Effects of early-life arsenic exposure on child health and development

2012 ◽  
pp. 223-224
Keyword(s):  
Child Health ◽  
Early Life ◽  
Arsenic Exposure ◽  
Health And Development

Arsenic projects in SE Asia

2016 ◽  
Vol 31 (1) ◽  
Author(s):  
Panida Navasumrit ◽  
Krittinee Chaisatra ◽  
Mathuros Ruchirawat
Keyword(s):  
Early Life ◽  
Arsenic Exposure ◽  
Inorganic Arsenic ◽  
Human Beings ◽  
Disease Outcomes ◽  
Early Life Exposure ◽  
Wide Range ◽  
Southern Thailand ◽  
Health And Development ◽  
The Impact

AbstractEarly life exposure to inorganic arsenic is associated with a wide range of malignant and chronic disease outcomes in humans. Prenatal arsenic exposure may give rise to adverse effects on child health and development as arsenic readily passes through the placenta in human beings. The impact of maternal arsenic exposure on fetal gene expression was conducted in pregnant women living in Southern Thailand. Arsenic exposed newborns had significantly higher levels of arsenic in cord blood, and a set of genes associated with numerous biological pathways, including cell signaling, apoptosis, inflammatory and stress response. A slight increase in promoter methylation of

scholarly journals Digital support systems to improve child health and development in low income settings

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
J Wallenborn ◽  
D Mäusezahl ◽  
A Castellanos ◽  
D McCoy ◽  
C e Zhang ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Cost Effectiveness ◽  
Child Health ◽  
Low Income ◽  
Controlled Trial ◽  
Primary Study ◽  
Developmental Potential ◽  
Digital Platform ◽  
Randomized Controlled ◽  
Health And Development

Abstract About 250 million children under age five are at risk of not reaching their developmental potential due to continued exposure to ill health, malnutrition and lack of appropriate learning environments. A large number of initiatives have been launched in recent years to support early childhood development, with home visiting programs increasingly being recognized as a key strategy for improving child wellbeing. However, the most effective ways to reach families in low income settings remain unclear due to the large expense associated with personal family visits. In this project, we assess the effectiveness and equity of a newly developed digital platform designed to deliver evidence-based, individualized parenting support through automated services. The Afinidata platform uses state-of-the art machine learning algorithms to allow caregivers to get answers to questions about child health and development, while also identifying and promoting age- and development-appropriate activities for parents to support their children. We will collaborate with partners in Peru to rigorously assess the reach, impact and cost effectiveness of this digital platform in a poor rural population through a randomized controlled trial. Our work will follow a mixed-methods evaluation approach with repeated feedback into the Afinidata system. A total of 2,400 newborns will be enrolled in a randomized controlled trial in San Marcos, Peru, and followed up for two years. The primary study outcome will be children's healthy development at 24 months of age assessed through the Bayley Scales of Infant and Toddler Development (BSID-III). Secondary outcomes will be systems utilization, program coverage and cost-effectiveness, as well as caregiver satisfaction. If proven effective, this innovative digital platform may increase global access to low-cost parental support -a widely recognized key strategy for improving child well-being.

scholarly journals Prevalence and Correlates of Vitamin D Deficiency among Young South African Infants: A Birth Cohort Study

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1500
Author(s):  
Jabulani R. Ncayiyana ◽  
Leonardo Martinez ◽  
Elizabeth Goddard ◽  
Landon Myer ◽  
Heather J. Zar
Keyword(s):  
Vitamin D ◽  
Child Health ◽  
Vitamin D Deficiency ◽  
Birth Cohort ◽  
Early Life ◽  
Vitamin D Supplementation ◽  
Sub Saharan Africa ◽  
Health Study ◽  
Birth Cohort Study ◽  
Young Infants

Early-life vitamin D deficiency is associated with adverse child health outcomes, but the prevalence of vitamin D deficiency and its correlates in infants remains underexplored, particularly in sub-Saharan Africa. We aimed to investigate the prevalence of vitamin D deficiency and its correlates among young infants in South Africa. This study included 744 infants, aged 6–10 weeks from the Drakenstein Child Health Study, a population-based birth cohort. Infants were categorized into distinct categories based on serum 25(OH)D concentration level including deficient (<50 nmol/L), insufficient (50–74 nmol/L), and sufficient (≥75 nmol/L). Using multivariable Tobit and logistic regression models, we examined the correlates of serum 25(OH)D3 levels. The overall prevalence of vitamin D deficiency was 81% (95% confidence intervals (CI]) 78–83). Multivariable regression analysis showed that serum 25(OH)D3 concentration was independently associated with study site, socioeconomic status, and sex. Birth in winter and breastfeeding were the strongest predictors of lower serum 25(OH)D3 concentration levels. Compared to non-breastfed children, children breastfed were at higher risk of vitamin D deficiency (AOR, 1.96; 95% CI, 1.04–3.67) and breastfeeding for more than one month was associated with greater likelihood of vitamin D deficiency (AOR, 5.40; 95% CI, 2.37–12.32) and lower vitamin D concentrations (−16.22 nmol/L; 95% CI, −21.06, −11.39). Vitamin D deficiency in infants is ubiquitous, under-recognised, and strongly associated with season of birth and breastfeeding in this setting. Nutritional interventions with vitamin D supplementation in national health programs in low- and middle-income countries are urgently needed to improve early-life vitamin D status in infants.

Controlled Trial of Prenatal Nutrition Supplementation Defended

PEDIATRICS ◽  
1980 ◽  
Vol 66 (4) ◽  
pp. 656-658
Author(s):  
David Rush ◽  
Zena Stein ◽  
Mervyn Susser
Keyword(s):  
Child Health ◽  
Controlled Trial ◽  
Site Visit ◽  
Prenatal Nutrition ◽  
Nutrition Supplementation ◽  
Long Duration ◽  
Health And Development ◽  
Time And Energy

The three commentaries on our recent paper1 by Drs Barness,2 Jacobson,3 and Hegsted4 pose thoughtful questions, which require serious consideration and reply. The study was complicated, of long duration, and it was costly in money, time, and energy. The National Institute of Child Health and Development scrupulously sought to protect its investment; we were site-visited by scientific peers no fewer than seven times. Indeed, both Drs Jacobson and Hegsted served twice on site visit committees.

Child Health and Development

2008 ◽  
pp. 108-111
Author(s):  
Ellen Meryl Schleicher
Keyword(s):  
Child Health ◽  
Health And Development

scholarly journals Parents’ health information seeking behaviour – does the child’s health status play a role?

2020 ◽  
Author(s):  
Isabel Baumann ◽  
Rebecca Jaks ◽  
Dominik Robin ◽  
Sibylle Juvalta ◽  
Julia Dratva
Keyword(s):  
Child Health ◽  
Digital Media ◽  
Health Information ◽  
Information Seeking ◽  
Print Media ◽  
Information Sources ◽  
Personal Network ◽  
Information Seeking Behaviour ◽  
Health And Development ◽  
Search For Information

Abstract BackgroundDigital media are increasingly abundant and being used to seek health information. To date, very little is known about parental seeking behaviour for child health information outside of English-speaking and Nordic countries. Our study “Digital parental counsellors” examines how parents search for health information in digital media, print media and among personal contacts, distinguishing between the search for information about general child health and development and child’s acute illness, and comparing information seeking behaviour by disability status of the child.MethodsA questionnaire was sent to 2573 parents (response rate: 30%) to a population-based sample of parents with children aged 0–2 years (N = 769). We developed a frequency score of use of different information sources and conducted bivariate and multivariate linear regression analyses to describe parental search behaviour and the association with child’s disability status.ResultsThe sample consists of 88% mothers (mean age: 35.7 years SD 4.33). Children’s mean age is 16 months (SD 7.1), 49% of the children are female and 6% have a disability. Parents use digital media significantly more frequently to search for information about general health and development questions than about an acute child’s illness (p < 0.001). In case of acute child’s illness, parents refer to their paediatrician, family members and other personal contacts significantly more frequently than other information sources (p < 0.001). The use of digital media and personal contacts does not significantly vary between parents with and without a disabled child, whereas the use of print media does (p < 0.02). Moreover, irrespective of disability, 45% of parents resort to the Internet prior to a paediatric visit and 27% after a visit when a visit did not answer all questions.ConclusionsDespite the high prevalence of digital media, personal contacts are still the most frequent health information resource for parents with young children. Parents combine all information resources (online, print, personal network) to improve their understanding or check the validity of information received regarding their child’s health. It is thus of utmost importance, that the increasingly accessed digital information parents search for is correct, understandable and addresses parent’s concerns.Trial registration:BASEC Req-2017-00817 (30 October 2017)

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