Unusual Antagonistic Actions of Mixtures of Vasoactive Intestinal Peptide, Thyroid-Stimulating Antibodies, and Cholera Toxin on Adenosine 3’,5’-Monophosphate Accumulation in Normal Human Thyroid Cell Cultures

1986 ◽  
Vol 62 (6) ◽  
pp. 1199-1205 ◽  
Author(s):  
MARIA LUISA BRANDI ◽  
CARLO M. ROTELLA ◽  
LEONARD D. KOHN ◽  
RONERTO TOCCAFONDI
Keyword(s):  
Cholera Toxin ◽  
Vasoactive Intestinal Peptide ◽  
Cell Cultures ◽  
Human Thyroid ◽  
Thyroid Cell ◽  
Thyroid Stimulating Antibodies ◽  
Normal Human ◽  
Human Thyroid Cell

Effect of Graves' IgG on gene transcription in human thyroid cell cultures Thyroglobulin gene activation

FEBS Letters ◽  
1988 ◽  
Vol 232 (1) ◽  
pp. 12-16 ◽  
Author(s):  
Annie W.C. Kung ◽  
Kate Collison ◽  
J.Paul Banga ◽  
Alan M. McGregor
Keyword(s):  
Gene Transcription ◽  
Cell Cultures ◽  
Gene Activation ◽  
Human Thyroid ◽  
Thyroid Cell ◽  
Thyroglobulin Gene ◽  
Human Thyroid Cell

Functionality of Thyroid-Stimulating Antibodies Assessed by Cryopreserved Human Thyroid Cell Bioassay*

1983 ◽  
Vol 57 (5) ◽  
pp. 1021-1027 ◽  
Author(s):  
TERRY F. DAVIES ◽  
MICHAEL PLATZER ◽  
ARTHUR SCHWARTZ ◽  
EUGENE FRIEDMAN
Keyword(s):  
Human Thyroid ◽  
Thyroid Cell ◽  
Thyroid Stimulating Antibodies ◽  
Human Thyroid Cell

Regulation of amino acid transport in rat and human thyroid cells

1989 ◽  
Vol 121 (6) ◽  
pp. 759-766
Author(s):  
C. M. Rotella ◽  
F. Piani ◽  
U. Frediani ◽  
R. Toccafondi
Keyword(s):  
Amino Acid ◽  
Cell Cultures ◽  
Amino Acid Transport ◽  
Human Thyroid ◽  
Thyroid Cell ◽  
Acid Transport ◽  
Thyroid Cells ◽  
Igf I ◽  
Rat Thyroid ◽  
Human Thyroid Cell

Abstract. To clarify the role of insulin, IGF-I and TSH in thyroid cell regulation, their effects on amino acid transport were studied separately. These effects were noted and compared using both the Wistar rat thyroid cell line and human thyroid cell cultures. Insulin, IGF-I and TSH were able independently to induce the radiolabelled α-aminoisobutyric acid transport within the rat thyroid cells: TSH stimulated the amino acid transport in rat thyroid cells in a dose-dependent way from 1 pmol/l to 10 nmol/l. Similarly, insulin increased amino acid transport significantly from 0.17 nmol/1 up to 0.17 μmol/l and IGF-I from 0.13 pmol/l up to 0.13 μmol/l. The combined effects of insulin and TSH on amino acid transport were equal to the theoretical sum of the activities, whereas those of IGF-I and TSH were greater than the theoretical one. When human thyroid cell cultures were used, a significant increase of labelled amino acid transport was induced by TSH, i.e. from 0.1 pmol/l to 10 pmol/l; IGF-I stimulated amino acid transport in a range from 0.13 pmol/l to 13 pmol/l, under the same conditions. Conversely, only large doses of insulin, i.e. 1.7 nmol/l, were able weakly to stimulate amino acid transport. When submaximal TSH and IGF-I doses were co-incubated in human thyroid cells, an additive effect on amino acid transport was observed.

Thyrotropin Receptor Autoantibodies Induce Human Thyroid Cell Growth and c-fosActivation*

1991 ◽  
Vol 72 (5) ◽  
pp. 1142-1147 ◽  
Author(s):  
G. K. HUBER ◽  
R. SAFIRSTEIN ◽  
D. NEUFELD ◽  
T. F. DAVIES
Keyword(s):  
Cell Growth ◽  
Human Thyroid ◽  
Thyroid Cell ◽  
Thyrotropin Receptor ◽  
Human Thyroid Cell

Productivity of Thyroglobulin and Thyroid Hormone on Human Thyroid Cell in Collagen Gel Culture

1995 ◽  
Vol 22 (2) ◽  
pp. 120-127 ◽  
Author(s):  
Takeshi Kusunoki ◽  
Shozo Nishida ◽  
Masahiro Koezuka ◽  
Kiyotaka Murata ◽  
Takanori Tomura
Keyword(s):  
Thyroid Hormone ◽  
Collagen Gel ◽  
Human Thyroid ◽  
Thyroid Cell ◽  
Collagen Gel Culture ◽  
Human Thyroid Cell ◽  
Gel Culture
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