Therapeutic Value of Lymph Node Dissection in Advanced Gastric Cancer with Macroscopic Duodenum Invasion: Is the Posterior Pancreatic Head Lymph Node Dissection Beneficial?

2009 ◽  
Vol 16 (5) ◽  
pp. 1241-1246 ◽  
Author(s):  
Masanori Tokunaga ◽  
Shigekazu Ohyama ◽  
Naoki Hiki ◽  
Tetsu Fukunaga ◽  
Harutaka Inoue ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Advanced Gastric Cancer ◽  
Lymph Node Dissection ◽  
Pancreatic Head ◽  
Node Dissection ◽  
Therapeutic Value

New method to evaluate the therapeutic value of lymph node dissection for gastric cancer

1995 ◽  
Vol 82 (3) ◽  
pp. 346-351 ◽  
Author(s):  
M. Sasako ◽  
P. McCulloch ◽  
T. Kinoshita ◽  
K. Maruyama
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Dissection ◽  
New Method ◽  
Node Dissection ◽  
Therapeutic Value

scholarly journals Comparison of laparoscopic versus open gastrectomy with D2 lymph node dissection for advanced gastric cancer: A meta-analysis

2019 ◽  
Vol 1 (2) ◽  
pp. 110-121
Author(s):  
Sandrie Mariella Mac ◽  
Ashish Bahadur Malla
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Advanced Gastric Cancer ◽  
Lymph Node Dissection ◽  
Meta Analysis ◽  
Disease Free Survival ◽  
Open Gastrectomy ◽  
Long Term Results ◽  
Node Dissection ◽  
D2 Lymph Node Dissection

For many decades, D2 procedure has been accepted in the far-east as the standard treatment for both early (EGC) and advanced gastric cancer (AGC). In case of AGC, the debate on the extent of nodal dissection has been open for many years in order to highlight the safety and efficacy of treatment, hence this study. A comprehensive literature research was performed in PubMed to identify studies that compared laparoscopic- assisted gastrectomy (LAG) and open gastrectomy (OG) with D2 lymph node dissection (D2-LND) for treatment of AGC for the last five years. Data of interest were checked and subjected to meta-analysis with RevMan 5.3 software. The pooled risk ratios (RR) and weighted mean difference (WMD) with 95% confidence intervals (CI) were calculated. Overall, 19 studies were included in this meta-analysis. LG had some advantages over OG, including shorter hospitalization (WMD -2.31; 95% CI -4.09 to -0.53; P = 0.01), less blood loss (WMD -120.49; 95% CI -174.27 to -66.71; P < 0.01), faster bowel recovery (WMD -0.55; 95% CI -0.86 to -0.24; P ˂ 0.01) and earlier ambulation (WMD -0.75; 95% CI -1.38 to -0.11; P = 0.02). In terms of surgical and oncological safety, LG could achieve similar lymph nodes (WMD, -0.94, 95% CI, -2.95 to 1.06; P=0.36), a lower complication rate [odds ratio (OR)=0.80; 95%CI, 0.68-0.97; P=0.02], and overall survival (OS) and disease-free survival (DFS) comparable to OG. In conclusion, for AGCs both techniques (LAG and OG) appeared comparable in short- and long-term results. More time was needed to perform LAG; nonetheless, it had some advantages in achieving faster postoperative recovery over OG. In order to clarify this controversial issue ongoing trials and future studies are needed.

scholarly journals Lymph Node Dissection in Resectable Advanced Gastric Cancer

2013 ◽  
Vol 30 (2) ◽  
pp. 96-103 ◽  
Author(s):  
Wobbe O. de Steur ◽  
Johan L. Dikken ◽  
Henk H. Hartgrink
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Advanced Gastric Cancer ◽  
Lymph Node Dissection ◽  
Node Dissection

scholarly journals Prophylactic lymph node dissection in patients with advanced gastric cancer promotes increased survival time

Cancer ◽  
1992 ◽  
Vol 70 (2) ◽  
pp. 392-395 ◽  
Author(s):  
Yoshihiko Maehara ◽  
Toshiro Okuyama ◽  
Sunao Moriguchi ◽  
Hiroyuki Orita ◽  
Hiroki Kusumoto ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Survival Time ◽  
Advanced Gastric Cancer ◽  
Lymph Node Dissection ◽  
Node Dissection ◽  
Prophylactic Lymph Node Dissection
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