scholarly journals Doses of carbamazepine and valproate in bipolar affective disorder

1997 ◽  
Vol 21 (4) ◽  
pp. 221-223 ◽  
Author(s):  
David Taylor ◽  
Denise Duncan
Keyword(s):  
Affective Disorder ◽  
Acute Treatment ◽  
Bipolar Affective Disorder ◽  
Depressive Illness ◽  
British National Formulary ◽  
National Formulary ◽  
Manic Depressive Illness ◽  
Manic Depressive ◽  
The Uk

Carbamazepine and valproate are now well established treatments for bipolar affective disorder (BAD). Both drugs are used in the acute treatment of mania and, more frequently, as longer-term mood stabilisers. The British National Formulary (BNF, Vol. 32, 1996) provides information on the use of carbamazepine in the ‘prophylaxis of manic depressive illness' and suggests that the ‘usual range’ of doses is between 400 mg and 600 mg daily. No guidance on the use of valproate in BAD is given in the BNF because the drug is not licensed for this indication in the UK.

EFFICACY OF LITHIUM AS ACUTE TREATMENT OF MANIC-DEPRESSIVE ILLNESS

The Lancet ◽  
1971 ◽  
Vol 297 (7713) ◽  
pp. 1319-1325 ◽  
Author(s):  
PeterE. Stokes ◽  
CharlesA. Shamoian ◽  
PeterM. Stoll ◽  
MichaelJ. Patton
Keyword(s):  
Acute Treatment ◽  
Depressive Illness ◽  
Manic Depressive Illness ◽  
Manic Depressive

Affective Illness in First Degree Relatives, Parental Loss and Family Jointness in Depressive Disorders

1973 ◽  
Vol 122 (570) ◽  
pp. 601-602 ◽  
Author(s):  
A. Venkoba Rao
Keyword(s):  
Affective Disorder ◽  
Depressive Disorders ◽  
Parental Death ◽  
Depressive Illness ◽  
Parental Loss ◽  
Manic Depressive Illness ◽  
Affective Illness ◽  
First Degree Relatives ◽  
Manic Depressive

Manic-depressive illness is believed to comprise two different clinical entities: Bipolar and Monopolar. This paper aims to study any differences there may be between monopolar and bipolar depressions in respect of three factors: occurrence of affective disorder (including suicide) in first degree relatives; parental death before the patients' twelfth birthday and the extent of ‘jointness' (Khatri, 1970) of the patients' family.

Some cognitive correlates of affective disorders

1985 ◽  
Vol 15 (2) ◽  
pp. 297-309 ◽  
Author(s):  
Graham Robertson ◽  
Pamela J. Taylor
Keyword(s):  
Affective Disorder ◽  
Affective Disorders ◽  
Depressive Illness ◽  
Cognitive Tests ◽  
Manic Depressive Illness ◽  
Cognitive Correlates ◽  
Manic Depressive ◽  
History Of ◽  
Specific Difficulty

SynopsisSeventy-one men completed a battery of cognitive tests which were designed to reflect verbal analytic and non-verbal holistic functioning. Interest centred around pattern of response. Thirty men were suffering from an affective disorder and forty-one were well. All the men were in prison, the majority awaiting trial. The affective disorder group was subdivided into three categories: men who had a history of manic-depressive illness; a group of unipolar, psychotically depressed men; and men who were regarded as being depressed in reaction to circumstances. All three groups showed specific difficulty in dealing with spatial/holistic tasks, other factors being held constant. They were also found to differ in a number of other respects. The possible significance of these differences is discussed.

Effects of carbamazepine on serum electrolytes in affectively ill patients

1986 ◽  
Vol 16 (2) ◽  
pp. 331-335 ◽  
Author(s):  
Russell T. Joffe ◽  
Robert M. Post ◽  
Thomas W. Uhde
Keyword(s):  
Affective Disorder ◽  
Clinical Improvement ◽  
Serum Sodium ◽  
Prophylactic Treatment ◽  
Depressive Illness ◽  
The Other ◽  
Blood Levels ◽  
Manic Depressive Illness ◽  
Serum Electrolytes ◽  
Manic Depressive

SynopsisThe effects on serum electrolytes of carbamazepine, an acute and prophylactic treatment for manic-depressive illness, were assessed in subjects with primary affective disorder. Carbamazepine caused statistically significant, but clinically insubstantial, reductions in serum sodium and calcium, but not in the other electrolytes measured. Decreases in serum sodium and calcium were not related to carbamazepine dose, blood levels, or the degree of clinical improvement. The theoretical implications of these findings are discussed.

Antonia White and Manic-Depressive Illness

2018 ◽  
Author(s):  
Patricia Moran
Keyword(s):  
Affective Disorder ◽  
Narrative Identity ◽  
Depressive Illness ◽  
Manic Depression ◽  
Manic Depressive Illness ◽  
Complex Interplay ◽  
Manic Depressive ◽  
Identity Narratives ◽  
Autobiographical Fiction ◽  
Emotional Conflicts

Misdiagnosed as suffering from schizophrenia instead of what was bipolar or manic-depressive illness, Antonia White turned repeatedly to psychoanalysis and Catholicism to resolve the emotional conflicts that she believed were the cause of her tumultuous moods, her inexplicable behaviour and her writer’s block. This study rereads White’s writing within the context of manic-depressive illness to show how the misdiagnosis of her illness shaped the identity narratives White constructed in her life-writing and then used as the basis of her strongly autobiographical fiction. White’s self-narratives have skewed critical interpretations of her work; at the same time, her fiction has not been studied as expressive of affective disorder. By contextualising White’s work within the contexts of manic-depression and narrative identity, this study proposes a new model for reading White; documents the complex interplay of biological, psychological and environmental factors involved in affective disorder; and historicises the diagnosis and treatment of White’s illness in medical, psychoanalytic and Catholic contexts.

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