scholarly journals In Vitro and in Vivo Anti-oxidant Activity of Hot Water Extract of Basidiomycetes-X, Newly Identified Edible Fungus

2008 ◽  
Vol 31 (1) ◽  
pp. 111-117 ◽  
Author(s):  
Tetsuo Watanabe ◽  
Yuki Nakajima ◽  
Tetsuya Konishi
Keyword(s):  
Water Extract ◽  
Hot Water ◽  
Edible Fungus ◽  
Hot Water Extract ◽  
Anti Oxidant

scholarly journals Anti-inflammatory Effect of Onion (Allium cepa) Peel Hot Water Extract in vitro and in vivo

KSBB Journal ◽  
2015 ◽  
Vol 30 (4) ◽  
pp. 148-154
Author(s):  
Bo-Kyeong Kang ◽  
Koth-Bong-Woo-Ri Kim ◽  
Na-Kyung Ahn ◽  
Yeon-Uk Choi ◽  
Min-ji Kim ◽  
...  
Keyword(s):  
Allium Cepa ◽  
Water Extract ◽  
Hot Water ◽  
Hot Water Extract ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Anti-Obesity Effect of Hot Water Extract of Barley Sprout through the Inhibition of Adipocyte Differentiation and Growth

Metabolites ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 610
Author(s):  
Myeong-Jin Kim ◽  
Hye-Won Kawk ◽  
Sang-Hyeon Kim ◽  
Hy-Jae Lee ◽  
Ji-Won Seo ◽  
...  
Keyword(s):  
Adipocyte Differentiation ◽  
Morphological Changes ◽  
Water Extract ◽  
Inhibitory Effect ◽  
Hot Water ◽  
Blood Biochemical ◽  
Hot Water Extract ◽  
Model Weight

Barley sprouts are known to have several effective physiological activities. In this study, the anti-obesity effect of a barley sprout hot water extract (BSE) was confirmed. Saponarin was quantitatively analyzed in BSE using HPLC, and the inhibitory effect on 3T3-L1 pre-adipocyte differentiation into adipocytes was confirmed by Oil Red O staining, TG assay, and Western blotting. In addition, the inhibitory effect of BSE on adipocyte growth was confirmed through glucose uptake and lipolysis of adipocytes. C57/BL/6N mice were induced to obesity with a high-fat diet, and BSE was administered to confirm the effect on an animal model. Weight gain, morphological changes in adipose tissue, changes in the food efficiency ratio, and blood biochemical changes were observed, and an improvement effect on fatty liver was confirmed. As a result, the anti-obesity effect of BSE was confirmed in vitro, and it was confirmed that this effect was also effective in vivo and that it could be helpful in the treatment of obesity-related diseases.

Effects of a Hot-Water Extract of Allium hookeri Roots on Bone Formation in Human Osteoblast-Like MG-63 Cells In Vitro and in Rats In Vivo

Planta Medica ◽  
2016 ◽  
Vol 82 (16) ◽  
pp. 1410-1415 ◽  
Author(s):  
Heajin Park ◽  
Jaehoon Jeong ◽  
Hanbit Hyun ◽  
Jihye Kim ◽  
Haesung Kim ◽  
...  
Keyword(s):  
Bone Formation ◽  
Water Extract ◽  
Hot Water ◽  
Human Osteoblast ◽  
Allium Hookeri ◽  
Hot Water Extract

scholarly journals Raphanus sativus ameliorates atherogeneic lipid profiles in hypercholesterolemic rats and hypercholesterolemia-associated peroxidative liver damage

2011 ◽  
Vol 7 (3) ◽  
pp. 1385-1394 ◽  
Author(s):  
Mozammel Haque ◽  
Jahirul Islam ◽  
Asiqur Rahaman ◽  
Fowzia Akter Selina ◽  
Mohammad Azizur Rahman ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Raphanus Sativus ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Water Extract ◽  
Density Lipoprotein ◽  
Lipid Peroxide ◽  
Hot Water

Objective: Raphanus sativus is a hugely used edible root vegetable. We investigated whether the feeding of the Raphanus sativus hot water extract (RSE) ameliorates atherogenic lipid profile and oxidative stress in hypercholesterolemia. Methods: After feeding of the RSE to hypercholesterolemic rats for 6 weeks, the levels of plasma and hepatic total cholesterol (TC), triglyceride (TG), and plasma high density lipoprotein-cholesterol (HDL-C) and fecal TC levels were studied. The effects of RSE on the hepatic enzymes, namely alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP), the levels of lipid peroxide (LPO) and liver histology were also evaluated. Results: Hypercholesterolemia increased the levels of TC and TG in the plasma and livers. The levels of ALT, AST and ALP in plasma and LPO in the liver also increased. The dietary RSE, however, significantly ameliorated the above atherogenic lipids and liver enzymes. The RSE significantly reduced the levels of LPO in the liver, suggesting an in vivo protection against of oxidative stress. The RSE also inhibited the in vitro Fenton’s reagent-induced oxidative stress, thus corroborating the in vivo anti-LPO actions of RSE. The levels of hepatic LPO were positively correlated with plasma AST (r=0.76; P <0.05) and ALT (r=0.43; P<0.05) levels. Histologically, the livers of the RSE-fed hypercholesterolemic rats exhibited lesser fatty droplets and reduced inflammatory cells. Conclusion: Finally, R. sativus extract lowers the cardiovascular disease risk factors under hypercholesterolemic situation by increasing the plasma/hepatic clearance of cholesterol and improving the hypercholesterolemia-induced oxidative damage of hepatic tissues.

scholarly journals Giloy (Tinospora Cordifolia): In Vitro Evaluation of Antibacterial Properties

2021 ◽  
Vol 07 (06) ◽  
Author(s):  
Tulsa Devi ◽  
Keyword(s):  
Antibacterial Activity ◽  
Methanolic Extract ◽  
Water Extract ◽  
Hot Water ◽  
Tinospora Cordifolia ◽  
Diffusion Method ◽  
Zone Of Inhibition ◽  
Hot Water Extract ◽  
Agar Well Diffusion Method

Antibiotic resistance has become a global concern and hence, the search for other source of antimicrobials initiated to find a way to control infections in future. The main objective of this paper is to screen Giloy (Tinospora cordifolia) for its antibacterial activity. The stem of Tinospora cordifolia is used to prepare extract for determining it’s in vitro antibacterial activity as per the agar well diffusion method. In the agar well diffusion method 100μl of 24 hr broth culture of bacteria was aseptically and evenly swabbed on Mueller Hinton agar plates. Wells of about 8 mm diameter were aseptically cut using sterile cork-borer. 100 μl of plant extracts of different concentrations were then placed into the separate wells. The plates were incubated at 37 oC for 24hr. Antimicrobial activity of the giloy was determined by measuring the diameter of zone of inhibition. The methanolic extract of Tinospora cordifolia showed 13, 11, 9 and 5 mm zone of inhibition in S. aureus cultures by using 100, 75, 50 and 25 mg/ml concentration, respectively while hot water extract of Tinospora cordifolia showed 14, 12, 10 and 8 mm zone of inhibition for S. aureus by using 100, 75, 50 and 25 mg/ml concentration, respectively and the cold extract of Tinospora cordifolia showed 10, 8, 5 and 0 mm zone of inhibition for S. aureus by using 100, 75, 50 and 25mg/ml concentration, respectively. The methanolic extract of Tinospora cordifolia indicated 12, 10, 6 and 4 mm zone of inhibition in cultures of E.coli by using 100, 75, 50 and 25 mg/ml concentration, respectively and the hot water extract of Tinospora cordifolia showed 16, 14, 12 and 10 mm zone of inhibition in cultures of E.coli by using 100, 75, 50 and 25mg/ml concentration, respectively. The cold water extract of Tinospora cordifolia showed 13, 10, 8, and 5 mm zone of inhibition in cultures of E.coli by using 100, 75, 50 and 25 mg/ml concentration, respectively. It has been observed that Tinospora cordifolia showed very promising results as indicated by the zone of inhibition of bacterial culture through agar well diffusion method that varies from few mm to few cm. This study indicates the in-vitro antibacterial effect of Giloy which needs further validation through in-vivo studies.

scholarly journals Evaluation of an EpitypifiedOphiocordyceps formosana(Cordyceps s.l.) for Its Pharmacological Potential

2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Yen-Wen Wang ◽  
Tzu-Wen Hong ◽  
Yu-Ling Tai ◽  
Ying-Jing Wang ◽  
Sheng-Hong Tsai ◽  
...  
Keyword(s):  
Phylogenetic Analyses ◽  
Morphological Characteristics ◽  
Water Extract ◽  
Hot Water ◽  
Clinical Complications ◽  
Molecular Phylogenetic ◽  
Potential Applicability ◽  
Pharmacological Potential

The substantial merit ofCordyceps s.l.spp. in terms of medicinal benefits is largely appreciated. Nevertheless, only few studies have characterized and examined the clinical complications of the use of health tonics containing these species. Here, we epitypifiedC. formosanaisolates that were collected and characterized asOphiocordyceps formosanabased on morphological characteristics, molecular phylogenetic analyses, and metabolite profiling. Thus, we renamed and transferredC. formosanato the new protologueOphiocordyceps formosana(Kobayasi & Shimizu) Wang, Tsai, Tzean & Shencomb. nov.Additionally, the pharmacological potential ofO. formosanawas evaluated based on the hot-water extract from its mycelium. The relative amounts of the known bioactive ingredients that are unique toCordyceps s.l.species inO. formosanawere found to be similar to the amounts inO. sinensisandC. militaris, indicating the potential applicability ofO. formosanafor pharmacological uses. Additionally, we found thatO. formosanaexhibited antioxidation activitiesin vitroandin vivothat were similar to those ofO. sinensisandC. militaris. Furthermore,O. formosanaalso displayed conspicuously effective antitumor activity compared with the testedCordyceps s.l.species. Intrinsically,O. formosanaexhibited less toxicity than the otherCordycepsspecies. Together, our data suggest that the metabolites ofO. formosanamay play active roles in complementary medicine.

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