scholarly journals Prognostic factors affecting the short-term efficacy of non-surgical treatment of chronic periodontitis: a multilevel modeling analysis

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Hui-Jie Liu ◽  
Bo Wang ◽  
Ao-Chen Wang ◽  
Dan-Hong Zhang ◽  
Cui Mao ◽  
...  

Abstract Background This study is aimed to analyze the prognostic factors affecting the short-term efficacy of non-surgical treatment of patients in periodontitis from stage II to stage IV by the multilevel modeling analysis. Materials and methods A total of 58 patients with chronic periodontitis were included in this study. Patients were clinically explored before and 3 months after the treatment and the difference in probing depth was determined [Reduction of probing depth (Δ PD) = baseline PD – finial probing depth (FPD)] which is considered as the therapeutic evaluation. Three different levels were analyzed: patients, teeth and sites to construct a multi-layer linear model. Results Probing depth (PD) improved significantly compared with that before treatment (p < 0.05), in which FPD was (3.90 ± 1.39) mm, and the ΔPD was (1.79 ± 0.97) mm. Compared with the mesial sites and distal sites of the multi-rooted teeth, the number of PD ≥ 5 mm or PD < 5 mm after the treatment was significantly different (P < 0.05), and the proportion of PD < 5 mm was higher in mesial sites. The null model showed that Δ PD varied greatly between groups at various levels (P < 0.001), with prediction variable of site level, tooth level, and patient level accounted for 66%, 18%, and 16% of the overall difference, respectively. The complete model showed that the Δ PD of smokers was significantly lower than that of non-smokers (P < 0.001). The Δ PD of the mesial and distal sites was larger than that of the buccolingual central site (P < 0.001). The Δ PD of single-rooted teeth was larger than that of multi-rooted teeth (P < 0.001). The baseline PD, tooth mobility (TM), bleeding index (BI), clinical attachment loss (CAL) were significantly negatively correlated with Δ PD (P < 0.001). Conclusions Patients with periodontitis from stage II to stage IV, who were non-smoking, have good compliance, good awareness of oral health, and low percentage sites with PD ≥ 5 mm at baseline, single-rooted teeth with hypomobility, less clinical attachment loss and lower bleeding index and sites of mesial or distal can obtain an ideal short-term efficacy of non-surgical treatment.

2020 ◽  
Author(s):  
Hui-Jie Liu ◽  
Bo Wang ◽  
Ao-Chen Wang ◽  
Dan-Hong Zhang ◽  
Cui Mao ◽  
...  

Abstract Objective This current study is aimed to analyze the prognostic factors affecting the short-term efficacy of non-surgical treatment of patients in periodontitis from stage II to stage IV by the multilevel modelling analysis. Materials and Methods A total of 58 patients of chronic periodontitis were included in this study. Patients were clinically explored before and 3 months after the treatment, with the data of Δ probing depth (PD) [Δ PD = baseline PD – finial probing depth (FPD)] as the outcome variables. All the data were divided into site level, tooth level and patient level to construct a multi-layer linear model. Results Compared with the mesial sites and distal sites of the multi-rooted teeth, the number of PD ≥ 5mm or PD < 5mm after the treatment was significantly different ( P < 0.05), and the proportion of PD < 5mm was higher in mesial sites. The null model showed that Δ PD varied greatly between groups at various levels ( P <0.001), with prediction variable of site level, tooth level, and patient level accounted for 66%, 18%, and 16% of the overall difference, respectively. The complete model showed that the Δ PD of smokers was significantly lower than that of non-smokers ( P < 0.001). The Δ PD of the mesial and distal sites was larger than that of the buccolingual central site ( P < 0.001). The Δ PD of single-rooted teeth was larger than that of multi-rooted teeth ( P < 0.001). The baseline PD, tooth mobility (TM), bleeding index (BI), clinical attachment loss (CAL) were significantly negatively correlated with Δ PD ( P < 0.001). Conclusions Patients with periodontitis from stage II to stage IV, who are non-smoking, have good compliance, good awareness of oral health, and low percentage sites with PD ≥ 5mm at baseline, single rooted teeth with hypomobility, less CAL and lower BI and sites of mesial or distal can obtain an ideal short-term efficacy of non-surgical treatment.


2021 ◽  
Author(s):  
Hui-Jie Liu ◽  
Bo Wang ◽  
Ao-Chen Wang ◽  
Dan-Hong Zhang ◽  
Cui Mao ◽  
...  

Abstract Background: This current study is aimed to analyze the prognostic factors affecting the short-term efficacy of non-surgical treatment of patients in periodontitis from stage Ⅱ to stage Ⅳ by the multilevel modelling analysis.Materials and Methods: A total of 58 patients with chronic periodontitis were included in this study. Patients were clinically explored before and 3 months after the treatment and the difference in probing depth was determined [ Reduction of probing depth (Δ PD) = baseline PD - finial probing depth (FPD)]. Three different levels were analyzed: patients, teeth and sites to construct a multi-layer linear model.Results: Probing depth (PD) improved significantly compared with that before treatment (p < 0.05), in which FPD was (3.90±1.39) mm, and the ΔPD was (1.79±0.97) mm. Compared with the mesial sites and distal sites of the multi-rooted teeth, the number of PD ≥ 5mm or PD < 5mm after the treatment was significantly different (P < 0.05), and the proportion of PD < 5mm was higher in mesial sites. The null model showed that Δ PD varied greatly between groups at various levels (P <0.001), with prediction variable of site level, tooth level, and patient level accounted for 66%, 18%, and 16% of the overall difference, respectively. The complete model showed that the Δ PD of smokers was significantly lower than that of non-smokers (P < 0.001). The Δ PD of the mesial and distal sites was larger than that of the buccolingual central site (P < 0.001). The Δ PD of single-rooted teeth was larger than that of multi-rooted teeth (P < 0.001). The baseline PD, tooth mobility (TM), bleeding index (BI), clinical attachment loss (CAL) were significantly negatively correlated with Δ PD (P < 0.001). Conclusions: Patients with periodontitis from stage Ⅱ to stage Ⅳ, who are non-smoking, have good compliance, good awareness of oral health, and low percentage sites with PD ≥ 5mm at baseline, single rooted teeth with hypomobility, less clinical attachment loss and lower bleeding index and sites of mesial or distal can obtain an ideal short-term efficacy of non-surgical treatment.


2021 ◽  
pp. 76-77
Author(s):  
Nisha Jain ◽  
Rudrax Jindal

The aim of this case series was to assess the efcacy of antimicrobial photodynamic therapy in the treatment of chronic periodontitis. This case series included two subjects with Presence of pocket depth 6 mm or more with clinical attachment loss(CAL) and bleeding on probing (BOP) in minimum of 1 tooth in atleast two quadrants. After full mouth mechanical debridement (SRP), rst site received no further treatment, whereas, second site was subjected to photodynamic therapy. SRP+PDT group showed signicant improvement in (CAL) and reduction in probing depth as compared to SRP group. Therefore, it can be concluded that Photodynamic therapy has its own advantage as an adjunct to SRP in the non surgical treatment of chronic periodontitis,further research for which may be advocated


Author(s):  
Bellia Loredana ◽  
Ruggiero Roberta ◽  
Nicolò Michele

Mechanical surface treatment and removal of the above and subgingival biofilm (Tartar ablation; SRP) are considered the most suitable tools for the treatment of periodontal inflammatory diseases, with the aim of destroying bacterial bioflim, reducing bacteria, and slowing down recolonization by pathogenic microorganisms. Often, however, the only S&RP are not enough, as there are patients who are experiencing relapses. Recently, laser therapy has been suggested as a potential tool to improve the outcome of periodontal non-surgical treatment. The objective of the following study was to evaluate the clinical healing of periodontal pockets treated with mechanical therapy, scaling and root planing, and diode laser application, compared to that obtained with non-surgical mechanical therapy alone. The study was designed as a randomized controlled clinical trial. Patients in the control group (13 patients) underwent conventional non-surgical therapy only, while patients in the test group (17 patients) were associated with conventional non-surgical treatment, a laser irradiation session. At baseline and after 6 months, the parameters of probing depth (PD), bleeding on probing (BOP), gingival recession (REC) were assessed The main variable of this study was the PD (probing depth) FMPS and FMBS at follow-up improved in both groups. The FMPS baseline test group 32.59 ± 6.74 - follow up 12.00 ± 3.16. The baseline of the control group showed 33.00 ± 9.55, the follow up 13.15 ± 4.85 The FMBS baseline test group found 24.29 ± 5.01 while at follow 9.65 ± 2.69. The baseline control group 30.31 ± 7.74, Follow up 11.08 ± 2.33. There is a statistical significance. (P.VALUE 0.0001) There were no significant differences between the groups in terms of PD, CAL and BOP at baseline and at follow-up. PD Test group 4,89±1,58 3,95±0,85 0,0001 Control group 5,02±1,57 4,01±0,86 CAL (mm)Test group 0,89±2,29 0,77±1,91 Control group 0,28±1,38 0,24±1,14 REC Test group 0,19±0,49 0,19±0,51 Control group 0,06±0,29 0,57±029 BOP Test group 51,2% 23,5% Control group 54,0% 20,9% The results showed differences in both baseline and follow-up for REC. Test group 0,19±0,49 0,19±0,51-Control group0,06±0,29 0,57±029 In intra-group analyzes, there are differences between baseline and follow-up for all values, except for REC in the control group. The diode laser can be used as an appropriate device for periodontal treatments, but it can offer additional and significant benefits if used according to appropriate protocols and parameters, and especially if associated with non-surgical, manual and ultrasound periodontal instrumentation, always site-specific , as it is a tool that does not replace traditional methods.


Author(s):  
Fawad Javed ◽  
Abeer S. Al-Zawawi ◽  
Khaled S. Allemailem ◽  
Ahmad Almatroudi ◽  
Abid Mehmood ◽  
...  

In the United States, prevalence of marijuana-use has doubled in the past 2 decades. The aim was to compare the periodontal conditions and whole-salivary IL-17A and IL-23 levels among young adult marijuana-smokers, heavy cigarette-smokers and non-smokers. Self-reported marijuana-smokers, heavy-cigarette-smokers, non-smokers with periodontitis and periodontally-healthy non-smokers were included. Demographic data was recorded and full-mouth plaque index (PI), bleeding on probing (BoP), probing depth (PD) and clinical attachment loss (AL), marginal bone loss (MBL) and missing teeth were recorded. Levels of IL-17A and IL-23 levels were measured in the whole saliva. p < 0.01 was considered statistically significant. Fifteen-marijuana-smokers, 15 heavy-cigarette-smokers, 16 non-smokers-with-periodontitis and 15 periodontally-healthy-non-smokers) were included. The clinicoradiographic parameters were worse among marijuana-smokers (p < 0.01), cigarette-smokers (p < 0.01) and non-smokers-with-periodontitis (p < 0.01) than periodontally-healthy-non-smokers. Marijuana- and cigarette-smokers had Stage-IV/Grade C and non-smokers with periodontitis had Stage-III/Grade-C. Salivary IL-17A and IL-23 levels were higher in marijuana-smokers than cigarette-smokers (p < 0.01) and non-smokers-with-periodontitis (p < 0.01). Whole salivary IL-17A and IL-23 levels were higher among cigarette-smokers than non-smokers with periodontitis (p < 0.01) and periodontally-healthy-individuals (p < 0.01). Marijuana- and heavy cigarette-smokers have comparable clinicoradiographic periodontal statuses. This rejects hypothesis-1. However, whole salivary immunoinflammatory response may be moderately worse in marijuana-smokers compared with heavy cigarette-smokers and non-smoker with periodontitis thereby supporting hypothesis-2.


2019 ◽  
Vol 51 (sup1) ◽  
pp. 135-135
Author(s):  
João Botelho ◽  
Vanessa Machado ◽  
Paulo Mascarenhas ◽  
Maria Alzira Cavacas ◽  
José João Mendes ◽  
...  

Healthcare ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 1070
Author(s):  
Ricardo Andreu ◽  
Sergio Santos-del-Riego ◽  
Francisco Payri

Background: Periodontitis has been associated to systemic diseases and this association could be due to an increase in circulating inflammatory and oxidative stress biomarkers in the periodontal disease. This study aimed to evaluate the relationship between inflammatory and pro-oxidant markers according to different stages of periodontitis. Methods: This cross-sectional study included 70 subjects who were divided into three groups according to periodontitis stage: stage II (n = 22), stage III (n = 30), and stage IV (n = 18). We evaluated periodontal parameters and levels of high-sensitivity C-reactive protein (hsCRP), fibrinogen, and malondialdehyde (MDA) in serum, and 8-hydroxy-2′-deoxyguanosine (8-OHdG) in urine. Results: Serum hsCRP and fibrinogen levels were associated with periodontitis severity, which were higher in stage IV than in stages III and II of periodontitis (p = 0.003 and p = 0.025, respectively). We observed a slight yet insignificant increase in MDA levels related to periodontitis severity. Probing depth and clinical attachment loss were associated with serum fibrinogen and hsCRP levels. However, there were no significant associations between periodontal variables and MDA and 8-OHdG levels. Conclusion: Our data support an association between periodontitis and systemic inflammation, which increases with periodontal disease severity. This indicates the importance of the early diagnosis and treatment of periodontal disease to avoid the development or worsening of systemic inflammatory diseases.


BDJ Open ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
William Ndjidda Bakari ◽  
Diabel Thiam ◽  
Ndeye Lira Mbow ◽  
Anna Samb ◽  
Mouhamadou Lamine Guirassy ◽  
...  

Abstract Purpose To determine the clinical and radiological profile of periodontitis according to the 2018 NCPD, in a Dakar (Senegal) based periodontal clinic. Methods This is a descriptive study based on patient’s records in the periodontology clinic. The study was conducted between November 2018 and February 2020 (15 months). All periodontitis cases were included in the study. Incomplete records (due to lack of radiographic workup or unusable periodontal charting) were excluded. Periodontitis diagnosis was established based on criteria used in the 2018 NCPD. Statistical analysis was carried out using SPSS version 20.0, with the significance threshold set at 0.05. Results A total number of 517 patient records were collected during the study period but only 127 periodontitis records were complete. The mean age of participants was 46.8 ± 13.8 years and 63.8% of participants were males. The mean plaque index and bleeding on probing (BOP) were 74% ± 21.3 and 58.1% ± 25.1, respectively. The mean maximum clinical attachment loss was 8.7 mm ±2.7, with a probing depth greater than 6 mm present in 50.4% of the sample. The median number of missing teeth was 3 (interquartile range 5–1). Pathological mobility was present in 60.6% of the patients and 78.0% had occlusion problems. Bone crest defect at the most affected site was moderate in 52.8% of cases. The ratio of bone loss to age greater than one concerned 66.1% of the sample. Generalised (81.9%), Stage IV (70.1%) and grade C (69.3%) were the most encountered diagnosis. The disease severity was associated with age (r = 0.241; P < 0.001), BOP (r = 0.230; P = 0.013) and the number of teeth with pathological mobility (r = 0.318; P < 0.001). Conclusion Patients with periodontitis in this study had advanced forms of the disease and required multidisciplinary care. Clinical hindsight is necessary to improve this classification.


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