolo Cortellini ◽  
Michele Lalla ◽  
Sofia Luppi ◽  
...  

In the present study, the clinical outcomes obtained using three different protocols of post-operative plaque control for the 4 weeks after surgery were compared. Thirty healthy subjects, presenting at least one periodontal pocket requiring resective surgery, were selected and randomly distributed to three different groups corresponding to respective post-surgical protocols: (A) toothbrushes + chlorhexidine + anti-discoloration system (ADS + CHX); (B) toothbrushes + chlorhexidine (CHX); (C) only toothbrushes. The full-mouth plaque score (FMPS), full-mouth bleeding score (FMBS), probing pocket depth (PPD), recession depth (REC), clinical attachment level (CAL), and bleeding on probing (BoP) were measured in six aspects per tooth (mesio-buccal (MB), buccal (B), disto-buccal (DB), disto-lingual (DL), lingual (L), and mesio-lingual (ML)) at baseline, 3 months, and 6 months after surgery. FMPS and FMBS did not significantly change (p > 0.05), whereas PPD and CAL significantly decreased, and REC significantly increased in all groups during the study (p < 0.05). Clinical results were satisfactory in all cases, with no significant differences between groups 3 months after surgery. Six months after surgery, only PPD-MB was significantly different in the three groups (p < 0.05). Nevertheless, this value was not clinically relevant because the value of PPD-B (about 2 mm) in group C was physiologic. The mechanical plaque control was proven to be fundamental and sufficient in all the six aspects per tooth to guarantee an excellent clinical outcome without the need of chemical plaque control.


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