scholarly journals Malaria Trigram: improving the visualization of recurrence data for malaria elimination

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Cleber Matos de Morais ◽  
Kayo Henrique de Carvalho Monteiro ◽  
Jose Diego Brito-Sousa ◽  
Wuelton Marcelo Monteiro ◽  
Vanderson Souza Sampaio ◽  
...  
Keyword(s):  
Malaria Elimination ◽  
Brazilian Amazon ◽  
Amazon Region ◽  
Primary Data ◽  
Malaria Surveillance ◽  
Historical Representation ◽  
Policy Makers ◽  
Individual Level ◽  
Public Health Professionals ◽  
Brazilian Amazon Region

Abstract Background Although considerable success in reducing the incidence of malaria has been achieved in Brazil in recent years, an increase in the proportion of cases caused by the harder-to-eliminate Plasmodium vivax parasite can be noted. Recurrences in P. vivax malaria cases are due to new mosquito-bite infections, drug resistance or especially from relapses arising from hypnozoites. As such, new innovative surveillance strategies are needed. The aim of this study was to develop an infographic visualization tool to improve individual-level malaria surveillance focused on malaria elimination in the Brazilian Amazon. Methods Action Research methodology was employed to deal with the complex malaria surveillance problem in the Amazon region. Iterative cycles were used, totalling four cycles with a formal validation of an operational version of the Malaria Trigram tool at the end of the process. Further probabilistic data linkage was carried out so that information on the same patients could be linked, allowing for follow-up analysis since the official system was not planned in such way that includes this purpose. Results An infographic user interface was developed for the Malaria Trigram that incorporates all the visual and descriptive power of the Trigram concept. It is a multidimensional and interactive historical representation of malaria cases per patient over time and provides visual input to decision-makers on recurrences of malaria. Conclusions The Malaria Trigram is aimed to help public health professionals and policy makers to recognise and analyse different types of patterns in malaria events, including recurrences and reinfections, based on the current Brazilian health surveillance system, the SIVEP-Malária system, with no additional primary data collection or change in the current process. By using the Malaria Trigram, it is possible to plan and coordinate interventions for malaria elimination that are integrated with other parallel actions in the Brazilian Amazon region, such as vector control management, effective drug and vaccine deployment strategies.

scholarly journals Malaria Trigram: Improving the Visualisation of Recurrence Data for Malaria Elimination

2021 ◽  
Author(s):  
Cleber Matos de Morais ◽  
Kayo Henrique de Carvalho Monteiro ◽  
Jose Diego Brito-Sousa ◽  
Wuelton Marcelo Monteiro ◽  
Vanderson Souza Sampaio ◽  
...  
Keyword(s):  
Malaria Elimination ◽  
Brazilian Amazon ◽  
Amazon Region ◽  
Primary Data ◽  
Effective Vaccine ◽  
Malaria Surveillance ◽  
Historical Representation ◽  
Individual Level ◽  
Brazilian Amazon Region ◽  
Effective Drugs

Abstract Background: Although considerable success in reducing the incidence of malaria has been achieved in Brazil in recent years, an increase in the proportion of cases caused by the harder-to-eliminate Plasmodium vivax parasite can be noted. Recurrences in P. vivax malaria cases are due to new mosquito-bite infections, drug resistance or especially from relapses arising from hypnozoites. As such, new innovative surveillance strategies are needed. The aim of this study was to develop an infographic visualisation tool to improve individual-level malaria surveillance focused on malaria elimination in the Brazilian Amazon.Methods: Action Research methodology was employed to deal with the complex malaria surveillance problem in the Amazon region. Iterative cycles were used, totalling four cycles with a formal validation of an operational version of the Malaria Trigram tool at the end of the process. Further probabilistic data linkage was carried out so that information on the same patients could be linked, allowing for follow-up analysis since the official system was not planned in such way that includes this purpose.Results: An infographic user interface was developed for the Malaria Trigram that incorporates all the visual and descriptive power of the Trigram concept. It is a multidimensional and interactive historical representation of malaria cases historical per patient over time and provides visual input to decision-makers on recurrences of malaria.Conclusions: The Malaria Trigram is aimed to help public health professionals and policy makers to recognise and analyse different types of patterns in malaria events, including recurrences and reinfections, based on the current Brazilian health surveillance system, the SIVEP-Malária system, with no additional primary data collection or change in the current process. By using the Malaria Trigram, it is possible to plan and coordinate interventions for malaria elimination that is integrated with other parallel actions in the Brazilian Amazon region, such as vector control management, developing of an effective drugs for treatment and effective vaccine.

scholarly journals Surgical Site Infection Following Caesarean Section by Acinetobacter Species: A Report from a Hyperendemic Setting in the Brazilian Amazon Region

2021 ◽  
Vol 9 (4) ◽  
pp. 743
Author(s):  
Blenda Gonçalves Cabral ◽  
Danielle Murici Brasiliense ◽  
Ismari Perini Furlaneto ◽  
Yan Corrêa Rodrigues ◽  
Karla Valéria Batista Lima
Keyword(s):  
Caesarean Section ◽  
Surgical Site Infection ◽  
Carbapenem Resistance ◽  
Brazilian Amazon ◽  
Amazon Region ◽  
Site Infection ◽  
Acinetobacter Species ◽  
Brazilian Amazon Region ◽  
Acinetobacter Spp ◽  
The Impact

Surgical site infection (SSI) following caesarean section is associated with increased morbidity, mortality, and significant health care costs. This study evaluated the epidemiological, clinical, and microbiological features of Acinetobacter spp. in women with SSIs who have undergone caesarean section at a referral hospital in the Brazilian Amazon region. This study included 69 women with post-caesarean SSI by Acinetobacter spp. admitted to the hospital between January 2012 and May 2015. The 69 Acinetobacter isolates were subjected to molecular species identification, antimicrobial susceptibility testing, detection of carbapenemase-encoding genes, and genotyping. The main complications of post-caesarean SSI by Acinetobacter were inadequate and prolonged antibiotic therapy, sepsis, prolonged hospitalization, and re-suture procedures. A. baumannii, A. nosocomialis and A. colistiniresistens species were identified among the isolates. Carbapenem resistance was associated with OXA-23-producing A. baumannii isolates and IMP-1-producing A. nosocomialis isolate. Patients with multidrug-resistant A. baumannii infection showed worse clinical courses. Dissemination of persistent epidemic clones was observed, and the main clonal complexes (CC) for A. baumannii were CC231 and CC236 (Oxford scheme) and CC1 and CC15 (Pasteur scheme). This is the first report of a long-term Acinetobacter spp. outbreak in women who underwent caesarean section at a Brazilian hospital. This study demonstrates the impact of multidrug resistance on the clinical course of post-caesarean infections.

scholarly journals Inadequate management of natural ecosystem in the Brazilian Amazon region results in the emergence and reemergence of arboviruses

2001 ◽  
Vol 17 (suppl) ◽  
pp. S155-S164 ◽  
Author(s):  
Pedro F. C. Vasconcelos ◽  
Amélia P. A. Travassos da Rosa ◽  
Sueli G. Rodrigues ◽  
Elizabeth S. Travassos da Rosa ◽  
Nicolas Dégallier ◽  
...  
Keyword(s):  
Environmental Changes ◽  
Epidemiological Data ◽  
Brazilian Amazon ◽  
Host Population ◽  
Amazon Region ◽  
Laboratory Animals ◽  
Natural Ecosystem ◽  
Brazilian Amazon Region ◽  
Mining Dam ◽  
The Impact

A total of 187 different species of arboviruses and other viruses in vertebrates were identified at the Evandro Chagas Institute (IEC) from 1954 to 1998, among more than 10,000 arbovirus strains isolated from humans, hematophagous insects, and wild and sentinel vertebrates. Despite intensive studies in the Brazilian Amazon region, especially in Pará State, very little is known about most of these viruses, except for information on date, time, source, and method of isolation, as well as their capacity to infect laboratory animals. This paper reviews ecological and epidemiological data and analyzes the impact of vector and host population changes on various viruses as a result of profound changes in the natural environment. Deforestation, mining, dam and highway construction, human colonization, and urbanization were the main manmade environmental changes associated with the emergence and/or reemergence of relevant arboviruses, including some known pathogens for humans.

Isolation and characterization of a Pseudomonas aeruginosa from a virgin Brazilian Amazon region with potential to degrade atrazine

2014 ◽  
Vol 21 (24) ◽  
pp. 13974-13978 ◽  
Author(s):  
Ana Flavia Tonelli Fernandes ◽  
Michelle Barbosa Partata da Silva ◽  
Vinicius Vicente Martins ◽  
Carlos Eduardo Saraiva Miranda ◽  
Eliana Guedes Stehling
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Brazilian Amazon ◽  
Amazon Region ◽  
Isolation And Characterization ◽  
Brazilian Amazon Region

Beta-Globin Gene Cluster Haplotypes of Amerindian Populations from the Brazilian Amazon Region

1994 ◽  
Vol 44 (3) ◽  
pp. 142-149 ◽  
Author(s):  
João Farias Guerreiro ◽  
Mauro Silvério Figueiredo ◽  
Marco Antonio Zago
Keyword(s):  
Gene Cluster ◽  
Globin Gene ◽  
Brazilian Amazon ◽  
Amazon Region ◽  
Beta Globin ◽  
Beta Globin Gene ◽  
Globin Gene Cluster ◽  
Brazilian Amazon Region

Surveillance-based estimation of the malaria disease burden in a low endemic state of Punjab, India, targeted for malaria elimination

2021 ◽  
Author(s):  
Jaspreet Kaur ◽  
Taruna Kaura ◽  
Ayush Sharma ◽  
Ashish Kumar ◽  
M K Pangotra ◽  
...  
Keyword(s):  
Malaria Elimination ◽  
Control Strategies ◽  
The State ◽  
Primary Data ◽  
Effective Control ◽  
Malaria Surveillance ◽  
Weighted Estimates ◽  
Malaria Burden ◽  
Routine Surveillance ◽  
Malaria Trends

Abstract Background The state of Punjab in India qualifies for malaria elimination because the number of cases reported through routine surveillance is in decline. However, surveillance system prevalence mainly provides malaria trends. Therefore, a prospective epidemiological study was designed to estimate the malaria burden in the state. Methods District-wise annual parasite incidence (API) was used for identification of three strata, representing high, moderate and low API zones. A total of 0.9 million people from nine districts was under malaria surveillance for 1 y. The weighted estimates of API for the three regions was calculated and combined to give an estimate of API for the total population of the state. Results Based upon the primary data generated, malaria cases from high, moderate and low malaria-endemic areas were estimated to be 3727, 904 and 106, respectively. Further, the total number of malaria cases in the state was estimated to be 4737 (95% CI 4006 to 5469) cases per annum. Conclusion Actual burden of malaria in the state of Punjab, India, is about seven to eight times higher than that reported by routine surveillance activities. However, the state still qualifies for malaria elimination but needs vigorous efforts to strengthen the active surveillance and reporting system along with implementation of effective control strategies to achieve malaria elimination.

scholarly journals Parasitoid diversity (Hymenoptera: Braconidae and Figitidae) on frugivorous larvae (Diptera: Tephritidae and Lonchaeidae) at Adolpho Ducke Forest Reserve, Central Amazon Region, Manaus, Brazil

2009 ◽  
Vol 69 (2) ◽  
pp. 363-370 ◽  
Author(s):  
SGM. Costa ◽  
RB. Querino ◽  
B. Ronchi-Teles ◽  
AMM. Penteado-Dias ◽  
RA. Zucchi
Keyword(s):  
New Records ◽  
Brazilian Amazon ◽  
Amazon Region ◽  
Parasitoid Species ◽  
Forest Reserve ◽  
Natural Reservoir ◽  
Wild Fruits ◽  
Parasitism Rates ◽  
Brazilian Amazon Region ◽  
Plastic Containers

This study aimed to identify parasitoid species of frugivorous larvae and to describe the tritrophic interactions involving wild fruits, frugivorous insects and their natural enemies at Adolpho Ducke Forest Reserve (RFAD) (Manaus, AM, Brazil). Collections were performed in four 1 km² quadrants in the corners of the RFAD. The wild fruits were collected inside the forest in access trails leading to each collection area and in trails that surrounded the quadrants, up to five metres from the trail on each side. The fruits were placed in plastic containers covered with thin fabric, with a vermiculite layer on the base to allow the emergence of flies or parasitoids. Seven Braconidae species were collected, distributed among Opiinae: Doryctobracon areolatus (Szépligeti, 1911), Utetes anastrephae (Viereck, 1913), and Opius sp., and Alysiinae: Asobara anastrephae (Muesebeck, 1958), Phaenocarpa pericarpa Wharton and Carrejo, 1999, Idiasta delicata Papp, 1969, and Asobara sp. Parasitism rates by braconids and figitids are presented. Doryctobracon areolatus was the most frequent, parasitizing the highest number of fly species, and showing the highest parasitism percentage in larvae feeding on Micropholis williamii fruits. The collected figitids belong to Aganaspis nordlanderi Wharton, 1998 and A. pelleranoi (Brethes, 1924). All 15 tritrophic associations are new records for the Brazilian Amazon region. The RFAD is an important natural reservoir of frugivorous larvae parasitoids.

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