scholarly journals Clinical Application Of Duke Activity Status Index To Select An Appropriate Cardiovascular Stress Test Protocol

2020 ◽  
Vol 52 (7S) ◽  
pp. 635-635
Author(s):  
Mary Ann Reynolds ◽  
Rachel Myers ◽  
Josh West ◽  
Katey Sweat ◽  
Virginia McGhee ◽  
...  
Keyword(s):  
Clinical Application ◽  
Stress Test ◽  
Test Protocol ◽  
Cardiovascular Stress ◽  
Duke Activity Status Index ◽  
Status Index

scholarly journals Duke Activity Status Index for Cardiovascular Diseases: Validation of the Portuguese Translation

2014 ◽  
Author(s):  
Mariana A. Coutinho-Myrrha ◽  
Rosângela C. Dias ◽  
Aline A. Fernandes ◽  
Christiano G. Araújo ◽  
Mark A. Hlatky ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Duke Activity Status Index ◽  
Status Index

Relation of clinical and angiographic factors to functional capacity as measured by the Duke Activity Status Index

1991 ◽  
Vol 68 (9) ◽  
pp. 973-975 ◽  
Author(s):  
Charlotte L. Nelson ◽  
James E. Herndon ◽  
Daniel B. Mark ◽  
David B. Pryor ◽  
Robert M. Califf ◽  
...  
Keyword(s):  
Functional Capacity ◽  
Duke Activity Status Index ◽  
Status Index

scholarly journals Microvascular Assessment of Ranolazine in Non-Obstructive Atherosclerosis

2020 ◽  
Vol 13 (12) ◽  
Author(s):  
Jin-Sin Koh ◽  
Olivia Y. Hung ◽  
Parham Eshtehardi ◽  
Arnav Kumar ◽  
Rani Rabah ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Nonobstructive Coronary Artery Disease ◽  
Angina Frequency ◽  
Duke Activity Status Index ◽  
Artery Disease ◽  
Status Index ◽  
Frequency Score

Background: Microvascular dysfunction is known to play a key role in patients with angina and nonobstructive coronary artery disease. We investigated the impact of ranolazine among patients with angina and nonobstructive coronary artery disease. Methods: In this randomized, double-blinded, placebo-controlled pilot trial, 26 patients with angina once weekly or more, abnormal stress test, and nonobstructive coronary artery disease (<50% stenosis by angiography and fractional flow reserve >0.80) were randomized 1:1 to ranolazine or placebo for 12 weeks. Primary end point was ΔSeattle Angina Questionnaire (SAQ) angina frequency score. Baseline and 3 months follow-up SAQ, Duke Activity Status Index scores along with invasive fractional flow reserve, coronary flow reserve (CFR), hyperemic myocardial resistance, and cardiopulmonary exercise testing measurements were performed. Results: No significant differences in ΔSAQ angina frequency scores ( P =0.53) or Duke Activity Status Index ( P =0.76) were observed between ranolazine versus placebo, although patients on ranolazine had lesser improvement in SAQ physical limitation scores ( P =0.02) compared with placebo at 3 months. There were no significant differences in ΔCFR or Δhyperemic myocardial resistance between ranolazine and placebo groups. Patients treated with ranolazine, compared with placebo, had no significant improvement in maximum rate of oxygen consumption measured during incremental exercise (VO 2 max) and peak metabolic equivalents of task. Interestingly, in the ranolazine group, patients with baseline CFR<2.0 demonstrated greater gain in CFR compared with those with baseline CFR≥2.0 ( P =0.02). Conclusions: Ranolazine did not demonstrate improvement in SAQ angina frequency score, invasive microvascular function, or peak metabolic equivalent compared with placebo at 3 months. Registration: URL: https://www.clinicaltrials.gov . Unique identifier: NCT02147067.

Middle Ear Obliteration with Blind-Sac Closure of the External Auditory Canal for Spontaneous CSF Otorrhea

2016 ◽  
Vol 156 (3) ◽  
pp. 534-542 ◽  
Author(s):  
Shawn M. Stevens ◽  
Ryan Crane ◽  
Myles L. Pensak ◽  
Ravi N. Samy
Keyword(s):  
Body Mass Index ◽  
Cerebrospinal Fluid ◽  
Body Mass ◽  
Middle Ear ◽  
External Auditory Canal ◽  
Cardiac Risk ◽  
Mastoid Obliteration ◽  
Duke Activity Status Index ◽  
Blind Sac Closure ◽  
Status Index

Outcome Objectives To (1) identify unique features of patients who underwent middle ear/mastoid obliteration with blind-sac closure of the external auditory canal for spontaneous cerebrospinal fluid (CSF) otorrhea and (2) explore outcomes. Study Design Case series with chart review. Setting Tertiary care center. Subjects and Methods Adults treated for spontaneous cerebrospinal fluid otorrhea from 2007 through 2015 were reviewed and stratified into 2 groups based on the surgery performed: (1) 11 patients underwent middle ear/mastoid obliteration with blind-sac closure of the external auditory canal and (2) 26 patients underwent other procedures. Demographics, body mass index, revised cardiac risk index, Duke Activity Status Index scores, and anticoagulation use were documented. Audiologic data were gathered from pre- and postoperative visits. The primary outcome measure was leak recurrence. Complications were tabulated. Results Poor preoperative hearing was a relative indication for obliteration. Obliteration patients had higher body mass index (43.2 vs 34.9 kg/m2; P < .05), incidence of super-morbid obesity (45% vs 7.6%; P = .015), anticoagulation usage (36% vs 0%; P = .004), cardiac risk scores (1.2 vs 0.1 dB; P < .0004), and Duke Activity Status Index scores. There was 1 leak recurrence (9%). Major and minor complication rates were 9% and 36%, respectively. Mean follow-up was 30.8 ± 8.6 months. Conclusion Middle ear and mastoid obliteration with blind-sac closure of the external auditory canal is effective for treating spontaneous CSF otorrhea. The small cohort reviewed did not experience any major perioperative morbidity. The technique may be best suited for patients with poor hearing, the infirm, and those in whom craniotomy is contraindicated.

Psychometric testing of the Duke Activity Status Index in patients with heart failure

2014 ◽  
Vol 14 (3) ◽  
pp. 214-221 ◽  
Author(s):  
Xiuzhen Fan ◽  
Kyoung Suk Lee ◽  
Susan K Frazier ◽  
Terry A Lennie ◽  
Debra K Moser
Keyword(s):  
Heart Failure ◽  
Psychometric Testing ◽  
Patients With Heart Failure ◽  
Duke Activity Status Index ◽  
Status Index

scholarly journals A Comparative Study of Dynamic Load Response of High Temperature PEM Fuel Cells

2020 ◽  
Vol 24 (1) ◽  
pp. 529-544
Author(s):  
Martin Tomas ◽  
Pavel Novotny ◽  
Fatemeh Gholami ◽  
Ondrej Tucek ◽  
Frantisek Marsik
Keyword(s):  
High Temperature ◽  
Fuel Cell ◽  
Power Systems ◽  
Comparative Study ◽  
Electrochemical Impedance ◽  
Platinum Catalyst ◽  
Stress Test ◽  
Pem Fuel Cells ◽  
Cell Performance ◽  
Test Protocol

Abstract The high temperature polymer electrolyte membrane fuel cell (HT-PEMFC) based on the polybenzimidazole (PBI) membrane doped with phosphoric acid (H3PO4) presents a promising route in the development of fuel cell technology. The higher operating temperature of 160–200 °C results in an increased tolerance of the platinum catalyst to the carbon monoxide, an improved electrode kinetics, a higher-grade heat produced by the fuel cell, and a simplified water management due to the absence of liquid water in the system. In this study, the accelerated stress test protocol (AST) corresponding to the Driving Duty Cycle was used to characterize two sets of commercial MEAs, by Danish Power Systems Ltd. and FuMA-tech GmbH, respectively. Performance characteristics prior to and after the AST procedure were measured. The changes in the resistivity of the MEA were examined by electrochemical impedance spectroscopy (EIS). The EIS data were analysed and interpreted by a suitable equivalent circuit that consisted of a resistor and the Voigt’s structure in series with constant phase elements. Conducted experiments and their analysis showed suitability of the HT-PEMFC technology in applications where dynamical load of the cell is expected. Moreover, the lower number of AST cycles did not seriously affect the cell performance. As expected, with increasing number of AST cycles, decrease in the cell performance was observed. In general, presented comparative study is expected to provide an extension of existing data for present and future development of diagnostic in the field of HT-PEMFC.

Sign in / Sign up

Export Citation Format

Share Document