The Effects of Nightly Normobaric Hypoxia on Running Economy and Hemoglobin Mass

2006 ◽  
Vol 38 (Supplement) ◽  
pp. S524
Author(s):  
Mitsuo Neya ◽  
Taketeru Maegawa ◽  
Yasuko Kumai ◽  
Taisuke Enoki ◽  
Takashi Kawahara ◽  
...  
2007 ◽  
Vol 103 (3) ◽  
pp. 828-834 ◽  
Author(s):  
Mituso Neya ◽  
Taisuke Enoki ◽  
Yasuko Kumai ◽  
Takayuki Sugoh ◽  
Takashi Kawahara

We investigated the effects of nightly intermittent exposure to hypoxia and of training during intermittent hypoxia on both erythropoiesis and running economy (RE), which is indicated by the oxygen cost during running at submaximal speeds. Twenty-five college long- and middle- distance runners [maximal oxygen uptake (V̇o2max) 60.3 ± 4.7 ml·kg−1·min−1] were randomly assigned to one of three groups: hypoxic residential group (HypR, 11 h/night at 3,000 m simulated altitude), hypoxic training group (HypT), or control group (Con), for an intervention of 29 nights. All subjects trained in Tokyo (altitude of 60 m) but HypT had additional high-intensity treadmill running for 30 min at 3,000 m simulated altitude on 12 days during the night intervention. V̇o2 was measured at standing rest during four submaximal speeds (12, 14, 16, and 18 km/h) and during a maximal stage to volitional exhaustion on a treadmill. Total hemoglobin mass (THb) was measured by carbon monoxide rebreathing. There were no significant changes in V̇o2max, THb, and the time to exhaustion in all three groups after the intervention. Nevertheless, HypR showed ∼5% improvement of RE in normoxia ( P < 0.01) after the intervention, reflected by reduced V̇o2 at 18 km/h and the decreased regression slope fitted to V̇o2 measured during rest position and the four submaximal speeds ( P < 0.05), whereas no significant corresponding changes were found in HypT and Con. We concluded that our dose of intermittent hypoxia (3,000 m for ∼11 h/night for 29 nights) was insufficient to enhance erythropoiesis or V̇o2max, but improved the RE at race speed of college runners.


2003 ◽  
Vol 35 (Supplement 1) ◽  
pp. S115 ◽  
Author(s):  
L G. Myhre ◽  
I H. Muir ◽  
A B. Salazar ◽  
T Dahms

2017 ◽  
Vol 123 (2) ◽  
pp. 387-393 ◽  
Author(s):  
Anna Hauser ◽  
Severin Troesch ◽  
Jonas J. Saugy ◽  
Laurent Schmitt ◽  
Roberto Cejuela-Anta ◽  
...  

The purpose of this research was to compare individual hemoglobin mass (Hbmass) changes following a live high-train low (LHTL) altitude training camp under either normobaric hypoxia (NH) or hypobaric hypoxia (HH) conditions in endurance athletes. In a crossover design with a one-year washout, 15 male triathletes randomly performed two 18-day LHTL training camps in either HH or NH. All athletes slept at 2,250 meters and trained at altitudes <1,200 meters. Hbmass was measured in duplicate with the optimized carbon monoxide rebreathing method before (pre) and immediately after (post) each 18-day training camp. Hbmass increased similarly in HH (916–957 g, 4.5 ± 2.2%, P < 0.001) and in NH (918–953 g, 3.8 ± 2.6%, P < 0.001). Hbmass changes did not differ between HH and NH ( P = 0.42). There was substantial interindividual variability among subjects to both interventions (i.e., individual responsiveness or the individual variation in the response to an intervention free of technical noise): 0.9% in HH and 1.7% in NH. However, a correlation between intraindividual ΔHbmass changes (%) in HH and in NH ( r = 0.52, P = 0.048) was observed. HH and NH evoked similar mean Hbmass increases following LHTL. Among the mean Hbmass changes, there was a notable variation in individual Hbmass response that tended to be reproducible. NEW & NOTEWORTHY This is the first study to compare individual hemoglobin mass (Hbmass) response to normobaric and hypobaric live high-train low using a same-subject crossover design. The main findings indicate that hypobaric and normobaric hypoxia evoked a similar mean increase in Hbmass following 18 days of live high-train low. Notable variability and reproducibility in individual Hbmass responses between athletes was observed, indicating the importance of evaluating individual Hbmass response to altitude training.


2016 ◽  
Vol 48 (4) ◽  
pp. 734-741 ◽  
Author(s):  
ANNA HAUSER ◽  
LAURENT SCHMITT ◽  
SEVERIN TROESCH ◽  
JONAS J. SAUGY ◽  
ROBERTO CEJUELA-ANTA ◽  
...  

2015 ◽  
Vol 119 (8) ◽  
pp. 889-899 ◽  
Author(s):  
Oliver R. Gibson ◽  
Gareth Turner ◽  
James A. Tuttle ◽  
Lee Taylor ◽  
Peter W. Watt ◽  
...  

Heat acclimation (HA) attenuates physiological strain in hot conditions via phenotypic and cellular adaptation. The aim of this study was to determine whether HA reduced physiological strain, and heat shock protein (HSP) 72 and HSP90α mRNA responses in acute normobaric hypoxia. Sixteen male participants completed ten 90-min sessions of isothermic HA (40°C/40% relative humidity) or exercise training [control (CON); 20°C/40% relative humidity]. HA or CON were preceded (HYP1) and proceeded (HYP2) by a 30-min normobaric hypoxic exposure [inspired O2 fraction = 0.12; 10-min rest, 10-min cycling at 40% peak O2 uptake (V̇o2 peak), 10-min cycling at 65% V̇o2 peak]. HA induced greater rectal temperatures, sweat rate, and heart rates (HR) than CON during the training sessions. HA, but not CON, reduced resting rectal temperatures and resting HR and increased sweat rate and plasma volume. Hemoglobin mass did not change following HA nor CON. HSP72 and HSP90α mRNA increased in response to each HA session, but did not change with CON. HR during HYP2 was lower and O2 saturation higher at 65% V̇o2 peak following HA, but not CON. O2 uptake/HR was greater at rest and 65% V̇o2 peak in HYP2 following HA, but was unchanged after CON. At rest, the respiratory exchange ratio was reduced during HYP2 following HA, but not CON. The increase in HSP72 mRNA during HYP1 did not occur in HYP2 following HA. In CON, HSP72 mRNA expression was unchanged during HYP1 and HYP2. In HA and CON, increases in HSP90α mRNA during HYP1 were maintained in HYP2. HA reduces physiological strain, and the transcription of HSP72, but not HSP90α mRNA in acute normobaric hypoxia.


Author(s):  
Pavel F. Kiku ◽  
Evgeniy V. Zhovnerchuk ◽  
Irina P. Melnikova ◽  
Natalya I. Izmerovа ◽  
Kseniya M. Sabirova

Introduction.Occupational environment and occupational factors determine peculiarities in mastering marine occupations. Some unfavorable occupational educational and ecologic factors appear to cause high level of physical and psychoemotional stress.Objectiveis to study features of adaptation to study during occupational training in marine specialties in cadets of a higher marine educational institution, and to conduct medical and psychological rehabilitation.Material and methods.Examination covered 120 male cadets of 3rd and 4thyears of study: 70 (main group) and 50 (reference group). The age of the cadets was 21±0.4 years. To study characteristics of the cadets’ adaptation, the authors used psychological methods — Spielberger’s State Trait Anxiety Scale and Nemchin’s «Method measuring severity of neuropsychic stress». Statistical analysis was performed with software «Statistica for Windows 10.0».Study results and discussion.After 3 months of sailing, majority of the cadets appeared to be dysadapted. Deep clinical and laboratory studies proved that 39.4% of the examinees were apparently healthy and 60.6% of those had chronic diseases. Thus, a system of medical psychologic rehabilitation was designed, comprising primary and secondary prophylaxis methods. One of these prevention methods is a recovery complex of measures with intermittent normobaric hypoxia modified by us. The authors determined optimal regime of using intermittent normobaric hypoxia combined with medical rehabilitation.Conclusions.Adaptational state in cadets of high marine educational institution during professional training in marine occupations is characterized by increased psycho-emotional strain, anxiety and observed in 57.3% of the examinees. Findings are that after 3 months of sailing, majority of the cadets are dysadapted. To prevent morbidity and preserve health, the authors suggested a system of medical and psychologic rehabilitation including intermittent normobaric hypoxia with rehabilitation medical complex. The medical and prophylactic measures help to solve problems of psycho-emotional stress, lower morbidity parameters, prevent dysadaptation disorders, relieve functional overstrain. That preserves and improves the cadets’ health and forms an important stage in prevention of mental and behavioral disorders related to work.


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