scholarly journals Uterine rhabdomyosarcoma complicated by cerebral venous thrombosis and uterine inversion in a young woman: case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hongfa Peng ◽  
Jingjing Jiang ◽  
Xianghua Huang
Keyword(s):  
Venous Thrombosis ◽  
Adolescent Girls ◽  
Cerebral Venous Thrombosis ◽  
Actinomycin D ◽  
Surgical Intervention ◽  
Abnormal Uterine Bleeding ◽  
Uterine Neoplasms ◽  
Case Presentation ◽  
Uterine Inversion ◽  
First Case

Abstract Background Uterine rhabdomyosarcoma is an extremely rare malignant tumor that usually affects young women and has a poor prognosis. Case presentation A 19-year-old nulliparous woman presented to the emergency department under sedation due to seizures. Imaging examination revealed cerebral venous thrombosis. During thrombolytic therapy, she developed vaginal bleeding followed by uterine inversion secondary to uterine rhabdomyosarcoma. The inverted uterus was mistaken for a cervical tumour and was removed vaginally. The patient’s disease progressed despite chemotherapy with vincristine, actinomycin D and cyclophosphamide and she died within 6 months. To our knowledge, this is the first case of uterine rhabdomyosarcoma complicated with cerebral venous thrombosis. Conclusions Malignancy is an important diagnostic in patients with cerebral venous thrombosis with no obvious cause. This case demonstrates the importance of considering uterine neoplasms in the differential diagnosis of adolescent girls with abnormal uterine bleeding. Further, careful anatomical evaluation of vaginal masses should be performed prior to surgical intervention.

scholarly journals Completely inverted uterus secondary to uterine rhabdomyosarcoma mistaken for a cervical tumor and removed vaginally: case report and literature review

2020 ◽  
Author(s):  
Jingjing Jiang ◽  
Hongfa Peng
Keyword(s):  
Young Women ◽  
Surgical Intervention ◽  
Sinus Thrombosis ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Uterine Neoplasms ◽  
Cervical Tumor ◽  
Case Presentation ◽  
Uterine Inversion ◽  
Dismal Prognosis

Abstract Background Uterine rhabdomyosarcoma(RMS) is an extremely rare, underrecognized malignant tumor. It usually affects young women and has a dismal prognosis.Case presentation A 19-year-old nulliparous girl presented to our institution with venous sinus thrombosis who subsequently developed complete uterine inversion, which was mistaken for a cervical tumor and removed vaginally. She experienced uncontrollable occurrence of multiple tumors and died within 6 months.Conclusion Our case illustrates the typical presentation and aggressive behavior of uterine RMS. Abnormal uterine bleeding(AUB) in young women should be a sign to screen for uterine neoplasms. Anatomy should be fully evaluated before proceeding toward surgical intervention to ensure the correct procedure is done.

scholarly journals Cerebral venous thrombosis in a patient with Down syndrome and coronavirus disease 2019: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Henry Robayo-Amortegui ◽  
Natalia Valenzuela-Faccini ◽  
Cesar Quecano-Rosas ◽  
Darlyng Zabala-Muñoz ◽  
Michel Perez-Garzon
Keyword(s):  
Risk Factors ◽  
Down Syndrome ◽  
Case Report ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Epidemiological Data ◽  
Thromboembolic Disease ◽  
Hispanic Woman ◽  
Case Presentation ◽  
The World

Abstract Background The new coronavirus disease 2019 pandemic has spread throughout most of the world. Cerebral venous thrombosis is a rare thromboembolic disease that can present as an extrapulmonary complication in coronavirus disease 2019 infection. Case presentation We report the case of a Hispanic woman with Down syndrome who has coronavirus disease 2019 and presents as a complication extensive cerebral venous thrombosis. Conclusions Cerebral venous thrombosis is a rare thromboembolic disease that can present as an extrapulmonary complication in coronavirus disease 2019 infection. In the absence of clinical and epidemiological data, it is important to carry out further investigation of the risk factors and pathophysiological causes related to the development of cerebrovascular thrombotic events in patients with Down syndrome with coronavirus disease 2019 infection.

scholarly journals First reported case of penile prosthesis infection from brucellosis: case report

2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Nabil Nabil Moohialdin ◽  
Ahmad Shamsodini ◽  
Steven K. Wilson ◽  
Osama Abdeljaleel ◽  
Ibrahim Alnadhari ◽  
...  
Keyword(s):  
Case Report ◽  
Broad Spectrum ◽  
Surgical Intervention ◽  
Penile Prosthesis ◽  
Raw Milk ◽  
Prosthesis Infection ◽  
Case Presentation ◽  
First Case ◽  
Milk Ingestion

Abstract Background Infection after the penile prosthesis can be devastating to both the patient and surgeon with various complications and consequences. After introduction of antibiotic-coated implants, the rate of infection has dramatically decreased, but still we see uncommon organisms causing infection. We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. To our knowledge, this is the first reported case of brucellosis penile prosthesis infection. Case presentation We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. A 75-year-old, diabetic male patient presented with penile prosthesis infection 5 months post-penile exchange surgery due to mechanical malfunctioning of 2-piece penile prosthesis which was inserted 11 years ago. The initial treatment with broad spectrum antibiotics did not subside the infection. After diagnosis of brucellosis, the antibiotic was changed to anti-brucellosis (Rifampicin + Tetracycline). The patient improved dramatically and was discharged home with smooth follow-up course. Conclusion Brucellosis can cause infection of penile prosthesis and can be treated with anti-brucellosis antibiotics without necessitating surgical intervention and removal of prosthesis.

scholarly journals Cerebral venous thrombosis secondary to hyperthyroidism: A case report

2018 ◽  
Vol 15 (1) ◽  
pp. 29-31
Author(s):  
Basant Pant ◽  
Malika Bajracharya ◽  
Avinash Chandra ◽  
Ramita Bati ◽  
Reema Rajbhadari ◽  
...  
Keyword(s):  
Case Report ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Thrombus Formation ◽  
Thyroid Function Test ◽  
Transverse Sinus ◽  
Severe Headache ◽  
Cerebral Veins ◽  
First Case ◽  
Red Flag

Cerebral Venous Thrombosis (CVT) is a rare form of Stroke characterized by thrombus formation in the cerebral veins. CVT is a result of various reasons among which the hyperthyroidism is not so frequently encountered. This is probably the first case report published from Nepal. The aim of this case report is to give the message that persistent severe headache in patient with hyperthyroidism can be the red flag and needs to be investigated further. We present a case of a 35 years old female who presented with complaints of severe headache and persistent in nature associated with vomiting since 5 days. She was a diagnosed subacute thryroiditis and under medicine from 1 month before presenting to us. Her Magnetic Resonance Venography (MRV) brain showed venous thrombosis within superior saggital sinus, left transverse sinus and sigmoid sinus. Her thyroid function test showed pretreatment T3 of 2.98 ng/ml T4 of 1.02 mg/ ml and TSH of 0.12 μIU/L. She was kept on anticoagulants and other supportive measures. The patient showed improving status with the conservative management.Nepal Journal of Neuroscience 15:29-31, 2018

scholarly journals Cerebral venous thrombosis secondary to an occult maxillary sinusitis in a young male from sub-Saharan Africa

2019 ◽  
pp. 08-12
Author(s):  
Mazou N Temgoua ◽  
Mickael Essouma ◽  
Larry N Tangie ◽  
Cedric Tsinda ◽  
Drusille Feze Foko ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Acute Stroke ◽  
Cerebral Venous Thrombosis ◽  
Fungal Infections ◽  
Sinus Thrombosis ◽  
Maxillary Sinusitis ◽  
Case Reports ◽  
Sub Saharan Africa ◽  
First Case ◽  
Increased Risk

Cerebral venous thrombosis (CVT) also termed cerebral venous sinus thrombosis (CVST), is a special type of cerebrovascular disease characterized by cerebral venous infarction [1]. As from 1825 when the first case was described by Ribes[2], epidemiological descriptions are still restricted to case reports and small retrospective cross-sectional studies yielding low butincreasing incidence: <10 cases per million per year in 1995 to about 13.2 cases per million per year in 2012.CVT mainly occurs in women of child bearing age, probably owing to the use of oral contraceptive pills, and mostly has an acute or subacute course [1]. It can be categorized as primary/idiopathicand secondary. Secondary CVT can further be classified into infective (mainly due to bacterial or fungal infections) and non-infective CVT; the latterbeing due tocoagulation disorders, neoplasms, procoagulant hemodynamic states, vascularitis,homocystinuria, or head trauma [3].With the advent of antibiotics, the epidemiology of CVT has shifted from predominant infective CVT to predominant non-infective CVT, leading to increased risk of misdiagnosis and delayed treatment [3]. We report occult purulent maxillary sinusitis-related CVT in a male Cameroonian patient who presented with headaches, seizures and acute stroke syndrome. The aim of this paper is to reiterate CVT as the main cause of acute stroke syndrome in young adults irrespective of ethnic origin and sex, and suggest systematic screening of infections in those patients, especially in regions with high rates of infections likesub-Saharan Africa.We describe this case with regard to CARE guidelines.

Coccidioidomycosis Meningitis With Massive Dural and Cerebral Venous Thrombosis and Tissue Arthroconidia

2000 ◽  
Vol 124 (2) ◽  
pp. 310-314 ◽  
Author(s):  
B. K. Kleinschmidt-DeMasters ◽  
Michael Mazowiecki ◽  
Lian A. Bonds ◽  
David L. Cohn ◽  
Michael L. Wilson
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Coccidioides Immitis ◽  
Pathogenic Organism ◽  
The Past ◽  
First Case ◽  
Coagulation Defects ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Thrombotic Tendency

Abstract To our knowledge we report the first case of meningitis from Coccidioides immitis associated with massive dural and cerebral venous thrombosis and with mycelial forms of the organism in brain tissue. The patient was a 43-year-old man with late-stage acquired immunodeficiency syndrome (AIDS) whose premortem and postmortem cultures confirmed C immitis as the only central nervous system pathogenic organism. Death was attributable to multiple hemorrhagic venous infarctions with cerebral edema and herniation. Although phlebitis has been noted parenthetically to occur in C immitis meningitis in the past, it has been overshadowed by the arteritic complications of the disease. This patient's severe C immitis ventriculitis with adjacent venulitis appeared to be the cause of the widespread venous thrombosis. AIDS-related coagulation defects may have contributed to his thrombotic tendency.

scholarly journals Uncontrollable uterine atony after replacement of uterine inversion managed by hysterectomy: a case report

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Daisuke Katsura ◽  
Suzuko Moritani ◽  
Shunichiro Tsuji ◽  
Kounosuke Suzuki ◽  
Kazutaka Yamada ◽  
...  
Keyword(s):  
Uterine Artery Embolization ◽  
Surgical Intervention ◽  
Massive Hemorrhage ◽  
Japanese Woman ◽  
Uterine Atony ◽  
Artery Embolization ◽  
Case Presentation ◽  
Balloon Tamponade ◽  
Uterine Inversion ◽  
Old Japanese

Abstract Background Uterine inversion may cause massive hemorrhage, resulting in maternal deterioration and death. Replacement of the inverted uterus must be performed as soon as possible. As time passes, the inverted uterus becomes atonic and necrotic, and a surgical approach may be required. Case presentation A 27-year-old Japanese woman was admitted to our hospital 4 hours postpartum with increased hemorrhage after the replacement of an inverted uterus. Recurrent inversion was diagnosed, and though the atonic uterus was replaced again by the Johnson maneuver, hemorrhage persisted. Balloon tamponade was not successful in stopping the hemorrhage, and uterine artery embolization was performed. Bleeding resumed the next day on removal of the balloon, and hysterectomy was performed. Massive hemorrhage, coagulopathy, and uterine necrosis caused uterine atony, and the reperfused blood flow on replacement of the ischemic uterus increased hemorrhage. Conclusions Cases of uterine inversion with coagulopathy lasting for more than 4 hours may require a surgical intervention, and uterine replacement may have to be delayed until the maternal hemodynamic condition is stabilized. Uterine replacement under laparotomy may be also be considered due to the risk of increased hemorrhage.

scholarly journals Right Testicular Artery Occlusion and Acute Appendicitis by Angiostrongylus costaricensis

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Luis Enrique Sánchez-Sierra ◽  
Roberto Antonio Martínez-Quiroz ◽  
Héctor S. Antúnez ◽  
Humberto Cabrera-Interiano ◽  
Fernando Josué Barrientos-Melara
Keyword(s):  
Acute Abdomen ◽  
Pediatric Patients ◽  
Surgical Intervention ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Artery Occlusion ◽  
Histopathological Study ◽  
Testicular Artery ◽  
Case Presentation ◽  
First Case

Introduction. Angiostrongylus costaricensis is a nematode from the superfamily Metastrongyloidea, whose etymology is “roundworm that lives in blood vessels”. This parasite can be found from the southern United States to northern Argentina and southern Brazil. In 1983, Morera and Ruiz published the first case of a testicular artery occlusion by A. costaricensis. Case Presentation. A five year old boy presented with eight days of pain, denying trauma backgrounds and followed with an increase of volume. The treatment was a right simply orchiectomy, finding necrosis of the testicle, the biopsy showed reddish-purple aspect and soft consistency. Histologic studies reveled the presence of a worm inside the testicular artery. Conclusion. The diagnosis of A. costaricensis infection should be considered in all pediatric patients, with signs and symptoms of orchitis or acute abdomen, from endemic areas, may cause occlusion of the testicular artery and appendicular artery causing testicular and cecal appendix necrosis, respectively, even putting the patient’s life at risk. The diagnosis is complex, because the clinical manifestations are similar to an orchitis or acute abdomen, therefore, the definitive diagnosis is made during the surgical intervention and histopathological study.

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