scholarly journals Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether–lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tanzania: a randomized controlled trial

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Lwidiko E. Mhamilawa ◽  
Billy Ngasala ◽  
Ulrika Morris ◽  
Eliford Ngaimisi Kitabi ◽  
Rory Barnes ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Plasmodium Falciparum ◽  
Low Dose ◽  
Day Treatment ◽  
Controlled Trial ◽  
Plasmodium Falciparum Malaria ◽  
Parasite Clearance ◽  
Cure Rate ◽  
Randomized Controlled ◽  
Uncomplicated Plasmodium Falciparum Malaria

scholarly journals Randomized Controlled Trial of Fosmidomycin-Clindamycin versus Sulfadoxine-Pyrimethamine in the Treatment of Plasmodium falciparum Malaria

2007 ◽  
Vol 51 (5) ◽  
pp. 1869-1871 ◽  
Author(s):  
Sunny Oyakhirome ◽  
Saadou Issifou ◽  
Peter Pongratz ◽  
Fortune Barondi ◽  
Michael Ramharter ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Plasmodium Falciparum ◽  
Oral Dose ◽  
Randomized Trial ◽  
Single Oral Dose ◽  
Uncomplicated Malaria ◽  
Controlled Trial ◽  
Plasmodium Falciparum Malaria ◽  
Randomized Controlled ◽  
High Degree

ABSTRACT Fosmidomycin-clindamycin therapy given every 12 h for 3 days was compared with a standard single oral dose of sulfadoxine-pyrimethamine. The two treatments showed comparably good tolerabilities and had an identical high degree of efficacy of 94% in a randomized trial carried out with 105 Gabonese children aged 3 to 14 years with uncomplicated malaria. These antimalarials merit further clinical exploration.

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